Peter Laux
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View article: Characteristics of a tattooed population and a possible role of tattoos as a risk factor for chronic diseases: Results from the LIFE-Adult-Study
Characteristics of a tattooed population and a possible role of tattoos as a risk factor for chronic diseases: Results from the LIFE-Adult-Study Open
Tattoos and permanent make-up (PMU) gain increasing popularity among the general population. There are indications that pigments or their fragments may translocate within the body, however knowledge about possible systemic adverse effects …
View article: Smoking Topography, Nicotine Kinetics, and Subjective Smoking Experience of Mentholated and Non-Mentholated Heated Tobacco Products in Occasional Smokers
Smoking Topography, Nicotine Kinetics, and Subjective Smoking Experience of Mentholated and Non-Mentholated Heated Tobacco Products in Occasional Smokers Open
Background: Heated tobacco products (HTPs) are marketed as reduced-harm alternatives to conventional cigarettes (CCs) and are increasingly used by young adults and occasional smokers. However, their acute nicotine delivery and user experie…
View article: Bioinspired Soft Machines: Engineering Nature’s Grace into Future Innovations
Bioinspired Soft Machines: Engineering Nature’s Grace into Future Innovations Open
This article explores the transformative advances in soft machines, where biology, materials science, and engineering have converged. We discuss the remarkable adaptability and versatility of soft machines, whose designs draw inspiration f…
View article: Developing a Multi-Method Approach for Understanding Cellular Uptake and Biological Response: Investigating Co-Exposure of Macrophage-like Differentiated THP-1 Cells to Al2O3 and CeO2 Nanoparticles
Developing a Multi-Method Approach for Understanding Cellular Uptake and Biological Response: Investigating Co-Exposure of Macrophage-like Differentiated THP-1 Cells to Al2O3 and CeO2 Nanoparticles Open
The use of different nanoparticles (NPs) is increasing in a wide variety of everyday products. Nevertheless, most studies concerning NP risk assessment have evaluated exposure scenarios involving a single kind of NP. A stepwise study disti…
View article: Applicability of In Silico New Approach Methods for the Risk Assessment of Tattoo Ink Ingredients
Applicability of In Silico New Approach Methods for the Risk Assessment of Tattoo Ink Ingredients Open
Tattoo inks contain several substances, including organic and inorganic pigments, additives, and solvents, which may pose a health risk to not only the tattooed skin but also to other parts of the human body due to intradermal exposure. Su…
View article: Characteristics of a tattooed population and a possible role of tattoos as a risk factor for chronic diseases: Results from the LIFE-Adult-Study
Characteristics of a tattooed population and a possible role of tattoos as a risk factor for chronic diseases: Results from the LIFE-Adult-Study Open
Tattoos and permanent make-up (PMU) gain increasing popularity among the general population. There are indications that pigments or their fragments may translocate within the body, however knowledge about possible systemic adverse effects …
View article: AI and ML-based risk assessment of chemicals: predicting carcinogenic risk from chemical-induced genomic instability
AI and ML-based risk assessment of chemicals: predicting carcinogenic risk from chemical-induced genomic instability Open
Chemical risk assessment plays a pivotal role in safeguarding public health and environmental safety by evaluating the potential hazards and risks associated with chemical exposures. In recent years, the convergence of artificial intellige…
View article: Investigating Tattoo Pigments Composition with UV-Vis and FT-IR Spectroscopy Supported by Chemometric Modelling
Investigating Tattoo Pigments Composition with UV-Vis and FT-IR Spectroscopy Supported by Chemometric Modelling Open
Aims: This study investigates the composition of tattoo pigments to ensure their safe application in tattoo art, evaluating the viability of UV-Vis and FT-IR spectroscopy, coupled with chemometrics, for predicting pigment contents in tatto…
View article: Small pouches, but high nicotine doses—nicotine delivery and acute effects after use of tobacco-free nicotine pouches
Small pouches, but high nicotine doses—nicotine delivery and acute effects after use of tobacco-free nicotine pouches Open
Tobacco-free nicotine pouches are new nicotine products for oral consumption. They can contain very high nicotine amounts that have not been addressed with clinical studies yet. Thus, nicotine delivery, effects on craving, and side effects…
View article: Lessons learned in a decade: Medical‐toxicological view of tattooing
Lessons learned in a decade: Medical‐toxicological view of tattooing Open
Tattooing has been part of the human culture for thousands of years, yet only in the past decades has it entered the mainstream of the society. With the rise in popularity, tattoos also gained attention among researchers, with the aim to b…
View article: Advancing Predictive Risk Assessment of Chemicals via Integrating Machine Learning, Computational Modeling, and Chemical/Nano‐Quantitative Structure‐Activity Relationship Approaches
Advancing Predictive Risk Assessment of Chemicals via Integrating Machine Learning, Computational Modeling, and Chemical/Nano‐Quantitative Structure‐Activity Relationship Approaches Open
The escalating use of novel chemicals and nanomaterials (NMs) across diverse sectors underscores the need for advanced risk assessment methods to safeguard human health and the environment. Traditional labor‐intensive approaches have given…
View article: ROS generating BODIPY loaded nanoparticles for photodynamic eradication of biofilms
ROS generating BODIPY loaded nanoparticles for photodynamic eradication of biofilms Open
Bacterial biofilms can pose a serious health risk to humans and are less susceptible to antibiotics and disinfection than planktonic bacteria. Here, a novel method for biofilm eradication based on antimicrobial photodynamic therapy utilizi…
View article: Analyzing Tattoo Pigments in a Laboratory Setting: Application of UV-Vis and FTIR Spectroscopy Methods supported with Chemometric Modelling
Analyzing Tattoo Pigments in a Laboratory Setting: Application of UV-Vis and FTIR Spectroscopy Methods supported with Chemometric Modelling Open
Physicochemical characterization of tattoo inks has a major impact on their safe usage in tattoo art. Analytical measurements of pigments used in tattoo inks is a real challenge when monitoring their quality. UV-Vis (ultraviolet visible) a…
View article: Oral nicotine pouches with an aftertaste? Part 2: in vitro toxicity in human gingival fibroblasts
Oral nicotine pouches with an aftertaste? Part 2: in vitro toxicity in human gingival fibroblasts Open
Nicotine pouches contain fewer characteristic toxicants than conventional tobacco products. However, the associated risks in terms of toxicity and addiction potential are still unclear. Therefore, endpoints of toxicity and contents of flav…
View article: Oral nicotine pouches with an aftertaste? Part 1: screening and initial toxicological assessment of flavorings and other ingredients
Oral nicotine pouches with an aftertaste? Part 1: screening and initial toxicological assessment of flavorings and other ingredients Open
Nicotine pouches are oral products that deliver nicotine without containing tobacco. Previous studies mainly focused on the determination of known tobacco toxicants, while yet no untargeted analysis has been published on unknown constituen…
View article: Two Different Heated Tobacco Products vs. Cigarettes: Comparison of Nicotine Delivery and Subjective Effects in Experienced Users
Two Different Heated Tobacco Products vs. Cigarettes: Comparison of Nicotine Delivery and Subjective Effects in Experienced Users Open
Heated tobacco products (HTPs) produce aerosol using a different mechanism than tobacco cigarettes, leading to lower emissions of some harmful substances, but also of nicotine as reported by some independent studies. Lower nicotine deliver…
View article: Usage Pattern and Nicotine Delivery during Ad Libitum Consumption of Pod E-Cigarettes and Heated Tobacco Products
Usage Pattern and Nicotine Delivery during Ad Libitum Consumption of Pod E-Cigarettes and Heated Tobacco Products Open
Many different nicotine delivery products, such as e-cigarettes (e-cigs) or heated tobacco products (HTPs), are available on the market. To better understand these products, it is crucial to learn how consumers use them and how much nicoti…
View article: Artificial intelligence and machine learning disciplines with the potential to improve the nanotoxicology and nanomedicine fields: a comprehensive review
Artificial intelligence and machine learning disciplines with the potential to improve the nanotoxicology and nanomedicine fields: a comprehensive review Open
The use of nanomaterials in medicine depends largely on nanotoxicological evaluation in order to ensure safe application on living organisms. Artificial intelligence (AI) and machine learning (MI) can be used to analyze and interpret large…
View article: Nanomaterial Characterization in Complex Media—Guidance and Application
Nanomaterial Characterization in Complex Media—Guidance and Application Open
A broad range of inorganic nanoparticles (NPs) and their dissolved ions possess a possible toxicological risk for human health and the environment. Reliable and robust measurements of dissolution effects may be influenced by the sample mat…
View article: Impact of phosphine and of sulfuryl fluoride fumigation on walnut quality
Impact of phosphine and of sulfuryl fluoride fumigation on walnut quality Open
Food products are often fumigated to protect them from pest damage and to meet phytosanitary requirements. While fumigants undergo a risk assessment prior to approval for use, additional studies are necessary to evaluate their effects on f…
View article: Coronavirus-mimicking nanoparticles (CorNPs) in artificial saliva droplets and nanoaerosols: Influence of shape and environmental factors on particokinetics/particle aerodynamics
Coronavirus-mimicking nanoparticles (CorNPs) in artificial saliva droplets and nanoaerosols: Influence of shape and environmental factors on particokinetics/particle aerodynamics Open
Severe acute respiratory syndrome coronavirus 2, abbreviated as SARS-CoV-2, has been associated with the transmission of infectious COVID-19 disease through breathing and speech droplets emitted by infected carriers including asymptomatic …
View article: Summary and derived Risk Assessment of 3D printing emission studies
Summary and derived Risk Assessment of 3D printing emission studies Open
Three-dimensional (3D) printing is an additive manufacturing process that increases in application and consumer popularity. Studies with 3D printers have shown that the printing process releases particles and volatile organic compounds (VO…
View article: Micropatterned Neurovascular Interface to Mimic the Blood–Brain Barrier’s Neurophysiology and Micromechanical Function: A BBB-on-CHIP Model
Micropatterned Neurovascular Interface to Mimic the Blood–Brain Barrier’s Neurophysiology and Micromechanical Function: A BBB-on-CHIP Model Open
A hybrid blood–brain barrier (BBB)-on-chip cell culture device is proposed in this study by integrating microcontact printing and perfusion co-culture to facilitate the study of BBB function under high biological fidelity. This is achieved…