Peter Lundgren
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View article: Multi-modal deep-learning troponin prediction from electrocardiograms and demographic data
Multi-modal deep-learning troponin prediction from electrocardiograms and demographic data Open
Aims Electrocardiograms (ECGs) and troponin (Tn) testing are essential tools for the diagnosis and management of cardiac conditions. Prompt diagnosis using these tools can significantly improve patient outcomes. Methods and results The obj…
View article: Factors influencing patients willingness to participate in clinical trials
Factors influencing patients willingness to participate in clinical trials Open
Background It is ethically challenging to obtain informed consent for participation in research studies in patients with altered mental status or unconsciousness. The aim of this study was to describe and explore factors influencing patien…
View article: Correction: The evidence supporting AHA guidelines on adult cardiopulmonary resuscitation (CPR)
Correction: The evidence supporting AHA guidelines on adult cardiopulmonary resuscitation (CPR) Open
[This corrects the article DOI: 10.1371/journal.pone.0309241.].
View article: Predicting 30-day survival after in-hospital cardiac arrest: a nationwide cohort study using machine learning and SHAP analysis
Predicting 30-day survival after in-hospital cardiac arrest: a nationwide cohort study using machine learning and SHAP analysis Open
Objective In-hospital cardiac arrest (IHCA) presents a critical challenge with low survival rates and limited prediction tools. Despite advances in resuscitation, predicting 30-day survival remains difficult, and current methods lack inter…
View article: Vasopressin and steroids in addition to adrenaline in cardiac arrest (VAST-A) – A randomised pilot study
Vasopressin and steroids in addition to adrenaline in cardiac arrest (VAST-A) – A randomised pilot study Open
In this IHCA pilot study, randomisation to adrenaline, vasopressin, and corticosteroids compared to controls was safe, but feasibility needs improvement for adequate enrolment in the VAST-A main study.
View article: The evidence supporting AHA guidelines on adult cardiopulmonary resuscitation (CPR)
The evidence supporting AHA guidelines on adult cardiopulmonary resuscitation (CPR) Open
Background Guidelines for the management of cardiac arrest play a crucial role in guiding clinical decisions and care. We examined the strength and quality of evidence underlying these recommendations in order to elucidate strengths and ga…
View article: Predicting troponin biomarker elevation from electrocardiograms using a deep neural network
Predicting troponin biomarker elevation from electrocardiograms using a deep neural network Open
Background Elevated troponin levels are a sensitive biomarker for cardiac injury. The quick and reliable prediction of troponin elevation for patients with chest pain from readily available ECGs may pose a valuable time-saving diagnostic t…
View article: The Pre-ECPR Score: Developing and Validating a Multivariable Prediction Model for Favorable Neurological Outcomes in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation
The Pre-ECPR Score: Developing and Validating a Multivariable Prediction Model for Favorable Neurological Outcomes in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation Open
The Pre-ECPR score combines multiple weighted predictors to provide a single balanced probability of favorable outcomes in ECPR patient selection. In cross-validation, it demonstrated significantly more favorable discriminatory performance…
View article: Prediction of neurologic outcome after out-of-hospital cardiac arrest: An interpretable approach with machine learning
Prediction of neurologic outcome after out-of-hospital cardiac arrest: An interpretable approach with machine learning Open
The XGBoost machine learning model with 10 features available at the time of hospital admission showed good performance for predicting neurologic outcome after OHCA, with no apparent signs of overfitting.
View article: Hospitalized patients’ attitudes towards participating in a randomized control trial in case of a cardiac arrest
Hospitalized patients’ attitudes towards participating in a randomized control trial in case of a cardiac arrest Open
Among hospitalized patients the vast majority gave informed consent to inclusion in an ongoing randomized cardiac arrest drug trial. The main reason for approving inclusion was to contribute to research.
View article: Changes in temperature in preheated crystalloids at ambient temperatures relevant to a prehospital setting: an experimental simulation study with the application of prehospital treatment of trauma patients suffering from accidental hypothermia
Changes in temperature in preheated crystalloids at ambient temperatures relevant to a prehospital setting: an experimental simulation study with the application of prehospital treatment of trauma patients suffering from accidental hypothermia Open
Background Accidental hypothermia is common in all trauma patients and contributes to the lethal diamond, increasing both morbidity and mortality. In hypotensive shock, fluid resuscitation is recommended using fluids with a temperature of …
View article: Prediction of survival in out-of-hospital cardiac arrest: the updated Swedish cardiac arrest risk score (SCARS) model
Prediction of survival in out-of-hospital cardiac arrest: the updated Swedish cardiac arrest risk score (SCARS) model Open
Aims Out-of-hospital cardiac arrest (OHCA) is a major health concern worldwide. Although one-third of all patients achieve a return of spontaneous circulation and may undergo a difficult period in the intensive care unit, only 1 in 10 surv…
View article: The capacity of neurological pupil index to predict the absence of somatosensory evoked potentials after cardiac arrest – An observational study
The capacity of neurological pupil index to predict the absence of somatosensory evoked potentials after cardiac arrest – An observational study Open
In this limited cohort, NPi < 3.4 in patients remaining comatose >48 hours after cardiac arrest predicted bilateral loss of the SSEP N20 response with a FPR < 5%. If validated in a larger cohort, an NPi threshold may be clinically applied …
View article: Early ICD implantation following out-of-hospital cardiac arrest: a retrospective cohort study from the Swedish Registry for Cardiopulmonary Resuscitation
Early ICD implantation following out-of-hospital cardiac arrest: a retrospective cohort study from the Swedish Registry for Cardiopulmonary Resuscitation Open
Background It is unclear whether an implantable cardioverter-defibrillator (ICD) is generally beneficial in survivors of out-of-hospital cardiac arrest (OHCA). Objective We studied the association between ICD implantation prior to discharg…
View article: Enhancing Atrial Fibrillation Prediction Using Multimodal Neural Networks and XGBoost Integration
Enhancing Atrial Fibrillation Prediction Using Multimodal Neural Networks and XGBoost Integration Open
Atrial fibrillation (AF), a prevalent cardiac arrhythmia, poses significant health risks, emphasizing the critical need for accurate and timely detection to develop robust methodologies and ensure effective intervention. This study propels…
View article: The evidence supporting AHA guidelines on adult cardiopulmonary resuscitation (CPR)
The evidence supporting AHA guidelines on adult cardiopulmonary resuscitation (CPR) Open
Background Guidelines for the management of cardiac arrest play a crucial role in guiding clinical decisions and care. We examined the strength and quality of evidence underlying these recommendations in order to elucidate strengths and ga…
View article: Aetiology and outcome in hospitalized cardiac arrest patients
Aetiology and outcome in hospitalized cardiac arrest patients Open
Aims To study aetiologies of in-hospital cardiac arrests (IHCAs) and their association with 30-day survival. Methods and results Observational study with data from national registries. Specific aetiologies (n = 22) of IHCA patients between…
View article: Temporal variation in survival following in-hospital cardiac arrest in Sweden
Temporal variation in survival following in-hospital cardiac arrest in Sweden Open
Patients suffering an IHCA have an increased chance of survival during the day vs the evening vs night, and the difference in survival is even more pronounced when cared for at smaller, non-academic hospitals, general wards and wards witho…
View article: Effect of Smartphone Dispatch of Volunteer Responders on Automated External Defibrillators and Out-of-Hospital Cardiac Arrests
Effect of Smartphone Dispatch of Volunteer Responders on Automated External Defibrillators and Out-of-Hospital Cardiac Arrests Open
Importance Smartphone dispatch of volunteer responders to nearby out-of-hospital cardiac arrests (OHCAs) has emerged in several emergency medical services, but no randomized clinical trials have evaluated the effect on bystander use of aut…
View article: Trends in survival after cardiac arrest: a Swedish nationwide study over 30 years
Trends in survival after cardiac arrest: a Swedish nationwide study over 30 years Open
Aims Trends in characteristics, management, and survival in out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) were studied in the Swedish Cardiopulmonary Resuscitation Registry (SCRR). Methods and results The SCRR…