Peter McCartney
YOU?
Author Swipe
View article: Endotyping-informed therapy for patients with chest pain and no obstructive coronary artery disease: a randomized trial
Endotyping-informed therapy for patients with chest pain and no obstructive coronary artery disease: a randomized trial Open
Patients undergoing invasive coronary angiography for the investigation of chest pain commonly do not have obstructive coronary artery disease. In contemporary practice, most of these individuals do not undergo functional diagnostic tests,…
View article: Latent Cytomegalovirus Infection Is Associated With Impaired Left Ventricular Function After ST‐Segment–Elevation Myocardial Infarction
Latent Cytomegalovirus Infection Is Associated With Impaired Left Ventricular Function After ST‐Segment–Elevation Myocardial Infarction Open
Background Human cytomegalovirus is a herpes virus that affects most individuals globally and may increase the risk of cardiovascular disease. Whether cytomegalovirus influences outcomes after ST‐segment–elevation myocardial infarction (ST…
View article: Coronary microvascular function and atherosclerotic plaque burden in ischaemia and no obstructive coronary arteries: a secondary analysis of the CorMicA trial
Coronary microvascular function and atherosclerotic plaque burden in ischaemia and no obstructive coronary arteries: a secondary analysis of the CorMicA trial Open
Background The relationship between atherosclerosis and endotypes of myocardial ischaemia with no obstructive coronary artery disease (INOCA) is unclear. We investigated potential associations between cumulative atherosclerotic plaque burd…
View article: Bail-out glycoprotein IIb/IIIa inhibitors for coronary microvascular obstruction: guideline-indicated, but does harm outweigh benefit?
Bail-out glycoprotein IIb/IIIa inhibitors for coronary microvascular obstruction: guideline-indicated, but does harm outweigh benefit? Open
Graphical AbstractBenefits and risks of glycoprotein IIb/IIIa inhibitor therapy for no-reflow.
View article: 208 Contrast derived indices of coronary microvascular function
208 Contrast derived indices of coronary microvascular function Open
Background and Aims Coronary function testing to measure index of microcirculatory resistance (IMR) and coronary flow reserve (CFR) may be performed at the time of invasive coronary angiography to aid the diagnosis of microvascular angina.…
View article: 20 Ischaemic late gadolinium enhancement in patients with myocardial infarction and no obstructive coronary arteries
20 Ischaemic late gadolinium enhancement in patients with myocardial infarction and no obstructive coronary arteries Open
Introduction Myocardial infarction with no obstructive coronary arteries (MINOCA) occurs in approximately 1 in 9 presentations with acute coronary syndrome. Cardiac MRI is guideline indicated in the investigation of aetiology for MINOCA wh…
View article: Fractional Flow Reserve-Guided Stent Optimisation in Focal and Diffuse Coronary Artery Disease
Fractional Flow Reserve-Guided Stent Optimisation in Focal and Diffuse Coronary Artery Disease Open
Assessing coronary physiology after stent implantation facilitates the optimisation of percutaneous coronary intervention (PCI). Coronary artery disease (CAD) patterns can be characterised by the pullback pressure gradient (PPG) index. The…
View article: Angina After Percutaneous Coronary Intervention: Patient and Procedural Predictors
Angina After Percutaneous Coronary Intervention: Patient and Procedural Predictors Open
Background: Twenty percent to 40% of patients are affected by angina after percutaneous coronary intervention (PCI), which is associated with anxiety, depression, impaired physical function, and reduced quality of life. Understanding patie…
View article: 27 Rationale and design of the effect of mineralocorticoid receptor antagonist therapy in patients with acute myocardial infarction or injury and non-obstructive coronary arteries: a registry-based, stratified-medicine, randomised, controlled trial
27 Rationale and design of the effect of mineralocorticoid receptor antagonist therapy in patients with acute myocardial infarction or injury and non-obstructive coronary arteries: a registry-based, stratified-medicine, randomised, controlled trial Open
Background Myocardial infarction and non-obstructive coronary arteries (MINOCA) affects 1 in 9 patients with acute coronary syndrome. Vascular pathophysiology includes atherothrombosis and coronary vasomotion disorders. MINOCA has an unmet…
View article: Differential Improvement in Angina and Health-Related Quality of Life After PCI in Focal and Diffuse Coronary Artery Disease
Differential Improvement in Angina and Health-Related Quality of Life After PCI in Focal and Diffuse Coronary Artery Disease Open
Residual angina after PCI was almost twice as common in patients with a low PPG (diffuse disease), whereas patients with a high PPG (focal disease) reported greater improvement in angina and quality of life. The baseline pattern of CAD can…
View article: Improvement in angina pectoris after percutaneous coronary interventions in focal and diffuse coronary artery disease
Improvement in angina pectoris after percutaneous coronary interventions in focal and diffuse coronary artery disease Open
Objective To investigate the effect of PCI on patient-reported outcomes in focal and diffuse coronary artery disease (CAD) as defined by the pullback pressure gradient (PPG). Background Improvements in fractional flow reserve (FFR) followi…
View article: Coronary perforation incidence and temporal trends (COPIT): systematic review and meta-analysis
Coronary perforation incidence and temporal trends (COPIT): systematic review and meta-analysis Open
Background Despite advancements in Percutaneous Coronary Intervention (PCI) technology and techniques, iatrogenic coronary artery perforation (CAP) remains a dreaded potential complication within the cardiac catheterisation laboratory. Dat…
View article: Coronary perforation incidence, outcomes and temporal trends (COPIT): a systematic review and meta-analysis
Coronary perforation incidence, outcomes and temporal trends (COPIT): a systematic review and meta-analysis Open
Coronary perforation is a potentially life-threatening complication of percutaneous coronary intervention (PCI). We studied incidence, outcomes and temporal trends following PCI-related coronary artery perforation (CAP). Methods Prospectiv…
View article: Coronary Artery Perforations: Glasgow Natural History Study of Covered Stent Coronary Interventions (GNOCCI) Study
Coronary Artery Perforations: Glasgow Natural History Study of Covered Stent Coronary Interventions (GNOCCI) Study Open
Background The objective of the GNOCCI (Glasgow Natural History Study of Covered Stent Coronary Interventions) Study was to report the incidence and outcomes of coronary artery perforations over an 18‐year period at a single, high‐volume p…
View article: Effect of low dose intracoronary alteplase on global circumferential strain (myocardial strain CMR substudy from the T-TIME trial)
Effect of low dose intracoronary alteplase on global circumferential strain (myocardial strain CMR substudy from the T-TIME trial) Open
Background Microvascular obstruction affects half of patients with ST-segment elevation myocardial infarction (STEMI) and confers an adverse prognosis. Feature-tracking (FT) cardiac magnetic resonance (CMR) allows myocardial strain assessm…
View article: Post-stenting fractional flow reserve vs coronary angiography for optimization of percutaneous coronary intervention (TARGET-FFR)
Post-stenting fractional flow reserve vs coronary angiography for optimization of percutaneous coronary intervention (TARGET-FFR) Open
Aims A fractional flow reserve (FFR) value ≥0.90 after percutaneous coronary intervention (PCI) is associated with a reduced risk of adverse cardiovascular events. TARGET-FFR is an investigator-initiated, single-centre, randomized controll…
View article: Thermodilution-derived temperature recovery time: a novel predictor of microvascular reperfusion and prognosis after myocardial infarction
Thermodilution-derived temperature recovery time: a novel predictor of microvascular reperfusion and prognosis after myocardial infarction Open
TRT represents a novel diagnostic advance for predicting MVO and prognosis. ClinicalTrials.gov Identifiers: NCT02072850 & NCT02257294 Visual summary. Thermodilution-derived temperature recovery time (TRT): a novel predictor of microvascula…
View article: Risk Stratification Guided by the Index of Microcirculatory Resistance and Left Ventricular End-Diastolic Pressure in Acute Myocardial Infarction
Risk Stratification Guided by the Index of Microcirculatory Resistance and Left Ventricular End-Diastolic Pressure in Acute Myocardial Infarction Open
Background: The index of microcirculatory resistance (IMR) of the infarct-related artery and left ventricular end-diastolic pressure (LVEDP) are acute, prognostic biomarkers in patients undergoing primary percutaneous coronary intervention…
View article: Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT
Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT Open
Background Microvascular obstruction commonly affects patients with acute ST-segment elevation myocardial infarction and is independently associated with adverse outcomes. Objective To determine whether or not a strategy involving low-dose…
View article: Comparative Significance of Invasive Measures of Microvascular Injury in Acute Myocardial Infarction
Comparative Significance of Invasive Measures of Microvascular Injury in Acute Myocardial Infarction Open
Background: The resistive reserve ratio (RRR) expresses the ratio between basal and hyperemic microvascular resistance. RRR measures the vasodilatory capacity of the microcirculation. We compared RRR, index of microcirculatory resistance (…
View article: Improving ultrasound video classification: an evaluation of novel deep learning methods in echocardiography
Improving ultrasound video classification: an evaluation of novel deep learning methods in echocardiography Open
Echocardiography is the commonest medical ultrasound examination, but automated interpretation is challenging and hinges on correct recognition of the 'view' (imaging plane and orientation). Current state-of-the-art methods for identifying…
View article: Low-Dose Alteplase During Primary Percutaneous Coronary Intervention According to Ischemic Time
Low-Dose Alteplase During Primary Percutaneous Coronary Intervention According to Ischemic Time Open
In patients presenting with ST-segment elevation myocardial infarction and an ischemic time ≥4 to 6 h, adjunctive treatment with low-dose intracoronary alteplase during primary percutaneous coronary intervention was associated with increas…
View article: Effects of Intracoronary Alteplase on Microvascular Function in Acute Myocardial Infarction
Effects of Intracoronary Alteplase on Microvascular Function in Acute Myocardial Infarction Open
Background Impaired microcirculatory reperfusion worsens prognosis following acute ST ‐segment–elevation myocardial infarction. In the T‐ TIME (A Trial of Low‐Dose Adjunctive Alteplase During Primary PCI) trial, microvascular obstruction o…
View article: Ischemia and No Obstructive Coronary Artery Disease
Ischemia and No Obstructive Coronary Artery Disease Open
Background: Determine the prevalence and correlates of microvascular and vasospastic angina in patients with symptoms and signs of ischemia but no obstructive coronary artery disease (INOCA). Methods: Three hundred ninety-one patients with…
View article: Scientific Business Abstracts of the 113th Annual Meeting of the Association of Physicians of Great Britain and Ireland
Scientific Business Abstracts of the 113th Annual Meeting of the Association of Physicians of Great Britain and Ireland Open
Aims: Left ventricular hypertrophy (LVH) is independently associated with adverse cardiovascular outcome. The pathophysiology of LVH development remains unclear although observational studies have reported its association with blood pressu…
View article: 50 Ischaemia and No Obstructive Coronary Artery Disease (INOCA): prevalence and predictors of coronary vasomotion disorders
50 Ischaemia and No Obstructive Coronary Artery Disease (INOCA): prevalence and predictors of coronary vasomotion disorders Open
Background Ischemia and no obstructive epicardial coronary artery disease (INOCA) is a common clinical syndrome with distinct underlying causes. Objective To evaluate the prevalence and predictors of microvascular and/or vasospastic angina…
View article: Effect of Low-Dose Intracoronary Alteplase During Primary Percutaneous Coronary Intervention on Microvascular Obstruction in Patients With Acute Myocardial Infarction
Effect of Low-Dose Intracoronary Alteplase During Primary Percutaneous Coronary Intervention on Microvascular Obstruction in Patients With Acute Myocardial Infarction Open
ClinicalTrials.gov Identifier: NCT02257294.
View article: Redefining successful primary PCI
Redefining successful primary PCI Open
No abstract available.