Peter Meiland
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View article: A unifying approach to drug-in-polymer solubility prediction: Streamlining experimental workflow and analysis
A unifying approach to drug-in-polymer solubility prediction: Streamlining experimental workflow and analysis Open
This method paper describes currently used experimental methods to predict the drug-in-polymer solubility of amorphous solid dispersions and offers a combined approach for applying the Melting-point-depression method, the Recrystallization…
A new method to determine drug-polymer solubility through enthalpy of melting and mixing Open
In this study, a new method to determine the solubility of crystalline drugs in (amorphous) polymers is proposed. The method utilizes annealing of supersaturated amorphous solid dispersions to achieve equilibrium between dissolved and recr…