Peter R. Jermain
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View article: Late radiation-related lymphopenia after prostate stereotactic body radiation therapy plus or minus supplemental pelvic irradiation
Late radiation-related lymphopenia after prostate stereotactic body radiation therapy plus or minus supplemental pelvic irradiation Open
Introduction Prior studies suggest lymphopenia following radiation therapy may impact toxicity and cancer control. Chronic radiation-related lymphopenia (RRL) has been noted in prostate cancer patients treated with conventionally fractiona…
View article: Deep learning-based cell segmentation for rapid optical cytopathology of thyroid cancer
Deep learning-based cell segmentation for rapid optical cytopathology of thyroid cancer Open
View article: PROTON FLASH IRRADIATION INDUCED DNA DOUBLE STRAND BREAKS AS REVEALED BY ATOMIC FORCE MICROSCOPY
PROTON FLASH IRRADIATION INDUCED DNA DOUBLE STRAND BREAKS AS REVEALED BY ATOMIC FORCE MICROSCOPY Open
View article: Rapid Optical Cytology with Deep Learning-Based Cell Segmentation for Diagnosis of Thyroid Lesions
Rapid Optical Cytology with Deep Learning-Based Cell Segmentation for Diagnosis of Thyroid Lesions Open
We have developed and implemented a rapid, robust, and clinically viable protocol for fluorescence polarization cytopathology of thyroid nodules. The proposed approach utilizes rapid sample preparation and automated image analysis to accur…
View article: Translational Potential of Fluorescence Polarization for Breast Cancer Cytopathology
Translational Potential of Fluorescence Polarization for Breast Cancer Cytopathology Open
Breast cancer is the most common malignancy in women. The standard of care for diagnosis involves invasive core needle biopsy followed by time-consuming histopathological evaluation. A rapid, accurate, and minimally invasive method to diag…
View article: Design and Validation of a Handheld Optical Polarization Imager for Preoperative Delineation of Basal Cell Carcinoma
Design and Validation of a Handheld Optical Polarization Imager for Preoperative Delineation of Basal Cell Carcinoma Open
Background: Accurate removal of basal cell carcinoma (BCC) is challenging due to the subtle contrast between cancerous and normal skin. A method aiding with preoperative delineation of BCC margins would be valuable. The aim of this study w…
View article: Fluorescence Polarization Imaging of Methylene Blue Facilitates Quantitative Detection of Thyroid Cancer in Single Cells
Fluorescence Polarization Imaging of Methylene Blue Facilitates Quantitative Detection of Thyroid Cancer in Single Cells Open
Background: Diagnostic accuracy of the standard of care fine-needle aspiration cytology (FNAC) remains a significant problem in thyroid oncology. Therefore, a robust and accurate method for reducing uncertainty of cytopathological evaluati…
View article: Temperature induced changes in the optical properties of skin in vivo
Temperature induced changes in the optical properties of skin in vivo Open
View article: Dual-Wavelength Optical Polarization Imaging for Detecting Skin Cancer Margins
Dual-Wavelength Optical Polarization Imaging for Detecting Skin Cancer Margins Open
Treatment of keratinocyte carcinomas requires an assessment of the extent of tumor spread. Visual delineation of tumor margins is error-prone owing to the limited contrast between cancerous and normal skin. In this contribution, we introdu…
View article: Multimodal quantitative imaging of brain cancer in cultured cells
Multimodal quantitative imaging of brain cancer in cultured cells Open
Fluorescence emission, polarization and subcellular localization of methylene blue (MB) were studied in four cancerous and two normal human brain cell lines. Fluorescence emission and polarization images were acquired and analyzed. The co-…