Peter Rocha
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View article: <i>Aspergillus fumigatus</i> effector crpA orchestrates host prostaglandin signaling to promote fungal virulence
<i>Aspergillus fumigatus</i> effector crpA orchestrates host prostaglandin signaling to promote fungal virulence Open
Conidia are the primary infection structures in Aspergillus fumigatus , the etiologic agent of aspergillosis. Here, we characterized CrpA (a c ysteine- r ich p rotein), a conidial surface-associated protein important for fungal evasion and…
View article: <i>Aspergillus fumigatus</i> secondary metabolite pyripyropene is important for the dual biofilm formation with <i>Pseudomonas aeruginosa</i>
<i>Aspergillus fumigatus</i> secondary metabolite pyripyropene is important for the dual biofilm formation with <i>Pseudomonas aeruginosa</i> Open
The human pathogenic fungus Aspergillus fumigatus establishes dual biofilm interactions in the lungs with the pathogenic bacterium Pseudomonas aeruginosa . Screening of 21 A . fumigatus null mutants revealed seven mutants (two G protein-co…
View article: Correction: Reactive oxygen species and nitric oxide imbalances lead to in vivo and in vitro arrhythmogenic phenotype in acute phase of experimental Chagas disease
Correction: Reactive oxygen species and nitric oxide imbalances lead to in vivo and in vitro arrhythmogenic phenotype in acute phase of experimental Chagas disease Open
[This corrects the article DOI: 10.1371/journal.ppat.1008379.].
View article: Reactive oxygen species and nitric oxide imbalances lead to in vivo and in vitro arrhythmogenic phenotype in acute phase of experimental Chagas disease
Reactive oxygen species and nitric oxide imbalances lead to in vivo and in vitro arrhythmogenic phenotype in acute phase of experimental Chagas disease Open
[This corrects the article DOI: 10.1371/journal.ppat.1008379.].
View article: Trypanosoma cruzi Needs a Signal Provided by Reactive Oxygen Species to Infect Macrophages
Trypanosoma cruzi Needs a Signal Provided by Reactive Oxygen Species to Infect Macrophages Open
Our results indicate a paradoxical role for ROS since modified parasites multiply better inside macrophages, but proliferation is significantly reduced when ROS is removed from the host cell. Our findings suggest that ROS can work like a s…