P.C. Sharpe
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Performance of Colorimetric Lateral Flow Immunoassays for Renal Function Evaluation with Human Serum Cystatin C Open
Chronic kidney disease (CKD) is associated with heart failure and neurological disorders. Therefore, point-of-care (POC) detection of CKD is essential, allowing disease monitoring from home and alleviating healthcare professionals’ workloa…
Development of colorimetric lateral flow assays with gold nanostructures for Cystatin C detection Open
Cystatin C (CysC) is a biomarker indicative of renal function, and its comorbidities, including heart failure. Generally, enzyme-linked immunosorbent assay (ELISA) can detect CysC in hours but requires skilled personnel, thorough reagent p…
Cystatin C as a biomarker for cardiorenal syndrome diseases quantitative diagnostics and monitoring via point-of-care Open
With heart failure (HF) and renal malfunction becoming global public health issues, there is an urgent need to monitor diseases at home or in the community. Point-of-care testing (POC) would shorten the patients waiting time compared with …
View article: Evaluation of the IgG antibody response to SARS CoV-2 infection and performance of a lateral flow immunoassay: cross-sectional and longitudinal analysis over 11 months
Evaluation of the IgG antibody response to SARS CoV-2 infection and performance of a lateral flow immunoassay: cross-sectional and longitudinal analysis over 11 months Open
Objective To evaluate the dynamics and longevity of the humoral immune response to SARS-CoV-2 infection and assess the performance of professional use of the UK-RTC AbC-19 Rapid Test lateral flow immunoassay (LFIA) for the target condition…
View article: Laboratory evaluation of SARS-CoV-2 antibodies: detectable IgG up to 20 weeks post infection
Laboratory evaluation of SARS-CoV-2 antibodies: detectable IgG up to 20 weeks post infection Open
Background The SARS-CoV-2 pandemic necessitated rapid and global responses across all areas of healthcare, including an unprecedented interest in serological immunoassays to detect antibodies to the virus. The dynamics of the immune respon…