Péter Szatmári
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View article: Changed expression of placental transporters and disrupted epigenetic patterns in a rat model of schizophrenia
Changed expression of placental transporters and disrupted epigenetic patterns in a rat model of schizophrenia Open
Introduction Generally, the pregnant women with schizophrenia have higher consumption of medicinal drugs. During pregnancy, placental ABC transporters regulate drug disposition and are involved in fetal and placental development. This stud…
View article: A qualitative study exploring youth’s experiences of hospital- and integrated community-based mental health services: the YouthCan IMPACT initiative
A qualitative study exploring youth’s experiences of hospital- and integrated community-based mental health services: the YouthCan IMPACT initiative Open
Background Approximately 20% of Canadian youth (12–25 years) experience mental health and substance use (MHSU) concerns, with the majority not receiving timely evidence-informed care. The YouthCan IMPACT study was a pragmatic randomized co…
View article: Alterations in P-glycoprotein Expression in the Placenta of Obese Rats and Humans
Alterations in P-glycoprotein Expression in the Placenta of Obese Rats and Humans Open
Obesity affects approximately 30% of pregnancies worldwide and is one of the leading metabolic disorders among pregnant women. Maternal obesity is often associated with placental dysfunction and structural alterations, which increase the r…
View article: Transdiagnostic Profiles of BOLD Signal Variability in Autism and Schizophrenia Spectrum Disorders: Associations with Cognition and Functioning
Transdiagnostic Profiles of BOLD Signal Variability in Autism and Schizophrenia Spectrum Disorders: Associations with Cognition and Functioning Open
Background Autism spectrum disorder (autism) and schizophrenia spectrum disorders (schizophrenia) exhibit overlapping social and neurocognitive impairment and considerable neurobiological heterogeneity. Blood-oxygen-level-dependent (BOLD) …
View article: Interrater Reliability and Measurement Error of the Children’s Depression Rating Scale–Revised in Adolescents
Interrater Reliability and Measurement Error of the Children’s Depression Rating Scale–Revised in Adolescents Open
View article: The association between mental health self-stigma and multiple mental health conditions: A systematic review
The association between mental health self-stigma and multiple mental health conditions: A systematic review Open
View article: Adaptation and validation of the Washington group/unicef child functioning module in a nationally representative sample of Canadian children and youth
Adaptation and validation of the Washington group/unicef child functioning module in a nationally representative sample of Canadian children and youth Open
Background The Washington Group/UNICEF Child Functioning Module (WG/UNICEF CFM) was developed to identify children and youth with disabilities by assessing functional difficulties. This study focuses on the cognitive, emotional, and behavi…
View article: Measuring functioning among youth using the Columbia impairment scale: investigating dimensionality and measurement invariance among 14–17 year olds using mental health services and their caregivers
Measuring functioning among youth using the Columbia impairment scale: investigating dimensionality and measurement invariance among 14–17 year olds using mental health services and their caregivers Open
View article: Sex‐Differential Trajectories of Domain‐Specific Associations Between Autistic Traits and Co‐Occurring Emotional‐Behavioral Concerns in Autistic Children
Sex‐Differential Trajectories of Domain‐Specific Associations Between Autistic Traits and Co‐Occurring Emotional‐Behavioral Concerns in Autistic Children Open
Assessing autistic traits alongside co‐occurring emotional/behavioral concerns (EBCs) is challenging due to their overlap in clinical presentations, which can vary by age and sex. This study aimed to investigate domain‐specific association…
View article: Comparative Analysis of Social Cognitive and Neurocognitive Performance Across Autism and Schizophrenia Spectrum Disorders
Comparative Analysis of Social Cognitive and Neurocognitive Performance Across Autism and Schizophrenia Spectrum Disorders Open
Background and Hypothesis Social cognitive and neurocognitive performance is impacted in autism and schizophrenia spectrum disorders (SSDs). Here, we compared social cognitive and neurocognitive performance across a large transdiagnostic s…
View article: Narrative enhancement and cognitive therapy for self-stigma among youth with bipolar disorder or multiple mental health conditions: protocol for a pilot randomised basket trial
Narrative enhancement and cognitive therapy for self-stigma among youth with bipolar disorder or multiple mental health conditions: protocol for a pilot randomised basket trial Open
Introduction Self-stigma occurs when individuals internalise negative stereotypes about their mental health conditions. Self-stigma is common among those with serious mental illnesses, including youth, and is considered a major barrier to …
View article: Impact of household food insecurity and nutrition on depression and anxiety symptoms among adolescents living in rural Pakistan
Impact of household food insecurity and nutrition on depression and anxiety symptoms among adolescents living in rural Pakistan Open
Background This study investigates the links between dietary diversity, food insecurity and mental health (depression and anxiety) in adolescents from rural Pakistan. Adolescence is a critical time for developing mental health disorders, y…
View article: Minimally important change on the Columbia Impairment Scale and Strengths and Difficulties Questionnaire in youths seeking mental healthcare
Minimally important change on the Columbia Impairment Scale and Strengths and Difficulties Questionnaire in youths seeking mental healthcare Open
Background Evidence-based mental health requires patient-relevant outcome data, but many indicators lack clinical meaning and fail to consider youth perceptions. The minimally important change (MIC) indicator designates change as meaningfu…
View article: Latent class analysis of actigraphy within the depression early warning (DEW) longitudinal clinical youth cohort
Latent class analysis of actigraphy within the depression early warning (DEW) longitudinal clinical youth cohort Open
Background Wearable-generated data yield objective information on physical activity and sleep variables, which, are in turn, related to the phenomenology of depression. There is a dearth of wearable-generated data regarding physical activi…
View article: Early-Onset Trajectories of Emotional Dysregulation in Autistic Children
Early-Onset Trajectories of Emotional Dysregulation in Autistic Children Open
Emotional dysregulation, in the form of frequent and severe meltdowns, irritability and impulsivity, often cause a lot of stress for children with autism spectrum disorder (ASD) and their families. Using data from the Pathways in ASD follo…
View article: The missing clinical guidance: a scoping review of care for autistic transgender and gender-diverse people
The missing clinical guidance: a scoping review of care for autistic transgender and gender-diverse people Open
This study was funded through a Canadian Institutes of Health Research Sex and Gender Science Chair program (GSB 171373) awarded to M-CL.
View article: Task-based functional neural correlates of social cognition across autism and schizophrenia spectrum disorders
Task-based functional neural correlates of social cognition across autism and schizophrenia spectrum disorders Open
Background Autism and schizophrenia spectrum disorders (SSDs) both feature atypical social cognition. Despite evidence for comparable group-level performance in lower-level emotion processing and higher-level mentalizing, limited research …
View article: Guideline for reporting systematic reviews of outcome measurement instruments (OMIs): PRISMA-COSMIN for OMIs 2024
Guideline for reporting systematic reviews of outcome measurement instruments (OMIs): PRISMA-COSMIN for OMIs 2024 Open
Purpose Although comprehensive and widespread guidelines on how to conduct systematic reviews of outcome measurement instruments (OMIs) exist, for example from the COSMIN (COnsensus-based Standards for the selection of health Measurement I…
View article: An integrated clinical approach to children at genetic risk for neurodevelopmental and psychiatric conditions: interdisciplinary collaboration and research infrastructure
An integrated clinical approach to children at genetic risk for neurodevelopmental and psychiatric conditions: interdisciplinary collaboration and research infrastructure Open
View article: Discriminative Validity and Interpretability of the Mood and Feelings Questionnaire
Discriminative Validity and Interpretability of the Mood and Feelings Questionnaire Open
Background: Using the Mood and Feelings Questionnaire (MFQ) to differentiate between depression severity levels remains unexplored. We assessed the discriminative validity of the MFQ to identify an optimal cut-off MFQ score to distinguish …
View article: Interpretation of High-Resolution Remote Sensing Data for Plio-Pleistocene Tectonic Structures Studies in the Trindade Island Volcanic Building, South Atlantic Ocean, Brazil
Interpretation of High-Resolution Remote Sensing Data for Plio-Pleistocene Tectonic Structures Studies in the Trindade Island Volcanic Building, South Atlantic Ocean, Brazil Open
Trindade Island (20°31′0’ S and 29°19′0 W) is a large alkaline volcanic edifice and is the only emerging part of the Vitória-Trindade ridge, 1140 km from the Brazilian offshore, whose summit is around 600 meters high. The lineament orienta…
View article: Adaptation and Validation of the Washington Group/UNICEF Child Functioning Module in a Nationally Representative Sample of Canadian Children and Youth
Adaptation and Validation of the Washington Group/UNICEF Child Functioning Module in a Nationally Representative Sample of Canadian Children and Youth Open
Background: The Washington Group/UNICEF Child Functioning Module (WG/UNICEF CFM) was developed to assess functional difficulties among children and youth in national household surveys. The objective of this study was to examine the latent …
View article: Gender diversity is correlated with dimensional neurodivergent traits but not categorical neurodevelopmental diagnoses in children
Gender diversity is correlated with dimensional neurodivergent traits but not categorical neurodevelopmental diagnoses in children Open
Background Gender clinic and single‐item questionnaire‐based data report increased co‐occurrence of gender diversity and neurodevelopmental conditions. The nuances of these associations are under‐studied. We used a transdiagnostic approach…
View article: Bifactor models of psychopathology using multi‐informant and multi‐instrument dimensional measures in the ABCD study
Bifactor models of psychopathology using multi‐informant and multi‐instrument dimensional measures in the ABCD study Open
Background Due to limitations of categorical definitions of mental illness, there is a need for quantitative empirical investigations of the dimensional structure of psychopathology. Using exploratory bifactor methods, this study investiga…
View article: Guidelines for Reporting Outcomes in Trial Protocols: The SPIRIT-Outcomes 2022 Extension
Guidelines for Reporting Outcomes in Trial Protocols: The SPIRIT-Outcomes 2022 Extension Open
Importance: Complete information in a trial protocol regarding study outcomes is crucial for obtaining regulatory approvals, ensuring standardized trial conduct, reducing research waste, and providing transparency of methods to facilitate …
View article: Guidelines for Reporting Outcomes in Trial Reports: The CONSORT-Outcomes 2022 Extension
Guidelines for Reporting Outcomes in Trial Reports: The CONSORT-Outcomes 2022 Extension Open
Importance: Clinicians, patients, and policy makers rely on published results from clinical trials to help make evidence-informed decisions. To critically evaluate and use trial results, readers require complete and transparent information…
View article: Mapping of Surface Radioactive Heat Production from in situ Gamma Spectrometry and Chemical Data of Exhumed Mantle Peridotites from St. Peter and St. Paul Archipelago (Equatorial Atlantic)
Mapping of Surface Radioactive Heat Production from in situ Gamma Spectrometry and Chemical Data of Exhumed Mantle Peridotites from St. Peter and St. Paul Archipelago (Equatorial Atlantic) Open
The mapping of radioactive heat production (RHP) and the respective radioactive heat flow (RHF) of Saint Peter and Saint Paul Archipelago (SPSPA), based on radioactive heat-producing elements (RPE) data from whole-rock chemical analysis an…
View article: Systematic Review: The Measurement Properties of the Suicidal Ideation Questionnaire and Suicidal Ideation Questionnaire-Jr
Systematic Review: The Measurement Properties of the Suicidal Ideation Questionnaire and Suicidal Ideation Questionnaire-Jr Open
View article: Trajectories of adaptive functioning from early childhood to adolescence in autism: Identifying turning points and key correlates of chronogeneity
Trajectories of adaptive functioning from early childhood to adolescence in autism: Identifying turning points and key correlates of chronogeneity Open
Background Previous research has demonstrated heterogeneous adaptive outcomes across the autism spectrum; however, the current literature remains limited in elucidating turning points and associated factors for longitudinal variability (ch…
View article: Effectiveness of emergency department-based and initiated youth suicide prevention interventions: A systematic review
Effectiveness of emergency department-based and initiated youth suicide prevention interventions: A systematic review Open
Objective This systematic review examined the effectiveness of Emergency Department-based and initiated youth suicide prevention interventions for suicide attempts, suicidal ideation, hospitalization, family system functioning, and other m…