Peter Venhuizen
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View article: At‐ <scp>RS31</scp> orchestrates hierarchical cross‐regulation of splicing factors and integrates alternative splicing with <scp>TOR</scp> ‐ <scp>ABA</scp> pathways
At‐ <span>RS31</span> orchestrates hierarchical cross‐regulation of splicing factors and integrates alternative splicing with <span>TOR</span> ‐ <span>ABA</span> pathways Open
Summary Alternative splicing is essential for plants, enabling a single gene to produce multiple transcript variants to boost functional diversity and fine‐tune responses to environmental and developmental cues. Arabidopsis thaliana At‐RS3…
View article: At-RS31 orchestrates hierarchical cross-regulation of splicing factors and integrates alternative splicing with TOR-ABA pathways
At-RS31 orchestrates hierarchical cross-regulation of splicing factors and integrates alternative splicing with TOR-ABA pathways Open
SUMMARY Alternative splicing is essential for plants, enabling a single gene to produce multiple transcript variants to boost functional diversity and fine-tune responses to environmental and developmental cues. At-RS31, a plant-specific s…
View article: Light regulates alternative splicing outcomes via the TOR kinase pathway
Light regulates alternative splicing outcomes via the TOR kinase pathway Open
For plants, light is the source of energy and the most relevant regulator of growth and adaptations to the environment by inducing changes in gene expression at various levels, including alternative splicing. Light-triggered chloroplast re…
View article: Xyloglucan Remodeling Defines Auxin-Dependent Differential Tissue Expansion in Plants
Xyloglucan Remodeling Defines Auxin-Dependent Differential Tissue Expansion in Plants Open
Size control is a fundamental question in biology, showing incremental complexity in plants, whose cells possess a rigid cell wall. The phytohormone auxin is a vital growth regulator with central importance for differential growth control.…
View article: FRUITFULL Is a Repressor of Apical Hook Opening in Arabidopsis thaliana
FRUITFULL Is a Repressor of Apical Hook Opening in Arabidopsis thaliana Open
Plants adjust their architecture to a constantly changing environment, requiring adaptation of differential growth. Despite their importance, molecular switches, which define growth transitions, are largely unknown. Apical hook development…
View article: A compendium of genome-wide sequence reads from NBS (nucleotide binding site) domains of resistance genes in the common potato
A compendium of genome-wide sequence reads from NBS (nucleotide binding site) domains of resistance genes in the common potato Open
SolariX is a compendium of DNA sequence tags from the nucleotide binding site (NBS) domain of disease resistance genes of the common potato, Solanum tuberosum Group Tuberosum. The sequences, which we call NBS tags, for nearly all NBS domai…
View article: A Collection of Pre-mRNA Splicing Mutants in <i>Arabidopsis thaliana</i>
A Collection of Pre-mRNA Splicing Mutants in <i>Arabidopsis thaliana</i> Open
To investigate factors influencing pre-mRNA splicing in plants, we conducted a forward genetic screen using an alternatively-spliced GFP reporter gene in Arabidopsis thaliana. This effort generated a collection of sixteen mutants impaired …
View article: VARIFI—Web-Based Automatic Variant Identification, Filtering and Annotation of Amplicon Sequencing Data
VARIFI—Web-Based Automatic Variant Identification, Filtering and Annotation of Amplicon Sequencing Data Open
Fast and affordable benchtop sequencers are becoming more important in improving personalized medical treatment. Still, distinguishing genetic variants between healthy and diseased individuals from sequencing errors remains a challenge. He…
View article: Light remote control of alternative splicing in roots through TOR kinase
Light remote control of alternative splicing in roots through TOR kinase Open
Summary For plants, light is the source of energy and the most relevant regulator of growth and adaptations to the environment by inducing changes in gene expression at various levels, including alternative splicing. Chloroplasts trigger r…
View article: PRP4KA, a Putative Spliceosomal Protein Kinase, Is Important for Alternative Splicing and Development in <i>Arabidopsis thaliana</i>
PRP4KA, a Putative Spliceosomal Protein Kinase, Is Important for Alternative Splicing and Development in <i>Arabidopsis thaliana</i> Open
Prp4 kinase (Prp4k) is the first spliceosome-associated kinase shown to regulate splicing in fungi and metazoans, but nothing is yet known about its functions in plants. Here, Kanno and Venhuizen et al. report... Splicing of precursor mess…
View article: A high quality Arabidopsis transcriptome for accurate transcript-level analysis of alternative splicing
A high quality Arabidopsis transcriptome for accurate transcript-level analysis of alternative splicing Open
Alternative splicing generates multiple transcript and protein isoforms from the same gene and thus is important in gene expression regulation. To date, RNA-sequencing (RNA-seq) is the standard method for quantifying changes in alternative…
View article: AtRTD2: A Reference Transcript Dataset for accurate quantification of alternative splicing and expression changes in<i>Arabidopsis thaliana</i>RNA-seq data
AtRTD2: A Reference Transcript Dataset for accurate quantification of alternative splicing and expression changes in<i>Arabidopsis thaliana</i>RNA-seq data Open
Background Alternative splicing is the major post-transcriptional mechanism by which gene expression is regulated and affects a wide range of processes and responses in most eukaryotic organisms. RNA-sequencing (RNA-seq) can generate genom…