Petra Krause
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View article: Editorial: Advances in Cancer Stem Cell Biology
Editorial: Advances in Cancer Stem Cell Biology Open
EDITORIAL article Front. Genet., 26 March 2021Sec. Cancer Genetics https://doi.org/10.3389/fgene.2021.655187
View article: A Population Pharmacokinetic Model of (R)‐ and (S‐) Oxybutynin and Its Active Metabolites After Oral and Intravesical Administration to Healthy Volunteers
A Population Pharmacokinetic Model of (R)‐ and (S‐) Oxybutynin and Its Active Metabolites After Oral and Intravesical Administration to Healthy Volunteers Open
Oxybutynin is a racemic anticholinergic drug used for the symptomatic treatment of detrusor overactivity. The formation of active metabolites related to tolerability problems depends on the route of administration. The objective of this ev…
View article: The Tumor Necrosis Factor Superfamily Members TNFSF14 (LIGHT), Lymphotoxin β and Lymphotoxin β Receptor Interact to Regulate Intestinal Inflammation
The Tumor Necrosis Factor Superfamily Members TNFSF14 (LIGHT), Lymphotoxin β and Lymphotoxin β Receptor Interact to Regulate Intestinal Inflammation Open
Over 1.5 million individuals in the United States are afflicted with inflammatory bowel disease (IBD). While the progression of IBD is multifactorial, chronic, unresolved inflammation certainly plays a key role. Additionally, while multipl…
View article: The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model
The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model Open
View article: Additional file 2: Supplement 2. of The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model
Additional file 2: Supplement 2. of The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model Open
Count data of relevant genes for the propagation of CMT-93 cells in the liver. Thirty-two DEGs were identified with a threshold of FDRÂ
View article: Additional file 1: Supplement 1. of The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model
Additional file 1: Supplement 1. of The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model Open
List of 119 genes associated with metastasis. The dataset was filtered using this list to identify DEGs between the CMT-93 cell line and liver metastases derived from CMT-93. Gene names and Ensembl IDs are shown in Additional file 1: Suppl…
View article: IL-10-producing intestinal macrophages prevent excessive antibacterial innate immunity by limiting IL-23 synthesis
IL-10-producing intestinal macrophages prevent excessive antibacterial innate immunity by limiting IL-23 synthesis Open
Innate immune responses are regulated in the intestine to prevent excessive inflammation. Here we show that a subset of mouse colonic macrophages constitutively produce the anti-inflammatory cytokine IL-10. In mice infected with Citrobacte…