Namki Hong
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View article: Entropy and Human Aging
Entropy and Human Aging Open
Entropy, a measure of disorder and randomness, is an essential feature of thermodynamics, chemistry, and information theory, but there has been little study of entropy in human aging. Entropy arises from random molecular interactions or ot…
View article: Serum Phosphorus Is a Fast and Highly Sensitive Marker Predictive of a Complete Cure of Tumor-Induced Osteomalacia
Serum Phosphorus Is a Fast and Highly Sensitive Marker Predictive of a Complete Cure of Tumor-Induced Osteomalacia Open
Background/Objectives: Tumor-induced osteomalacia (TIO) is a rare acquired paraneoplastic syndrome caused by phosphaturic mesenchymal tumors (PMTs). FGF23, which is overproduced by PMTs, causes hypophosphatemia and osteomalacia, ultimately…
View article: Dual-energy X-ray absorptiometry based biofidelic finite element models for simulating falls to the hip: Impact of trochanteric soft tissue thickness on fracture risk
Dual-energy X-ray absorptiometry based biofidelic finite element models for simulating falls to the hip: Impact of trochanteric soft tissue thickness on fracture risk Open
Biofidelic finite element models built using image data captures population-based differences in hip fracture risk for the three main ethnic groups in Singapore. In the absence of 3D optical scans, predicting soft tissue shapes based on wh…
View article: Spine age estimation using deep learning in lateral spine radiographs and DXA VFA to predict incident fracture and mortality
Spine age estimation using deep learning in lateral spine radiographs and DXA VFA to predict incident fracture and mortality Open
Spine age estimated from lateral spine radiographs and DXA VFAs could be associated with fracture and mortality risk. In the VERTE-X cohort (n = 10,341, derivation set) and KURE cohort (n = 3517; external test set), spine age discriminated…
View article: SAT-771 Risk stratification of atypical parathyroid tumor using transcriptome sequencing
SAT-771 Risk stratification of atypical parathyroid tumor using transcriptome sequencing Open
Disclosure: H. Park: None. M. Kim: None. S. Jo: None. G. Kim: None. J. Jeong: None. N. Hong: None. S. Kim: None. Y. Rhee: None. Context: Atypical parathyroid tumors (APTs) are a rare subtype of parathyroid neoplasms characterized by diagno…
View article: OR10-04 Evaluation of the Efficacy of ZOledronic Acid Administered Once or Twice After Different Durations of DenosuMab Treatment in Postmenopausal Women with Osteoporosis (ZOOM): A Prospective, Single-Center, Open-Label, Parallel, Phase IV Study
OR10-04 Evaluation of the Efficacy of ZOledronic Acid Administered Once or Twice After Different Durations of DenosuMab Treatment in Postmenopausal Women with Osteoporosis (ZOOM): A Prospective, Single-Center, Open-Label, Parallel, Phase IV Study Open
Disclosure: J. Park: None. S. Cho: None. N. Hong: None. Y. Rhee: None. Objectives: This study evaluates the efficacy of zoledronic acid in preventing bone loss in postmenopausal women with osteoporosis who transitioned off denosumab after …
View article: SAT-787 Lower Muscle Area and Immunosuppressive Agents are Associated with Greater Bone Loss in Liver Transplant Recipients
SAT-787 Lower Muscle Area and Immunosuppressive Agents are Associated with Greater Bone Loss in Liver Transplant Recipients Open
Disclosure: S. Baek: None. J. Park: None. S. Cho: None. N. Hong: None. E. Min: None. J. Lee: None. D. Joo: None. Y. Rhee: None. Liver transplantation is a critical treatment for end-stage liver disease, but musculoskeletal complications si…
View article: Entropy, Assessed by Homeostatic Dysregulation on Electrocardiograms Predicts Fracture and Mortality
Entropy, Assessed by Homeostatic Dysregulation on Electrocardiograms Predicts Fracture and Mortality Open
Entropy, characterized by increased disorder throughout biological systems, can be quantified by homeostatic dysregulation (HD). One potential measure of HD is the dispersion of points from a normal value, approximated at the individual le…
View article: Epidemiology and clinical outcomes of clinically suspected multiple endocrine neoplasia type 1 in South Korea: a nationwide cohort study
Epidemiology and clinical outcomes of clinically suspected multiple endocrine neoplasia type 1 in South Korea: a nationwide cohort study Open
Background Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary disorder characterized by multiorgan endocrine tumors, primarily affecting the parathyroid glands, pituitary, and pancreas. Despite its clinical significance, the e…
View article: Association Between Waist‐to‐Height Ratio Estimated Fat Mass Categories and Incident Fractures
Association Between Waist‐to‐Height Ratio Estimated Fat Mass Categories and Incident Fractures Open
Background Although obesity is a well‐known risk factor for various metabolic disorders, its impact on fracture risk remains uncertain. The inconsistency in findings may be due to the fact that most studies have relied solely on body mass …
View article: Transcriptome sequencing reveals distinct atypical parathyroid tumor subtypes
Transcriptome sequencing reveals distinct atypical parathyroid tumor subtypes Open
Atypical parathyroid tumors (APTs) are a rare subtype of parathyroid neoplasms characterized by diagnostic challenges and an uncertain prognosis. This study aimed to validate the subtypes of APTs using transcriptome sequencing. We applied …
View article: Comprehensive Evaluation of Treatment Patterns in Postmenopausal Patients with Osteoporosis without Fractures: Insights from Tertiary Care Institutions and Nationwide OMOP-CDM Data
Comprehensive Evaluation of Treatment Patterns in Postmenopausal Patients with Osteoporosis without Fractures: Insights from Tertiary Care Institutions and Nationwide OMOP-CDM Data Open
Background: Osteoporosis is a global health concern. Despite emerging treatment options for this condition, limited data are available on hospital practices in South Korea. This study addresses the need for a hospital network database that…
View article: Clinical outcomes and bone marker changes in postmenopausal women with dental implants: a one-year prospective study
Clinical outcomes and bone marker changes in postmenopausal women with dental implants: a one-year prospective study Open
View article: Correction to: Effect of anti-sclerostin antibody on orthodontic tooth movement in ovariectomized rats
Correction to: Effect of anti-sclerostin antibody on orthodontic tooth movement in ovariectomized rats Open
View article: Bisphosphonates as a Tacrolimus-Sparing Strategy in Kidney Transplantation: Insights from a Retrospective Analysis
Bisphosphonates as a Tacrolimus-Sparing Strategy in Kidney Transplantation: Insights from a Retrospective Analysis Open
View article: The Impact of the Comprehensive Real Estate Holding Tax on Asset Equity and the Rental Housing Market
The Impact of the Comprehensive Real Estate Holding Tax on Asset Equity and the Rental Housing Market Open
View article: Low Skeletal Muscle Radiodensity Predicts Response to CDK4/6 Inhibitors Plus Aromatase Inhibitors in Advanced Breast Cancer
Low Skeletal Muscle Radiodensity Predicts Response to CDK4/6 Inhibitors Plus Aromatase Inhibitors in Advanced Breast Cancer Open
Background Recent evidence indicates that a dysregulated host metabolism influences treatment outcomes in patients with breast cancer. We investigated the association of computed tomography (CT)‐derived body composition indices with therap…
View article: Digital Phenotyping of Rare Endocrine Diseases Across International Data Networks and the Effect of Granularity of Original Vocabulary
Digital Phenotyping of Rare Endocrine Diseases Across International Data Networks and the Effect of Granularity of Original Vocabulary Open
Our findings demonstrate the feasibility of developing digital phenotyping of rare endocrine diseases and highlight the importance of implementing SNOMED CT in routine clinical practice to provide granularity for research.
View article: Discriminatory Accuracy of Fracture Risk Assessment Tool in Asian Populations: A Systematic Review and Meta-Analysis
Discriminatory Accuracy of Fracture Risk Assessment Tool in Asian Populations: A Systematic Review and Meta-Analysis Open
Background: This review explores the discriminative ability of fracture risk assessment tool (FRAX) in major osteoporotic fracture (MOF) and hip fracture (HF) risk prediction and the densitometric diagnosis of osteoporosis in Asian populat…
View article: Efficacy and safety of weekly liquid alendronate in Korean postmenopausal women with osteoporosis: a 12-month, multi-center, randomized trial
Efficacy and safety of weekly liquid alendronate in Korean postmenopausal women with osteoporosis: a 12-month, multi-center, randomized trial Open
View article: Effect of anti-sclerostin antibody on orthodontic tooth movement in ovariectomized rats
Effect of anti-sclerostin antibody on orthodontic tooth movement in ovariectomized rats Open
Background This study aimed to evaluate the effect of systemically administered anti-sclerostin antibodies (Anti-Scl Ab) on orthodontic tooth movements (OTM) in an ovariectomized rat. Methods Twenty-four 12-week-old female Sprague-Dawley r…
View article: Association of Delayed Denosumab Dosing with Increased Risk of Fractures: A Population-Based Retrospective Study
Association of Delayed Denosumab Dosing with Increased Risk of Fractures: A Population-Based Retrospective Study Open
Background: Inhibitory effects of denosumab on bone remodeling are reversible and disappear once treatment is discontinued. Herein, we examined whether and to what extent delayed denosumab administration is also associated with fracture ri…
View article: Validating Machine Learning Models Against the Saline Test Gold Standard for Primary Aldosteronism Diagnosis
Validating Machine Learning Models Against the Saline Test Gold Standard for Primary Aldosteronism Diagnosis Open
View article: Nanoparticle-based itaconate treatment recapitulates low-cholesterol/low-fat diet-induced atherosclerotic plaque resolution
Nanoparticle-based itaconate treatment recapitulates low-cholesterol/low-fat diet-induced atherosclerotic plaque resolution Open
Current pharmacologic treatments for atherosclerosis do not completely protect patients; additional protection can be achieved by dietary modifications, such as a low-cholesterol/low-fat diet (LCLFD), that mediate plaque stabilization and …
View article: 12486 Clinical Manifestations And Mortality Outcomes Of Multiple Endocrine Neoplasia Type 2 Patients With Medullary Thyroid Cancer In Korea Using The National Health Insurance Service Database
12486 Clinical Manifestations And Mortality Outcomes Of Multiple Endocrine Neoplasia Type 2 Patients With Medullary Thyroid Cancer In Korea Using The National Health Insurance Service Database Open
Disclosure: Y. Hwang: None. K. Kim: None. M. Yu: None. N. Hong: None. Y. Rhee: None. Objective: Multiple Endocrine Neoplasia Type 2 (MEN2) is a rare, inherited disorder that most commonly presents as medullary thyroid carcinoma (MTC). This…
View article: 12406 Epidemiology Of Multiple Endocrine Neoplasia Type 1 In South Korea: A Nationwide Cohort Study
12406 Epidemiology Of Multiple Endocrine Neoplasia Type 1 In South Korea: A Nationwide Cohort Study Open
Disclosure: K. Kim: None. Y. Hwang: None. M. Yu: None. S. Moon: None. N. Hong: None. Y. Rhee: None. Multiple Endocrine Neoplasia Type 1 (MEN1) is one of the rarest endocrine disorders, with a scarcity of comprehensive epidemiological data …
View article: 6986 Efficacy and Safety of Weekly Liquid Alendronate Sodium Trihydrate in Korean Postmenopausal Women with Osteoporosis: A 12-Month, Multi-Center, Randomized Trial
6986 Efficacy and Safety of Weekly Liquid Alendronate Sodium Trihydrate in Korean Postmenopausal Women with Osteoporosis: A 12-Month, Multi-Center, Randomized Trial Open
Disclosure: Y. Rhee: None. S. Ahn: None. N. Hong: None. D. Seo: None. S. Hong: None. Background: Although alendronate is the most prescribed oral bisphosphonate for osteoporosis treatment, it can lead to gastrointestinal problems, impactin…
View article: 12406 Epidemiology Of Multiple Endocrine Neoplasia Type 1 In South Korea: A Nationwide Cohort Study
12406 Epidemiology Of Multiple Endocrine Neoplasia Type 1 In South Korea: A Nationwide Cohort Study Open
Disclosure: K. Kim: None. Y. Hwang: None. M. Yu: None. S. Moon: None. N. Hong: None. Y. Rhee: None. Multiple Endocrine Neoplasia Type 1 (MEN1) is one of the rarest endocrine disorders, with a scarcity of comprehensive epidemiological data …
View article: 12486 Clinical Manifestations And Mortality Outcomes Of Multiple Endocrine Neoplasia Type 2 Patients With Medullary Thyroid Cancer In Korea Using The National Health Insurance Service Database
12486 Clinical Manifestations And Mortality Outcomes Of Multiple Endocrine Neoplasia Type 2 Patients With Medullary Thyroid Cancer In Korea Using The National Health Insurance Service Database Open
Disclosure: Y. Hwang: None. K. Kim: None. M. Yu: None. N. Hong: None. Y. Rhee: None. Objective: Multiple Endocrine Neoplasia Type 2 (MEN2) is a rare, inherited disorder that most commonly presents as medullary thyroid carcinoma (MTC). This…
View article: Differential Impact of Subcutaneous and Visceral Fat on Bone Changes after Gastrectomy
Differential Impact of Subcutaneous and Visceral Fat on Bone Changes after Gastrectomy Open
Background: Osteoporosis and fragility fractures are crucial musculoskeletal complications in long-term survivors of gastric cancer. However, the relationship between changes in body composition after gastrectomy and bone loss has not been…