Phan Văn Kiệm
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View article: Psychoserpens A and B: Two New Iridoids From the Leaves of <i>Psychotria serpens</i> L. That Inhibit Nitric Oxide Production
Psychoserpens A and B: Two New Iridoids From the Leaves of <i>Psychotria serpens</i> L. That Inhibit Nitric Oxide Production Open
Psychotria serpens , a significant traditional Vietnamese plant, exhibits anti‐inflammatory properties and is clinically used to treat rheumatism and sciatica. However, its bioactive components remain poorly understood. In this study, phyt…
View article: SPIROSTAN GLYCOSIDES FROM TRIBULUS TERRESTRIS
SPIROSTAN GLYCOSIDES FROM TRIBULUS TERRESTRIS Open
Four spirostan glycosides, neohecogenin 3-O-β-D- glucopyranosyl-(1→4)-β-D-galactopyranoside (1), neohecogenin 3-O-β-D-galactopyranosyl-(1→2)-β-D- glucopyranosyl-(1→4)-β-D-galactopyranoside (2), hecogenin 3-O-β-D-galactopyranosyl-(1→2)-β-D-…
View article: Four Earlier Unidentified Compounds Isolated From <i>Zanthoxylum rhetsa</i> and Their NO Inhibitory Activity
Four Earlier Unidentified Compounds Isolated From <i>Zanthoxylum rhetsa</i> and Their NO Inhibitory Activity Open
The plant Zanthoxylum rhetsa has been used for centuries as both food and traditional medicine by the Vietnamese people to treat some diseases. Using various chromatography methods, four earlier unidentified compounds ( 1–4 ), along with e…
View article: Two Earlier Undescribed Flavanone Glycosides From the Leaves of <i>Croton dongnaiensis</i> With Their Acetylcholinesterase Inhibitory Activity
Two Earlier Undescribed Flavanone Glycosides From the Leaves of <i>Croton dongnaiensis</i> With Their Acetylcholinesterase Inhibitory Activity Open
Two undescribed flavanol glycosides ( 1 and 2 ), together with 10 known phenolic compounds ( 3 – 12 ) were isolated from the leaves of Croton dongnaiensis . Their chemical structures were determined by high‐resolution electrospray ionizati…
View article: Camehakosides A–E, Five Undescribed Acylated Oleanane Saponins From the Leaves of <i>Camellia hakodae</i> With Their α‐Glucosidase Inhibitory Activity
Camehakosides A–E, Five Undescribed Acylated Oleanane Saponins From the Leaves of <i>Camellia hakodae</i> With Their α‐Glucosidase Inhibitory Activity Open
Five undescribed acylated oleanane saponins ( 1–5 ), together with five known compounds ( 6–10 ) were isolated from the leaves of Camellia hakodae . Their chemical structures were determined by infrared, high‐resolution electrospray ioniza…
View article: Discovery of Undescribed Flavonoid and Rotenoid Derivatives From the Leaves of <i>Derris trifoliata</i> With Their Cytotoxic Activity
Discovery of Undescribed Flavonoid and Rotenoid Derivatives From the Leaves of <i>Derris trifoliata</i> With Their Cytotoxic Activity Open
Phytochemical study on the leaves of Derris trifoliata led to the isolation of five rotenoids ( 3 – 7 ) and 10 flavonoid derivatives ( 1 , 2 , 8–15 ). Three of them, (2S)‐5,7‐dihydroxy‐6‐(2‐hydroxyethyl)‐2‐(4‐hydroxyphenyl)‐8‐(3‐methylbut‐…
View article: Three New Sesquiterpenes from the Leaves of <i>Aglaia elaeagnoidea</i> with NO Inhibitory Activity
Three New Sesquiterpenes from the Leaves of <i>Aglaia elaeagnoidea</i> with NO Inhibitory Activity Open
Aglanoideas A−C ( 1 – 3 ), three undescribed sesquiterpenes and eleven known compounds ( 4 – 14 ) were isolated from the leaves of Aglaia elaeagnoidea . Their structures including absolute configurations were characterized by using IR, HR‐…
View article: The genus <i>Derris</i> Lour., a potential source of valuable biologically active ingredients
The genus <i>Derris</i> Lour., a potential source of valuable biologically active ingredients Open
This article summarizes the recent reports on the chemical components and biological activities of the genus Derris Lour. There are about 240 compounds isolated from this genus, including 31 rotenoids, 146 flavones and their derivatives (f…
View article: A new <i>cis</i>‐clerodane‐type furanoditerpenoid from the leaves of <i>Tinospora crispa</i> with inhibitory effect on LPS induced NO production in RAW 264.7 cells
A new <i>cis</i>‐clerodane‐type furanoditerpenoid from the leaves of <i>Tinospora crispa</i> with inhibitory effect on LPS induced NO production in RAW 264.7 cells Open
Three cis ‐clerodane‐type furanoditerpenoids ( 1 ‐ 3 ) including one new compound named tinocrioside D ( 1 ) together with four known compounds ( 4 ‐ 7 ) were isolated from the leaves of Tinospora crispa . Their chemical structures were de…
View article: Four New Tirucallane Triterpenoids from the Leaves of <i>Ailanthus Triphysa</i> with Anti‐Inflammatory Activities
Four New Tirucallane Triterpenoids from the Leaves of <i>Ailanthus Triphysa</i> with Anti‐Inflammatory Activities Open
Isolation and determination of three new compounds from the leaves of Ailanthus triphysa (Dennst.) Alston with their anti‐inflammatory activity. Ten tirucallane triterpenes ( 1 – 10 ) including four undescribed compounds, ailantriphysas A–…
View article: Three New Spirostan Glycosides from <i>Dracaena Cochinchinensis</i> with NO Production Inhibitory and Antimicrobial Activity
Three New Spirostan Glycosides from <i>Dracaena Cochinchinensis</i> with NO Production Inhibitory and Antimicrobial Activity Open
Three new spirostan glycosides, dracochinosides A–C ( 1 – 3 ), and four known steroidal glycosides ( 4 – 7 ) were isolated from the aerial parts of Dracaena cochinchinensis (Lour.) S.C.Chen. Their chemical structures were determined by the…
View article: Suaedamas A‐D: Four New Compounds from the Aerial Parts of <i>Suaeda maritima</i> with Inhibition of NO Production Activity
Suaedamas A‐D: Four New Compounds from the Aerial Parts of <i>Suaeda maritima</i> with Inhibition of NO Production Activity Open
Four new compounds, suaedamas A–D ( 1 – 4 ), and seven known ones ( 5 – 11 ) were isolated from the aerial parts of Suaeda maritima . Their chemical structures were evaluated by the IR, HR‐ESI‐MS, 1D‐, and 2D‐NMR, experimental and calculat…
View article: Phyllanretiosides A and B: Two Undescribed Compounds from <i>Phyllanthus Reticulatus</i> with Nitric Oxide Production Inhibition and Antimicrobial Activity
Phyllanretiosides A and B: Two Undescribed Compounds from <i>Phyllanthus Reticulatus</i> with Nitric Oxide Production Inhibition and Antimicrobial Activity Open
Phytochemical study on the methanol extract of the leaves of Phyllanthus reticulatus led to the isolation of two new compounds, phyllanretiosides A ( 1 ) and B ( 2 ) together with ten known ones ( 3 – 12 ). Their chemical structures were d…
View article: The genus <i>Aglaia</i>: Diversity in chemical structure and biological activity
The genus <i>Aglaia</i>: Diversity in chemical structure and biological activity Open
The Meliaceae family has been investigated comprehensively because of their structurally multifarious, and biologically active components. The genus Aglaia has the highest amount in this family, including around 150 species. These species …
View article: Hepatoprotective Lignan Glycosides from the Leaves and Stems of <i>Symplocos cochinchinensis</i> (Lour.) S. Moore
Hepatoprotective Lignan Glycosides from the Leaves and Stems of <i>Symplocos cochinchinensis</i> (Lour.) S. Moore Open
This study investigates Symplocos cochinchinensis (Lour.) S. Moore leaves and stems, commonly known as Symplocos, a plant indigenous to Asia renowned for its traditional use in holistic medicine. A comprehensive phytochemical analysis of S…
View article: Tributelosides A−D: Four Undescribed Spirostan Glycosides Isolated from the Branches and Leaves of <i>Tribulus terrestris</i> with Their NO Production Inhibitory Activity in LPS Activated RAW 264.7 Cells
Tributelosides A−D: Four Undescribed Spirostan Glycosides Isolated from the Branches and Leaves of <i>Tribulus terrestris</i> with Their NO Production Inhibitory Activity in LPS Activated RAW 264.7 Cells Open
Four undescribed spirostan glycosides, (25 S )‐5 α ‐spirostan‐ 12‐one‐2 α ,3 β ‐diol‐3‐ O ‐ β ‐D‐glucopyranosyl‐(1→4)‐ β ‐D‐galactopyranoside ( 1 ), (25 S )‐5 α ‐spirostan‐12‐one‐2 α ,3 β ‐diol‐3‐ O ‐ β ‐D‐galatopyranosyl‐(1→2)‐ β ‐D‐gluco…
View article: Stilbene derivatives from <i>Gnetum montanum</i> Markgr. with their xanthine oxidase inhibition activity
Stilbene derivatives from <i>Gnetum montanum</i> Markgr. with their xanthine oxidase inhibition activity Open
Phytochemical study on the methanol extract of the trunks of Gnetum montanum Markgr. led to the isolation of one new stilbene derivative, ( E )‐2′‐methoxy‐3,5,5′‐trihydroxystilbene ( 1 ) and six known compounds, lehmbachol ( 2 ), gnetulin …
View article: Four Undescribed Stilbenoid Derivatives from the Aerial Parts of <i>Dendrobium officinale</i> with their <i>α</i>‐Glucosidase and <i>α</i>‐Amylase Inhibitory Activity
Four Undescribed Stilbenoid Derivatives from the Aerial Parts of <i>Dendrobium officinale</i> with their <i>α</i>‐Glucosidase and <i>α</i>‐Amylase Inhibitory Activity Open
In this study, four undescribed bibenzyl derivatives ( 1 – 4 ), together with seven known compounds ( 5 – 11 ) were isolated from the aerial parts of Dendrobium officinale . Their chemical structures were determined to be (7’ S ,8’ S ) ‐9′…
View article: Structure, absolute configuration and cytotoxicity of compounds isolated from <i>Decaschistia harmandii</i>
Structure, absolute configuration and cytotoxicity of compounds isolated from <i>Decaschistia harmandii</i> Open
Phytochemical study of Decaschistia harmandii led to the identification of four compounds (−)‐Ampelopsin F ( 1 ), Ampelopsin ( 2 ), Rhodomyrtone ( 3 ), and Phloretin ( 4 ). The chemical structures of the compounds were determined based on …
View article: Ecdysterols and triterpene glycoside from Achyranthes aspera L. and their NO production inhibitory activity
Ecdysterols and triterpene glycoside from Achyranthes aspera L. and their NO production inhibitory activity Open
Phytochemical study on the methanolic extract of the aerial parts of Achyranthes aspera led to the isolation of six compounds including five ecdysterols, makisterone A (1), achyranthesterone A (2), 24(28)-dehydromakisterone A (3), podecdys…
View article: Megastigmanes and other constituents from <i>Achyranthes aspera</i>
Megastigmanes and other constituents from <i>Achyranthes aspera</i> Open
A new megastigmane glycoside, (3 S ,5 R ,6 R ,9 S )‐6,9‐epoxiionane‐3,5‐diol 3‐ O ‐ β ‐primeveroside ( 1 ) together with 7 compounds ( 2–8 ) were isolated from Achyranthes aspera L. The chemical structures were elucidated through 1D‐, 2D‐ …
View article: Chemical constituents of <i>Syzygium cerasiforme</i> leaves and their nitric oxide inhibitory activity in LPS‐activated RAW264.7 cells
Chemical constituents of <i>Syzygium cerasiforme</i> leaves and their nitric oxide inhibitory activity in LPS‐activated RAW264.7 cells Open
A phytochemical study of the methanolic extract of Syzygium cerasiforme leaves led to the isolation of seven compounds ( 1 – 7 ). Their chemical structures were identified as benzyl‐6ʹ‐ O ‐galloyl‐β‐ d ‐glucopyranoside ( 1 ), 3‐methoxy‐4‐h…
View article: Undescribed sesquiterpene-diterpene heterodimers from the fruits of Aphanamixis polystachya selectively modulate inflammatory markers in RAW 264.7 cells
Undescribed sesquiterpene-diterpene heterodimers from the fruits of Aphanamixis polystachya selectively modulate inflammatory markers in RAW 264.7 cells Open
Aphanapolystachones A-C (1-3), three undescribed sesquiterpene-diterpene heterodimers, were obtained from the fruits of Aphanamixis polystachya. Their structures and absolute configurations were identified by extensive analysis of HR-ESI-M…
View article: Discovery of new triterpene glycosides from <i>Dendrobium officinale</i> with their α-glucosidase and α-amylase inhibitory activity
Discovery of new triterpene glycosides from <i>Dendrobium officinale</i> with their α-glucosidase and α-amylase inhibitory activity Open
Seven new oleanane saponins were discovered from Dendrobium officinale . These saponins containing 29-noroleana-12,20(30)-dien-28-oic acid framework, caffeoyl, and coumaroyl moieties potentially inhibited α-glucosidase and α-amylase activi…
View article: New diterpene lactone derivatives from <i>Aphanamixis polystachya</i> leaves inhibit nitric oxide production in RAW 264.7 cells
New diterpene lactone derivatives from <i>Aphanamixis polystachya</i> leaves inhibit nitric oxide production in RAW 264.7 cells Open
Five new acyclic diterpene lactone derivatives containing two rare structural fragments a γ / δ -lactone and a furan-3-one from Aphanamixis polystachya . They inhibited NO production in LPS activated RAW264.7 cells with IC 50 values of 16.…
View article: Four New Steroidal Saponins from the Roots of <i>Dracaena cambodiana</i> with NO Production Inhibition Activity in LPS Activated RAW 264.7 Cells
Four New Steroidal Saponins from the Roots of <i>Dracaena cambodiana</i> with NO Production Inhibition Activity in LPS Activated RAW 264.7 Cells Open
Seven steroidal saponins including three new 16,23‐cyclocholestanes ( 1 ‐ 3 ) and one new pregane ( 4 ) were isolated from the roots of Dracaena cambodiana Pierre ex Gagnep. Their chemical structures were elucidated to be (23 R ,25 R )‐26‐…
View article: Secondary metabolites from Sarcosperma kontumense
Secondary metabolites from Sarcosperma kontumense Open
Six urs-ketone triterpenes (1 - 6) and two flavonoids (7, 8) from the leaves of Sarcosperma kontumense Gagnep. ex Aubrév., were isolated. Their chemical structures were elucidated as 2α,3α,19α,23-tetrahydroxy-13,27-cyclours-11-en-28-oic ac…
View article: A New Guaianolide-type Sesquiterpenoid and Xanthine Oxidase Inhibitory Activity from Chrysanthemum sinense Flowers
A New Guaianolide-type Sesquiterpenoid and Xanthine Oxidase Inhibitory Activity from Chrysanthemum sinense Flowers Open
The ethanol extract of C. sinense flowers was found to inhibit xanthine oxidase with IC 50 value of 8.20 ± 1.36 µg/mL. Using various chromatographic methods, one new guaianolide- type sesquiterpenoid, chrysanoside K ( 1 ), along with seven…
View article: Four Steroidal Saponins from the Trunks of <i>Dracaena cambodiana</i> with Inhibition of NO Production in LPS Activated RAW264.7 Cells
Four Steroidal Saponins from the Trunks of <i>Dracaena cambodiana</i> with Inhibition of NO Production in LPS Activated RAW264.7 Cells Open
Dracaena cambodiana Pierre ex Gagnep. is well known as a medicinal plant and widely distributed in Vietnam. Phytochemical investigation on the trunks of D. cambodiana lead to the isolation of four undescribed compounds ( 1 – 4 ) together w…
View article: Carabrachiatanins A and B: Two New Phenylpropanoid-Substituted Catechins of <i>Carallia brachiata</i> Merr
Carabrachiatanins A and B: Two New Phenylpropanoid-Substituted Catechins of <i>Carallia brachiata</i> Merr Open
Objectives: Carallia brachiata Merr. is a Vietnamese medicinal plant, used to treat mouth ulcers, tongue sores, sore throats, and malaria. This paper focuses on the chemical constituents of C. brachiata and their inhibition of NO productio…