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View article: 1086 NKTR-288, a polymer-conjugated interferon gamma mutein for the treatment of solid tumors
1086 NKTR-288, a polymer-conjugated interferon gamma mutein for the treatment of solid tumors Open
Background Interferon gamma (IFNg) cytokine induces cellular antigen presentation and has great potential in cancer treatment through enhancement of tumor antigen specific cytotoxic T cell response. However, the unfavorable pharmacokinetic…