Philip Brainin
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Predicting heart failure readmission and all-cause mortality in patients with acute heart failure: a simple predischarge risk score Open
Introduction Predischarge risk stratification of patients hospitalized for acute heart failure (AHF) could facilitate tailored treatment and follow-up, however, simple scores to predict short-term risk for HF readmission or death are lacki…
Potential role of transthoracic echocardiography for screening LV systolic dysfunction in patients with a history of dengue infection. A cross-sectional and cohort study and review of the literature Open
Background Dengue virus can affect the cardiovascular system and men may be at higher risk of severe complications than women. We hypothesized that clinical dengue virus (DENV) infection could induce myocardial alterations of the left vent…
Is self-rated health associated with cardiovascular risk factors and disease in a low-income setting? A cross-sectional study from the Amazon Basin of Brazil Open
Objective Prior studies have suggested that self-rated health may be a useful indicator of cardiovascular disease. Consequently, we aimed to assess the relationship between self-rated health, cardiovascular risk factors and subclinical car…
Prevalence and Dynamic Changes in Lung Ultrasound Findings among Adults with Uncomplicated Malaria and Controls in the Amazon Basin, Brazil Open
Malaria patients are at risk of cardiopulmonary complications but diagnosis and management can be difficult in resource-limited settings. B-lines on lung ultrasound (LUS) mark changes in lung density; however, little is known about their r…
Patient reported health status and cardiovascular risk factors in a remote area of South America: a cross-sectional study Open
Background Several studies have indicated that self-perception of health is related to cardiovascular disease. Despite cardiovascular disease is the leading cause of mortality in South America, the relationship between patient reported hea…
Diagnostic value of electrocardiograms to identify pericardial effusion in acute malaria: a cross-sectional study Open
Background Patients with acute malaria are at risk of pericarditis and may benefit from timely identification of pericardial effusion. However, diagnostic imaging tools, such as echocardiography, are not always available in malaria endemic…
B-lines by lung ultrasound is associated with pulmonary symptoms and cardiac function in acute malaria: a prospective cohort study Open
Background Malaria patients are at risk of cardiopulmonary complications, but diagnosis and management are difficult in resource limited environments. B-lines by lung ultrasonography (LUS) can identify pulmonary alterations, however, littl…
Myocardial Postsystolic Shortening and Early Systolic Lengthening: Current Status and Future Directions Open
The concept of paradoxical myocardial deformation, commonly referred to as postsystolic shortening and early systolic lengthening, was originally described in the 1970s when assessed by invasive cardiac methods, such as ventriculograms, in…
Heart failure associated with imported malaria: a nationwide Danish cohort study Open
Aims Despite adequate treatment, recent studies have hypothesized that malaria may affect long‐term cardiovascular function. We aimed to investigate the long‐term risk of cardiovascular events and death in individuals with a history of imp…
Levels of hepatitis B antibody titers are affected by age and doses gap time in children from a high endemic area of the western Amazon Open
Background Despite completion of the vaccine schedule for hepatitis B virus (HBV), children may display levels of HBV surface antibodies (anti-HBs) that are considered inadequate for sufficient protection (<10 IU/L). Aims Our aim was to in…
Prevalence of Cardiovascular Complications in Malaria: A Systematic Review and Meta-Analysis Open
Recent studies have suggested that malaria may affect the cardiovascular system. The aim of this systematic review and meta-analysis was to determine the prevalence of cardiovascular complications in symptomatic malaria patients. We search…
View article: Prognostic utility of early systolic lengthening by speckle tracking in patients undergoing coronary artery bypass graft
Prognostic utility of early systolic lengthening by speckle tracking in patients undergoing coronary artery bypass graft Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): The Independent Research Fund Denmark Background Early systolic lengthening (ESL), a paradoxical stretch of myocardial fibers…
Body mass index and B‐lines on lung ultrasonography in chronic and acute heart failure Open
Aims Increased body mass index (BMI) is common in heart failure (HF) patients and is associated with lower levels of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP). We evaluated the influence of BMI on lung ultrasonography (LUS) find…
Early Systolic Lengthening in Patients With ST‐Segment–Elevation Myocardial Infarction: A Novel Predictor of Cardiovascular Events Open
Background Early systolic lengthening ( ESL ) may occur in ischemic myocardial segments with reduced contractile force. We sought to evaluate the prognostic potential of ESL in patients with ST ‐segment–elevation myocardial infarction trea…
Prognostic utility of diastolic dysfunction and speckle tracking echocardiography in heart failure with reduced ejection fraction Open
Aims We hypothesized that grading of diastolic dysfunction (DDF) according to two DDF grading algorithms and strain imaging yields prognostic information on all‐cause mortality in patients with heart failure with reduced ejection fraction …
Ability of non-physicians to perform and interpret lung ultrasound: A systematic review Open
Background: Lung ultrasound is a useful tool in the assessment of pulmonary congestion in heart failure that is typically performed and interpreted by physicians at the point-of-care. Aims: To investigate the ability of nurses, students, a…
The cardiac isovolumetric contraction time is an independent predictor of incident atrial fibrillation and adverse outcomes following first atrial fibrillation event in the general population Open
Aims Colour tissue Doppler imaging (TDI) M-mode through the mitral leaflet is an easy and precise method to obtain cardiac time intervals including the isovolumic contraction time (IVCT), isovolumic relaxation time (IVRT), and ejection tim…
P2748The cardiac isovolumic contraction time predicts heart failure in the general population Open
Echocardiography in ventricular function 563 to age and DM at baseline.Further including EF as a covariate does not improve the multivariable model (P=0.1)Univariate Full adjustments HR (95% CI) P value HR (95% CI) P value Age 1.1 (1-1.1)<…
Postsystolic Shortening by Speckle Tracking Echocardiography Is an Independent Predictor of Cardiovascular Events and Mortality in the General Population Open
Background Postsystolic shortening ( PSS ) has been proposed as a novel marker of contractile dysfunction in the myocardium. Our objective was to assess the prognostic potential of PSS on cardiovascular events and death in the general popu…