Philip Rauch
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View article: Early Prediction of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage Using a Machine Learning Model and Interactive Web Application
Early Prediction of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage Using a Machine Learning Model and Interactive Web Application Open
Background: Cerebral vasospasm is a frequent and severe complication after aneurysmal subarachnoid hemorrhage (aSAH), often causing delayed cerebral ischemia (DCI) and poor outcomes. Despite progress in neurocritical care, early vasospasm …
View article: Intrathecal Triamcinolone for Lumbar Degenerative Disease: A Single-Center Retrospective Cohort of 499 Patients
Intrathecal Triamcinolone for Lumbar Degenerative Disease: A Single-Center Retrospective Cohort of 499 Patients Open
Background/Objectives: While epidural and periradicular corticosteroid injections are well-established treatments for degenerative spinal conditions, intrathecal administration of glucocorticoids remains uncommon and under-researched. To o…
View article: Accuracy of Navigated High-Speed Drill-Assisted Cervical and Upper Thoracic Pedicle Screw Placement—A Single Center Experience with 1112 Pedicle Screws
Accuracy of Navigated High-Speed Drill-Assisted Cervical and Upper Thoracic Pedicle Screw Placement—A Single Center Experience with 1112 Pedicle Screws Open
Background/Objectives: While biomechanically superior, cervical pedicle screw placement is technically challenging, and therefore typically performed only in centers with the aid of navigation. The purpose of this study was to analyze the …
View article: Rupture risk assessment for AComA aneurysms with morphological, hemodynamic and structural mechanical analysis
Rupture risk assessment for AComA aneurysms with morphological, hemodynamic and structural mechanical analysis Open
Introduction The Anterior Communicating Artery complex (AComA) is one of the most common intracranial aneurysms locations. Accurate rupture risk assessment in patients with cerebral aneurysms is essential for optimizing treatment decisions…
View article: Low-grade gliomas do not grow along white matter tracts: evidence from quantitative imaging
Low-grade gliomas do not grow along white matter tracts: evidence from quantitative imaging Open
Low-grade gliomas are infiltrative brain tumors that can lead to significant neurological deficits due to their invasive nature. The prevailing belief is that low-grade gliomas primarily disseminate along white matter tracts, but quantitat…
View article: Personalized targeted glioblastoma therapies by ex vivo drug screening: Study protocol of the Advanced brain Tumor TheRApy Clinical Trial (ATTRACT)
Personalized targeted glioblastoma therapies by ex vivo drug screening: Study protocol of the Advanced brain Tumor TheRApy Clinical Trial (ATTRACT) Open
Background Novel approaches to guide personalized treatment in glioblastoma are urgently needed. Given the poor predictive value of genetic biomarkers in glioblastoma, we are conducting a prospective clinical trial to investigate the novel…
View article: Challenging frontiers in neuroplastic cranial reconstruction: addressing neurosurgical wound healing complications through interdisciplinary collaboration – an observational study
Challenging frontiers in neuroplastic cranial reconstruction: addressing neurosurgical wound healing complications through interdisciplinary collaboration – an observational study Open
View article: Microsurgical Clipping of Unruptured Middle Cerebral Artery Bifurcation Aneurysms: A Single-Center Experience
Microsurgical Clipping of Unruptured Middle Cerebral Artery Bifurcation Aneurysms: A Single-Center Experience Open
Background/Objectives: Microsurgical clipping has traditionally been considered a standard treatment for middle cerebral artery (MCA) aneurysms. Recently, a caseload reduction related to improved endovascular treatment options has occurred…
View article: Machine Learning–Based Prediction of Chronic Shunt-Dependent Hydrocephalus After Spontaneous Subarachnoid Hemorrhage
Machine Learning–Based Prediction of Chronic Shunt-Dependent Hydrocephalus After Spontaneous Subarachnoid Hemorrhage Open
ML models, including logistic regression, demonstrate strong predictive capability for early chronic shunt-dependent hydrocephalus following spontaneous SAH, which may potentially contribute to more timely shunt placement interventions. Th…
View article: Decompressive craniectomy plus best medical treatment versus best medical treatment alone for spontaneous severe deep supratentorial intracerebral haemorrhage: a randomised controlled clinical trial
Decompressive craniectomy plus best medical treatment versus best medical treatment alone for spontaneous severe deep supratentorial intracerebral haemorrhage: a randomised controlled clinical trial Open
Swiss National Science Foundation, Swiss Heart Foundation, Inselspital Stiftung, and Boehringer Ingelheim.
View article: From molecular signatures to radiomics: tailoring neurooncological strategies through forecasting of glioma growth
From molecular signatures to radiomics: tailoring neurooncological strategies through forecasting of glioma growth Open
OBJECTIVE Contemporary oncological paradigms for adjuvant treatment of low- and intermediate-grade gliomas are often guided by a limited array of parameters, overlooking the dynamic nature of the disease. The authors’ aim was to develop a …
View article: Machine learning based outcome prediction of microsurgically treated unruptured intracranial aneurysms
Machine learning based outcome prediction of microsurgically treated unruptured intracranial aneurysms Open
View article: Deep learning-assisted radiomics facilitates multimodal prognostication for personalized treatment strategies in low-grade glioma
Deep learning-assisted radiomics facilitates multimodal prognostication for personalized treatment strategies in low-grade glioma Open