Philip van Eijndhoven
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View article: No Effects of rTMS on Performance Monitoring and Attentional Bias in Patients With Alcohol Use Disorder: A Pilot Study
No Effects of rTMS on Performance Monitoring and Attentional Bias in Patients With Alcohol Use Disorder: A Pilot Study Open
Repetitive transcranial magnetic stimulation (rTMS) presents a promising approach for treating patients with alcohol use disorder (AUD). However, its neuropsychological working mechanisms are to be elucidated. Therefore, we investigated th…
View article: Effects of electroconvulsive therapy on hippocampal longitudinal axis and its association with cognitive side effects
Effects of electroconvulsive therapy on hippocampal longitudinal axis and its association with cognitive side effects Open
Background Electroconvulsive therapy (ECT)-mediated hippocampal volumetric increase is consistently reported, though its clinical relevance remains debated. This study evaluates if ECT-related cognitive side effects are associated with reg…
View article: Utilizing repetitive transcranial magnetic stimulation in the management of gambling disorder in Indonesia: protocol for a pilot and feasibility study
Utilizing repetitive transcranial magnetic stimulation in the management of gambling disorder in Indonesia: protocol for a pilot and feasibility study Open
Gambling disorder (GD) has emerged as a significant concern in Indonesia, particularly due to the rise in internet-based gambling during the pandemic and the limited availability of treatment options and support services for affected indiv…
View article: Characterizing Functional Connectivity Gradients for the Hippocampus-Amygdala Complex in Healthy and Psychiatric Cohorts
Characterizing Functional Connectivity Gradients for the Hippocampus-Amygdala Complex in Healthy and Psychiatric Cohorts Open
The hippocampus and amygdala play essential roles in human cognition and emotion, through their extensive connectivity with other brain regions and close interaction between them. Uncovering the functional organization of the hippocampus–a…
View article: Functional network connectivity deviation is associated with transdiagnostic symptomatology
Functional network connectivity deviation is associated with transdiagnostic symptomatology Open
With the use of normative modelling, we could detect differences in functional brain connectivity in patients as compared to controls, even in a highly heterogeneous and comorbid patient sample. Additionally, transdiagnostic approaches, li…
View article: Comparison of 5-Day Multidaily Neuronavigated Theta-Burst Sessions With 6-Week Standard Repetitive Transcranial Magnetic Stimulation (the Dutch Depression Outcome Trial): Protocol for a Randomized Controlled Trial
Comparison of 5-Day Multidaily Neuronavigated Theta-Burst Sessions With 6-Week Standard Repetitive Transcranial Magnetic Stimulation (the Dutch Depression Outcome Trial): Protocol for a Randomized Controlled Trial Open
Background Novel therapies are crucial for patients with major depressive disorder, as more than 33% of patients do not respond to first-line treatments. A promising novel treatment strategy is an intensive 5-day course of personalized, fu…
View article: A comparison between rTMS and antidepressant medication on depressive symptom clusters in treatment-resistant depression
A comparison between rTMS and antidepressant medication on depressive symptom clusters in treatment-resistant depression Open
View article: Aberrant Aversive Learning Signals in the Habenula in Remitted Patients With Recurrent Depression
Aberrant Aversive Learning Signals in the Habenula in Remitted Patients With Recurrent Depression Open
The increased habenula activity during aversive learning, particularly during the expectation of punishment, together with decreased functional habenula-ventral tegmental area connectivity in remitted patients with MDD, reflect hypersensit…
View article: Anhedonia as a Transdiagnostic Symptom Across Psychological Disorders: A Network Approach
Anhedonia as a Transdiagnostic Symptom Across Psychological Disorders: A Network Approach Open
The results suggest that anhedonia may serve as a common underlying transdiagnostic psychopathology feature, predictive of the severity of symptom clusters of depression, AS, ADHD, and ASD. Thus, anhedonia may be associated with the high c…
View article: Measuring Self-Referent Memory Bias as Marker for Depression: Overview, New Insights, and Recommendations
Measuring Self-Referent Memory Bias as Marker for Depression: Overview, New Insights, and Recommendations Open
Negative self-referent memory bias (the preferential memory for negative self-referent information) is a well-known symptom of depression and a risk factor for its development, maintenance, and recurrence. Evidence shows its potential as a…
View article: The relationship between electric field strength induced by electroconvulsive therapy and cognitive and antidepressant outcomes
The relationship between electric field strength induced by electroconvulsive therapy and cognitive and antidepressant outcomes Open
View article: Long-term (cost-)effectiveness of rTMS compared to antidepressant medication: results of a randomized controlled trial with twelve months follow-up
Long-term (cost-)effectiveness of rTMS compared to antidepressant medication: results of a randomized controlled trial with twelve months follow-up Open
View article: Impact of titration, dosing-factor and pulse-width on electroconvulsive therapy remission rates in depression
Impact of titration, dosing-factor and pulse-width on electroconvulsive therapy remission rates in depression Open
View article: Predicting Treatment Response to ECT for depression leveraging Spatial Patterns for Discriminative Estimation
Predicting Treatment Response to ECT for depression leveraging Spatial Patterns for Discriminative Estimation Open
View article: Relapse prevention strategies after successful electroconvulsive therapy for major depressive disorder: a systematic literature review and Delphi expert opinion
Relapse prevention strategies after successful electroconvulsive therapy for major depressive disorder: a systematic literature review and Delphi expert opinion Open
View article: Dutch-Depression Outcome trial comparing 5 day multi-daily neuronavigated Theta burst sessions with 6 weeks standard rTMS (D-DOTT study), multicentre, randomized, controlled trial
Dutch-Depression Outcome trial comparing 5 day multi-daily neuronavigated Theta burst sessions with 6 weeks standard rTMS (D-DOTT study), multicentre, randomized, controlled trial Open
View article: More rTMS pulses or more sessions? The impact on treatment outcome for treatment resistant depression
More rTMS pulses or more sessions? The impact on treatment outcome for treatment resistant depression Open
View article: Cost‐Effectiveness of <scp>rTMS</scp> as a Next Step in Antidepressant Non‐Responders: A Randomized Comparison With Current Antidepressant Treatment Approaches
Cost‐Effectiveness of <span>rTMS</span> as a Next Step in Antidepressant Non‐Responders: A Randomized Comparison With Current Antidepressant Treatment Approaches Open
Background Although repetitive transcranial magnetic stimulation (rTMS) is an effective and commonly used treatment option for treatment‐resistant depression, its cost‐effectiveness remains much less studied. In particular, the comparative…
View article: More <scp>rTMS</scp> pulses or more sessions? The impact on treatment outcome for treatment resistant depression
More <span>rTMS</span> pulses or more sessions? The impact on treatment outcome for treatment resistant depression Open
Background Repetitive transcranial magnetic stimulation (rTMS) is effective for treatment‐resistant depression (TRD). Optimal rTMS parameters remain unclear, especially whether number of sessions or amount of pulses contribute more to trea…
View article: A prediction model for electroconvulsive therapy effectiveness in patients with major depressive disorder from the Dutch ECT Consortium (DEC)
A prediction model for electroconvulsive therapy effectiveness in patients with major depressive disorder from the Dutch ECT Consortium (DEC) Open
View article: Childhood adversity, stress reactivity, and structural brain measures in stress‐related/neurodevelopmental disorders, and their comorbidity: A large transdiagnostic cross‐sectional study
Childhood adversity, stress reactivity, and structural brain measures in stress‐related/neurodevelopmental disorders, and their comorbidity: A large transdiagnostic cross‐sectional study Open
Childhood adversity (CA), including childhood adverse life events, increases the risk for development of psychiatric disorders later in life. Both CA and psychiatric disorders are associated with structural brain changes and dysfunctional …
View article: Electroconvulsive therapy and cognitive performance from the Global ECT MRI Research Collaboration
Electroconvulsive therapy and cognitive performance from the Global ECT MRI Research Collaboration Open
View article: The Sensitivity of the Mini-Mental State Examination to Detect Objective Cognitive Side Effects Induced by Electroconvulsive Therapy: Results From the Dutch ECT Consortium
The Sensitivity of the Mini-Mental State Examination to Detect Objective Cognitive Side Effects Induced by Electroconvulsive Therapy: Results From the Dutch ECT Consortium Open
View article: The gut-microbiome in adult Attention-deficit/hyperactivity disorder - A Meta-analysis
The gut-microbiome in adult Attention-deficit/hyperactivity disorder - A Meta-analysis Open
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition that persists into adulthood in the majority of individuals. While the gut-microbiome seems to be relevant for ADHD, the few publications on gut-micro…
View article: rTMS as a Next Step in Antidepressant Nonresponders: A Randomized Comparison With Current Antidepressant Treatment Approaches
rTMS as a Next Step in Antidepressant Nonresponders: A Randomized Comparison With Current Antidepressant Treatment Approaches Open
In a sample of patients with moderately treatment-resistant depression, rTMS was more effective in reducing depressive symptoms than a switch of antidepressant medication. In addition, the findings suggest that the choice of treatment may …
View article: Dissecting task-based fMRI activity using normative modelling: an application to the Emotional Face Matching Task
Dissecting task-based fMRI activity using normative modelling: an application to the Emotional Face Matching Task Open
Functional neuroimaging has contributed substantially to understanding brain function but is dominated by group analyses that index only a fraction of the variation in these data. It is increasingly clear that parsing the underlying hetero…
View article: Precision Electroconvulsive Therapy (PET) project: tackling (cost) effectiveness and patient’s perspectives
Precision Electroconvulsive Therapy (PET) project: tackling (cost) effectiveness and patient’s perspectives Open
Background Depression puts a great burden on both patients, relatives and society as a whole. Electroconvulsive therapy (ECT) is regarded as a safe and effective treatment for severe and chronic depressive episodes, even when other interve…
View article: Autistic and non-autistic individuals show the same amygdala activity during emotional face processing
Autistic and non-autistic individuals show the same amygdala activity during emotional face processing Open
View article: How executive control and emotional reactivity influence coping strategies in psychiatric patients during the COVID-19 pandemic
How executive control and emotional reactivity influence coping strategies in psychiatric patients during the COVID-19 pandemic Open
Background During times of environmental challenges, adaptive coping strategies are essential to maintain mental health. Coping relies on executive control, which is often impaired in individuals with psychiatric disorders. Furthermore, em…
View article: Pre-treatment predictors of cognitive side-effects after treatment with electroconvulsive therapy in patients with depression: A multicenter study
Pre-treatment predictors of cognitive side-effects after treatment with electroconvulsive therapy in patients with depression: A multicenter study Open
Our findings show that verbal fluency and memory retention are temporarily affected immediately after ECT. Younger patients may be more susceptible to experiencing these acute cognitive side-effects, which seems to be mostly due to a more …