Philipp Roberts
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View article: Diagnostic performance of corneal epithelium- and Bowman’s layer thickness mapping in patients with unilateral Keratoconus
Diagnostic performance of corneal epithelium- and Bowman’s layer thickness mapping in patients with unilateral Keratoconus Open
View article: Real-Life Results after the Administration of a Single 0.19 mg Fluocinolone Acetonide (ILUVIEN<sup>®</sup>) Implant in Patients with Refractory Diabetic Macular Edema
Real-Life Results after the Administration of a Single 0.19 mg Fluocinolone Acetonide (ILUVIEN<sup>®</sup>) Implant in Patients with Refractory Diabetic Macular Edema Open
Introduction: The aim of this study was to evaluate real-life data on the functional and anatomical outcome of intravitreal fluocinolone acetonide (FAc) in patients with refractory diabetic macular edema (DME). Methods: Retrospective study…
View article: Structure-Function Correlation of Retinal Fibrosis in Eyes with Neovascular Age-Related Macular Degeneration
Structure-Function Correlation of Retinal Fibrosis in Eyes with Neovascular Age-Related Macular Degeneration Open
Purpose: To assess retinal function in areas of presumed fibrosis due to neovascular age-related macular degeneration (nAMD), using multimodal imaging and structure-function correlation. Design: Cross-sectional observational study. Methods…
View article: Non-invasive quantification of corneal vascularization using anterior segment optical coherence tomography angiography
Non-invasive quantification of corneal vascularization using anterior segment optical coherence tomography angiography Open
View article: Automated inter-device 3D OCT image registration using deep learning and retinal layer segmentation
Automated inter-device 3D OCT image registration using deep learning and retinal layer segmentation Open
Optical coherence tomography (OCT) is the most widely used imaging modality in ophthalmology. There are multiple variations of OCT imaging capable of producing complementary information. Thus, registering these complementary volumes is des…
View article: Characteristics of Henle’s fiber layer in healthy and glaucoma eyes assessed by polarization-sensitive optical coherence tomography
Characteristics of Henle’s fiber layer in healthy and glaucoma eyes assessed by polarization-sensitive optical coherence tomography Open
Using conventional optical coherence tomography (OCT), it is difficult to image Henle fibers (HF) due to their low backscattering potential. However, fibrous structures exhibit form birefringence, which can be exploited to visualize the pr…
View article: Akanthamöbenkeratitiden in Jugendlichen mit Orthokeratologielinsen
Akanthamöbenkeratitiden in Jugendlichen mit Orthokeratologielinsen Open
Zusammenfassung Hintergrund Durch die rasant steigende Prävalenz der Myopie kommen zunehmend progressionshemmende Verfahren zum Einsatz. Auch die Orthokeratologie, basierend auf dem Ansatz des peripheren Defokus, erlebt eine Renaissance. D…
View article: Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view
Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view Open
We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization cau…
View article: Correlation of vascular and fluid‐related parameters in neovascular age‐related macular degeneration using deep learning
Correlation of vascular and fluid‐related parameters in neovascular age‐related macular degeneration using deep learning Open
Purpose To identify correlations between the vascular characteristics of macular neovascularization (MNV) obtained by optical coherence tomography angiography (OCTA) and distinct retinal fluid volumes in neovascular age‐related macular deg…
View article: Baseline predictors for subretinal fibrosis in neovascular age-related macular degeneration
Baseline predictors for subretinal fibrosis in neovascular age-related macular degeneration Open
To find baseline predictors for subretinal fibrosis (SF) in neovascular age-related macular degeneration (nAMD). Forty-five eyes of 45 participants with treatment-naïve nAMD were consecutively enrolled and treated according to a standardiz…
View article: Morphologic and Microvascular Differences Between Macular Neovascularization With and Without Subretinal Fibrosis
Morphologic and Microvascular Differences Between Macular Neovascularization With and Without Subretinal Fibrosis Open
This study points out imaging biomarkers in patients with SF, which may help identifying high-risk patients.
View article: Using polarization-sensitive OCT to detect and quantify fibrotic lesions in the human retina
Using polarization-sensitive OCT to detect and quantify fibrotic lesions in the human retina Open
View article: Does retinal fluid correlate with OCTA characteristics of choroidal neovascular membranes
Does retinal fluid correlate with OCTA characteristics of choroidal neovascular membranes Open
View article: Identification and quantification of fibrotic areas in the human retina using polarization-sensitive OCT
Identification and quantification of fibrotic areas in the human retina using polarization-sensitive OCT Open
Subretinal fibrosis is one of the most prevalent causes of blindness in the elderly population, but a true gold standard to objectively diagnose fibrosis is still lacking. Since fibrotic tissue is birefringent, it can be detected by polari…
View article: Quantification of Fluid Resolution and Visual Acuity Gain in Patients With Diabetic Macular Edema Using Deep Learning
Quantification of Fluid Resolution and Visual Acuity Gain in Patients With Diabetic Macular Edema Using Deep Learning Open
ClinicalTrials.gov Identifier: NCT01627249.
View article: The broad spectrum of application of optical coherence tomography angiography to the anterior segment of the eye in inflammatory conditions: a review of the literature
The broad spectrum of application of optical coherence tomography angiography to the anterior segment of the eye in inflammatory conditions: a review of the literature Open
View article: Selective differentiation of RPE, fibrosis and choroidal neovascularization (CNV) – a multimodal imaging study
Selective differentiation of RPE, fibrosis and choroidal neovascularization (CNV) – a multimodal imaging study Open
View article: How reliable is the clinical diagnosis of subretinal fibrosis in neovascular age-related macular degeneration?
How reliable is the clinical diagnosis of subretinal fibrosis in neovascular age-related macular degeneration? Open
View article: Identification and Quantification of the Angiofibrotic Switch in Neovascular AMD
Identification and Quantification of the Angiofibrotic Switch in Neovascular AMD Open
SHRM volume decreases significantly under anti-VEGF therapy. However, lesions unresponsive to therapy may progress to fibrosis as early as 3 months. Reduction in SHRM thickness may be a prognostic marker for treatment response.
View article: Detection of the angiofibrotic switch in neovascular AMD: A quantitative analysis
Detection of the angiofibrotic switch in neovascular AMD: A quantitative analysis Open
View article: Importance of Considering the Middle Capillary Plexus on OCT Angiography in Diabetic Retinopathy
Importance of Considering the Middle Capillary Plexus on OCT Angiography in Diabetic Retinopathy Open
OCTA parameters in the MCP and DCP displayed parallel changes with DR progression, different from the SCP, emphasizing the importance of physiologic considerations in the retinal capillaries. Thus, segmentation protocols that include the M…
View article: Quantifying Microvascular Abnormalities With Increasing Severity of Diabetic Retinopathy Using Optical Coherence Tomography Angiography
Quantifying Microvascular Abnormalities With Increasing Severity of Diabetic Retinopathy Using Optical Coherence Tomography Angiography Open
Retinal and choriocapillaris vascular nonperfusion in OCTA is correlated significantly with disease severity in eyes with DR. Higher flow in the SCP may be an early marker of diabetic microvascular changes before clinical signs of DR. The …
View article: Quantifying Microvascular Abnormalities with Increasing Disease Severity in Diabetes Mellitus
Quantifying Microvascular Abnormalities with Increasing Disease Severity in Diabetes Mellitus Open
View article: Anterior Segment Optical Coherence Tomography Angiography for Identification of Iris Vasculature and Staging of Iris Neovascularization: A Pilot Study
Anterior Segment Optical Coherence Tomography Angiography for Identification of Iris Vasculature and Staging of Iris Neovascularization: A Pilot Study Open
This pilot clinical study showed that OCTA for imaging of the iris vasculature in health and disease is highly dependent on iris pigmentation. Fine, clinically invisible iris vessels can be visualized by OCTA in the very early stages as we…
View article: Geographic Atrophy and Foveal-Sparing Changes Related to Visual Acuity in Patients With Dry Age-Related Macular Degeneration Over Time
Geographic Atrophy and Foveal-Sparing Changes Related to Visual Acuity in Patients With Dry Age-Related Macular Degeneration Over Time Open
GA and FS changed inversely over time. In general, FS highly correlated with BCVA, while GA progression correlated with the central 3-mm FS regression, but not with BCVA. A threshold in GA and FS area could be determined for BCVA necessary…
View article: SEMIAUTOMATED QUANTITATIVE APPROACH TO CHARACTERIZE TREATMENT RESPONSE IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION
SEMIAUTOMATED QUANTITATIVE APPROACH TO CHARACTERIZE TREATMENT RESPONSE IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION Open
Purpose: To perform a quantitative study of the vascular microstructure in actively treated choroidal neovascularization by optical coherence tomographic angiography. Methods: Patients undergoing individualized anti–vascular endothelial gr…
View article: Automated identification and quantification of subretinal fibrosis in neovascular age-related macular degeneration using polarization-sensitive optical coherence tomography
Automated identification and quantification of subretinal fibrosis in neovascular age-related macular degeneration using polarization-sensitive optical coherence tomography Open
View article: Evaluation of choriocapillaris (CC) density in geographic atrophy (GA) due to age-related macular degeneration (AMD) in a multimodal imaging approach including optical coherence tomography angiography (OCTA)
Evaluation of choriocapillaris (CC) density in geographic atrophy (GA) due to age-related macular degeneration (AMD) in a multimodal imaging approach including optical coherence tomography angiography (OCTA) Open
View article: Chorioretinal Lesions in a Case of Melanoma-Associated Retinopathy Treated With Pembrolizumab
Chorioretinal Lesions in a Case of Melanoma-Associated Retinopathy Treated With Pembrolizumab Open
Immune checkpoint inhibitors, which are now being used more commonly for patients with advanced stages of melanoma, can exacerbate autoimmune diseases in patients with underlying clinical or latent autoimmunity. Clinicians should be aware …
View article: Automated Identification and Quantification of Subretinal Fibrosis in Neovascular Age-Related Macular Degeneration Using Polarization-Sensitive OCT
Automated Identification and Quantification of Subretinal Fibrosis in Neovascular Age-Related Macular Degeneration Using Polarization-Sensitive OCT Open
Using PS-OCT, subretinal fibrosis can be identified as an intrinsically birefringent structure and can be segmented based solely on tissue-specific contrast. Polarization-sensitive OCT offers a unique method to identify clinically relevant…