Maurizio Schmid
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View article: The intracellular domains of the DSL ligands Serrate and Delta provide different activities
The intracellular domains of the DSL ligands Serrate and Delta provide different activities Open
Endocytosis of the ligands is a central requirement for the correct activation of the Notch-signalling pathway. It is initiated by E3-ligase mediated ubiquitylation (ubi) of the intracellular domain (ICD) of the ligands on lysine (K). In D…
View article: Changes in Aortic Centerline Length and Curvature Predict Aortic Diameter Growth in Chronic Type B Aortic Dissection
Changes in Aortic Centerline Length and Curvature Predict Aortic Diameter Growth in Chronic Type B Aortic Dissection Open
Objective Aortic diameter is the primary metric used to trigger surgical intervention in chronic Type B aortic dissection (TBAD) This study investigates the correlation between diameter growth and changes in aortic centerline length, curva…
View article: The Impact of Human-Robot Collaboration Levels on Postural Stability During Working Tasks Performed While Standing: Experimental Study
The Impact of Human-Robot Collaboration Levels on Postural Stability During Working Tasks Performed While Standing: Experimental Study Open
Background The integration of collaborative robots (cobots) in industrial settings has the potential to enhance worker safety and efficiency by improving postural control and reducing biomechanical risk. Understanding the specific impacts …
View article: Comparative Approach to Performance Estimation of Pulsed Wave Doppler Equipment Based on Kiviat Diagram
Comparative Approach to Performance Estimation of Pulsed Wave Doppler Equipment Based on Kiviat Diagram Open
Quality assessment of ultrasound medical systems is a demanding task due to the high number of parameters to quantify their performance: in the present study, a Kiviat diagram-based integrated approach was proposed to effectively combine t…
View article: Using Adaptive Surface EMG Envelope Extraction for Onset Detection: A Preliminary Study on Upper Limb Amputees
Using Adaptive Surface EMG Envelope Extraction for Onset Detection: A Preliminary Study on Upper Limb Amputees Open
Surface electromyography is a valid and widely used tool for the characterization and the intention of human movement in healthy and pathological subjects; in particular, the thorough identification of the transient phase of EMG activity i…
View article: Intelligent Human–Computer Interaction: Combined Wrist and Forearm Myoelectric Signals for Handwriting Recognition
Intelligent Human–Computer Interaction: Combined Wrist and Forearm Myoelectric Signals for Handwriting Recognition Open
Recent studies have highlighted the possibility of using surface electromyographic (EMG) signals to develop human–computer interfaces that are also able to recognize complex motor tasks involving the hand as the handwriting of digits. Howe…
View article: Machine learning to detect, stage and classify diseases and their symptoms based on inertial sensor data: a mapping review
Machine learning to detect, stage and classify diseases and their symptoms based on inertial sensor data: a mapping review Open
This article presents a systematic review aimed at mapping the literature published in the last decade on the use of machine learning (ML) for clinical decision-making through wearable inertial sensors. The review aims to analyze the trend…
View article: Modalities of sequential human robot collaboration trigger different modifications of trunk oscillations
Modalities of sequential human robot collaboration trigger different modifications of trunk oscillations Open
Introduction Human robot collaboration is quickly gaining importance in the robotics and ergonomics fields due to its ability to reduce biomechanical risk on the human operator while increasing task efficiency. The performance of the colla…
View article: Novel quality assessment protocol based on Kiviat diagram for pulsed wave Doppler diagnostic systems: first results
Novel quality assessment protocol based on Kiviat diagram for pulsed wave Doppler diagnostic systems: first results Open
Ultrasound (US) systems are routinely and extensively used in several medical fields despite the lack of an internationally accepted quality standard for their testing.One crucial aspect for Quality Assessment (QA) protocols is the need to…
View article: A Comparative Study on Depth of Penetration Measurements in Diagnostic Ultrasounds Through the Adaptive SNR Threshold Method
A Comparative Study on Depth of Penetration Measurements in Diagnostic Ultrasounds Through the Adaptive SNR Threshold Method Open
Depth of penetration (DOP) has been investigated in the scientific literature as an informative parameter able to monitor over time both the sensitivity and the general performance of ultrasound (US) diagnostic systems. In common practice,…
View article: Use of a modified SIR-V model to quantify the effect of vaccination strategies on hospital demand during the Covid-19 pandemic
Use of a modified SIR-V model to quantify the effect of vaccination strategies on hospital demand during the Covid-19 pandemic Open
A novel compartmental model that includes vaccination strategy, permanence in hospital wards and tracing of infected individuals has been implemented to forecast hospital overload caused by COVID-19 pandemics in Italy. The model parameters…
View article: Doppler flow phantom failure detection by combining empirical mode decomposition and independent component analysis with short time Fourier transform
Doppler flow phantom failure detection by combining empirical mode decomposition and independent component analysis with short time Fourier transform Open
Nowadays, objective protocols and criteria for the monitoring of phantoms failures are still lacking in literature, despite their technical limitations. In such a context, the present work aims at providing an improvement of a previously p…
View article: A preliminary approach based on numerical simulations for the design of a PWV-Varying arterial simulator
A preliminary approach based on numerical simulations for the design of a PWV-Varying arterial simulator Open
Nowadays, in both scientific and medical communities, Pulse Wave Velocity (PWV) is commonly considered as a predicting factor of cardiovascular diseases. Such issue leads to the necessity of accurate PWV measurements as PWV non-local asses…
View article: Smartphone-Based Answering to School Subject Questions Alters Gait in Young Digital Natives
Smartphone-Based Answering to School Subject Questions Alters Gait in Young Digital Natives Open
Smartphone texting while walking is a very common activity among people of different ages, with the so-called "digital natives" being the category most used to interacting with an electronic device during daily activities, mostly for texti…
View article: The Influence of Different Levels of Cognitive Engagement on the Seated Postural Sway
The Influence of Different Levels of Cognitive Engagement on the Seated Postural Sway Open
In this paper, we introduced and tested a new system based on a sensorized seat, to evaluate the sitting dynamics and sway alterations caused by different cognitive engagement conditions. An office chair was equipped with load cells, and a…
View article: Lifting Activity Assessment Using Kinematic Features and Neural Networks
Lifting Activity Assessment Using Kinematic Features and Neural Networks Open
Work-related low-back disorders (WLBDs) can be caused by manual lifting tasks. Wearable devices used to monitor these tasks can be one possible way to assess the main risk factors for WLBDs. This study aims at analyzing the sensitivity of …
View article: Prosocial Virtual Reality, Empathy, and EEG Measures: A Pilot Study Aimed at Monitoring Emotional Processes in Intergroup Helping Behaviors
Prosocial Virtual Reality, Empathy, and EEG Measures: A Pilot Study Aimed at Monitoring Emotional Processes in Intergroup Helping Behaviors Open
During a non-invasive procedure, participants both helped and helped by a confederate with features that create social distance (membership in an ethnic outgroup or another social group). For this purpose, we created a set of virtual scena…
View article: Optimizing the Scale of a Wavelet-Based Method for the Detection of Gait Events from a Waist-Mounted Accelerometer under Different Walking Speeds
Optimizing the Scale of a Wavelet-Based Method for the Detection of Gait Events from a Waist-Mounted Accelerometer under Different Walking Speeds Open
The accurate and reliable extraction of specific gait events from a single inertial sensor at waist level has been shown to be challenging. Among several techniques, a wavelet-based method for initial contact (IC) and final contact (FC) es…
View article: Automated Segmentation of Colorectal Tumor in 3D MRI Using 3D Multiscale Densely Connected Convolutional Neural Network
Automated Segmentation of Colorectal Tumor in 3D MRI Using 3D Multiscale Densely Connected Convolutional Neural Network Open
The main goal of this work is to automatically segment colorectal tumors in 3D T2-weighted (T2w) MRI with reasonable accuracy. For such a purpose, a novel deep learning-based algorithm suited for volumetric colorectal tumor segmentation is…
View article: IMU-Based Classification of Parkinson's Disease From Gait: A Sensitivity Analysis on Sensor Location and Feature Selection
IMU-Based Classification of Parkinson's Disease From Gait: A Sensitivity Analysis on Sensor Location and Feature Selection Open
Inertial measurement units (IMUs) have a long-lasting popularity in a variety of industrial applications from navigation systems to guidance and robotics. Their use in clinical practice is now becoming more common, thanks to miniaturizatio…
View article: Thermal Energy Harvesting on the Bodily Surfaces of Arms and Legs through a Wearable Thermo-Electric Generator
Thermal Energy Harvesting on the Bodily Surfaces of Arms and Legs through a Wearable Thermo-Electric Generator Open
This work analyzes the results of measurements on thermal energy harvesting through a wearable Thermo-electric Generator (TEG) placed on the arms and legs. Four large skin areas were chosen as locations for the placement of the TEGs. In or…
View article: Effect of Task Failure on Intermuscular Coherence Measures in Synergistic Muscles
Effect of Task Failure on Intermuscular Coherence Measures in Synergistic Muscles Open
The term “task failure” describes the point when a person is not able to maintain the level of force required by a task. As task failure approaches, the corticospinal command to the muscles increases to maintain the required level of force…
View article: Correction: Gait parameters are differently affected by concurrent smartphone-based activities with scaled levels of cognitive effort
Correction: Gait parameters are differently affected by concurrent smartphone-based activities with scaled levels of cognitive effort Open
[This corrects the article DOI: 10.1371/journal.pone.0185825.].
View article: Gait parameters are differently affected by concurrent smartphone-based activities with scaled levels of cognitive effort
Gait parameters are differently affected by concurrent smartphone-based activities with scaled levels of cognitive effort Open
[This corrects the article DOI: 10.1371/journal.pone.0185825.].
View article: USING PVDF FILMS AS FLEXIBLE PIEZOELECTRIC GENERATORS FOR BIOMECHANICAL ENERGY HARVESTING
USING PVDF FILMS AS FLEXIBLE PIEZOELECTRIC GENERATORS FOR BIOMECHANICAL ENERGY HARVESTING Open
In this paper, a commercial polymeric piezoelectric film, the polyvinylidene fluoride (PVDF) was used to harvest electrical energy during the execution of five locomotion activities (walking, going down and up the stairs, jogging and runni…