Philipp Töpfer
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View article: Childhood maltreatment and risk of metabolic dysfunction-associated steatotic liver disease – Evidence of sex-specific associations in the general population
Childhood maltreatment and risk of metabolic dysfunction-associated steatotic liver disease – Evidence of sex-specific associations in the general population Open
These results suggest sex differences in the association between CM and objective serum and imaging markers of MASLD in adulthood. For men especially, a history of CM-exposure may increase risk of developing MASLD in adulthood.
View article: Central obesity and fat-free mass are associated with a larger spleen volume in the general population
Central obesity and fat-free mass are associated with a larger spleen volume in the general population Open
Background and aim: As the spleen plays a significant role in immunity, the aim was to investigate the associations of different body composition markers derived from various sources with spleen volume in a general population sample. Mater…
View article: Sex-specific associations of childhood maltreatment with obesity-related traits - The Study of Health in Pomerania (SHIP)
Sex-specific associations of childhood maltreatment with obesity-related traits - The Study of Health in Pomerania (SHIP) Open
Results suggest that associations between CM-exposure and obesity-related traits in adulthood are primarily present in women. This may have implications for sex-specific obesity-related cardiometabolic risk after CM.
View article: Unpredictable Maternal Behavior and Infant Emotional Reactivity in the Context of High Maternal Adversity
Unpredictable Maternal Behavior and Infant Emotional Reactivity in the Context of High Maternal Adversity Open
BackgroundWomen in low- and middle-income countries (LMIC) are at heightened risk of experiencing childhood maltreatment, with potential consequences for their offspring. Recent research, mostly conducted in high-income western countries, …
View article: Unpredictable Maternal Behavior and Infant Emotional Reactivity in the Context of High Maternal Adversity
Unpredictable Maternal Behavior and Infant Emotional Reactivity in the Context of High Maternal Adversity Open
BackgroundWomen in low- and middle-income countries (LMIC) are at heightened risk of experiencing childhood maltreatment, with potential consequences for their offspring. Recent research, mostly conducted in high-income western countries, …
View article: Major depression recurrence is associated with differences in obesity-related traits in women, but not in men
Major depression recurrence is associated with differences in obesity-related traits in women, but not in men Open
Background Obesity-related cardiometabolic comorbidity is common in major depressive disorder (MDD). However, sex differences and MDD recurrence may modify the MDD-obesity-link. Methods Sex-specific associations of MDD recurrence (single […
View article: Representing Sex and Gender Information in Biomedical Research
Representing Sex and Gender Information in Biomedical Research Open
In medicine and biomedical research, sex- and gender-related aspects are ubiquitous. If not considered adequately, a lower quality of research data can be expected together with a lower generalizability of study results with real-world set…
View article: The role of functional oxytocin receptor gene variants in the intergenerational transmission of the effects of maternal childhood maltreatment
The role of functional oxytocin receptor gene variants in the intergenerational transmission of the effects of maternal childhood maltreatment Open
Objective: Women exposed to childhood maltreatment (CM) are more likely to exhibit insensitive parenting, which may have consequences for their offspring´s development. Variation in the Oxytocin-receptor gene (OXTR) moderates risk of CM-as…