Philippe Carpentier
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View article: HFB3: an axial HFB solver with Gogny forces using a 2-center HO basis (C++/Python)
HFB3: an axial HFB solver with Gogny forces using a 2-center HO basis (C++/Python) Open
View article: Atomic resolution structures of the methane-activating enzyme in anaerobic methanotrophy reveal extensive post-translational modifications
Atomic resolution structures of the methane-activating enzyme in anaerobic methanotrophy reveal extensive post-translational modifications Open
View article: Studies of the membrane‐bound flavocytochrome <scp>MsrQ</scp> flavin mononucleotide (<scp>FMN</scp>)‐binding site reveal an unexpected ubiquinone cofactor
Studies of the membrane‐bound flavocytochrome <span>MsrQ</span> flavin mononucleotide (<span>FMN</span>)‐binding site reveal an unexpected ubiquinone cofactor Open
The methionine sulfoxide reductase PQ system (MsrPQ) is a newly identified type of bacterial methionine sulfoxide reductase (Msr) involved in the repair of periplasmic methionine residues that have been oxidized by hypochlorous acid. MsrP,…
View article: An asymmetric fission island driven by shell effects in light fragments
An asymmetric fission island driven by shell effects in light fragments Open
Nuclear fission leads to the splitting of a nucleus into two fragments 1,2 . Studying the distribution of the masses and charges of the fragments is essential for establishing the fission mechanisms and refining the theoretical models 3,4 …
View article: Current and future perspectives for structural biology at the Grenoble EPN campus: a comprehensive overview
Current and future perspectives for structural biology at the Grenoble EPN campus: a comprehensive overview Open
The European Photon and Neutron campus in Grenoble is a unique site, encompassing the European Synchrotron Radiation Facility Extremely Brilliant Source, the Institut Laue–Langevin, the European Molecular Biology Laboratory and the Institu…
View article: Atomic resolution structures of the methane-activating enzyme in anaerobic methanotrophy reveal extensive post-translational modifications.
Atomic resolution structures of the methane-activating enzyme in anaerobic methanotrophy reveal extensive post-translational modifications. Open
Anaerobic methanotrophic archaea (ANME) are crucial to planetary carbon cycling. They oxidise methane in anoxic niches by transferring electrons directly to nitrate or metal oxides and alternatively to sulfate-reducing bacteria. Due to the…
View article: Correction: A sequential model of the contribution of preschool fluid and crystallized cognitive abilities to later school achievement
Correction: A sequential model of the contribution of preschool fluid and crystallized cognitive abilities to later school achievement Open
[This corrects the article DOI: 10.1371/journal.pone.0276532.].
View article: Light-Activated Artificial CO<sub>2</sub>-Reductase: Structure and Activity
Light-Activated Artificial CO<sub>2</sub>-Reductase: Structure and Activity Open
Light-dependent reduction of carbon dioxide (CO2) into value-added products can be catalyzed by a variety of molecular complexes. Here we report a rare example of a structurally characterized artificial enzyme, resulting from th…
View article: Substrate-dependent oxidative inactivation of a W-dependent formate dehydrogenase involving selenocysteine displacement
Substrate-dependent oxidative inactivation of a W-dependent formate dehydrogenase involving selenocysteine displacement Open
Metal-dependent formate dehydrogenases are very promising targets for enzyme optimization and design of bio-inspired catalysts for CO 2 reduction, towards novel strategies for climate change mitigation. For effective application of these e…
View article: The High-Pressure Freezing Laboratory for Macromolecular Crystallography (HPMX), an ancillary tool for the macromolecular crystallography beamlines at the ESRF
The High-Pressure Freezing Laboratory for Macromolecular Crystallography (HPMX), an ancillary tool for the macromolecular crystallography beamlines at the ESRF Open
This article describes the High-Pressure Freezing Laboratory for Macromolecular Crystallography (HPMX) at the ESRF, and highlights new and complementary research opportunities that can be explored using this facility. The laboratory is ded…
View article: Substrate-dependent oxidative inactivation of a W-dependent formate dehydrogenase involving selenocysteine displacement
Substrate-dependent oxidative inactivation of a W-dependent formate dehydrogenase involving selenocysteine displacement Open
Our study shows, at near-atomic resolution, how W- Dv FdhAB inactivates over time when exposed to either of its substrates and O 2 .
View article: Stereotactic Intracavitary Irradiation for Cystic Craniopharyngiomas with Rhenium-186
Stereotactic Intracavitary Irradiation for Cystic Craniopharyngiomas with Rhenium-186 Open
Objective The intracavitary irradiation of cystic tumors has been used as a therapeutic alternative modality in the management of cystic craniopharyngiomas. In the present study, we review our experience, considering the technical issues, …
View article: Mechanistic and functional aspects of the Ruminococcin C sactipeptide isoforms
Mechanistic and functional aspects of the Ruminococcin C sactipeptide isoforms Open
View article: Light-Driven Hydrogen Evolution Reaction Catalyzed by a Molybdenum–Copper Artificial Hydrogenase
Light-Driven Hydrogen Evolution Reaction Catalyzed by a Molybdenum–Copper Artificial Hydrogenase Open
Orange protein (Orp) is a small bacterial metalloprotein of unknown function that harbors a unique molybdenum/copper (Mo/Cu) heterometallic cluster, [S2MoS2CuS2MoS2]3-. In this paper, …
View article: Evolutionary adaptation from hydrolytic to oxygenolytic catalysis
Evolutionary adaptation from hydrolytic to oxygenolytic catalysis Open
Protein fold adaptation to novel enzymatic reactions is a fundamental evolutionary process. Cofactor-independent oxygenases degrading N -heteroaromatic substrates belong to the α/β-hydrolase (ABH) fold superfamily that typically does not c…
View article: Structural and Biochemical Characterization of Mycobacterium tuberculosis Zinc SufU-SufS Complex
Structural and Biochemical Characterization of Mycobacterium tuberculosis Zinc SufU-SufS Complex Open
Iron-sulfur (Fe-S) clusters are inorganic prosthetic groups in proteins composed exclusively of iron and inorganic sulfide. These cofactors are required in a wide range of critical cellular pathways. Iron-sulfur clusters do not form sponta…
View article: The SUF machinery from Mycobacterium tuberculosis as a new target for antitubercular drugs
The SUF machinery from Mycobacterium tuberculosis as a new target for antitubercular drugs Open
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View article: Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the α/β-hydrolase fold
Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the α/β-hydrolase fold Open
We report how the common α/β-hydrolase architecture and its simple catalytic machinery have been adapted to accomplish spin-restricted metal-independent oxygenation.
View article: A sequential model of the contribution of preschool fluid and crystallized cognitive abilities to later school achievement
A sequential model of the contribution of preschool fluid and crystallized cognitive abilities to later school achievement Open
The present study documented in two distinct population-based samples the contribution of preschool fluid and crystallized cognitive abilities to school achievement in primary school and examined the mediating role of crystallized abilitie…
View article: A miniature airlock system to aid the cryo-cooling of protein crystals grown under anoxic conditions
A miniature airlock system to aid the cryo-cooling of protein crystals grown under anoxic conditions Open
Crystallographic studies of structures and mechanisms of dioxygen-employing enzymes or oxygen-sensitive proteins usually require these molecules to be prepared and crystallized under anoxic conditions in gloveboxes. Handling, cryo-cooling …
View article: High-pressure crystallography shows noble gas intervention into protein-lipid interaction and suggests a model for anaesthetic action
High-pressure crystallography shows noble gas intervention into protein-lipid interaction and suggests a model for anaesthetic action Open
View article: LEAFY protein crystals with a honeycomb structure as a platform for selective preparation of outstanding stable bio-hybrid materials
LEAFY protein crystals with a honeycomb structure as a platform for selective preparation of outstanding stable bio-hybrid materials Open
Crystals of the LEAFY protein showing a regular honeycomb architecture were used as modular platform for the preparation of a highly robustness ruthenium-based bio-hybrid material which was fully characterized by spectroscopic means and LC…
View article: Structural, biochemical and functional analyses of tRNA-monooxygenase enzyme MiaE from Pseudomonas putida provide insights into tRNA/MiaE interaction
Structural, biochemical and functional analyses of tRNA-monooxygenase enzyme MiaE from Pseudomonas putida provide insights into tRNA/MiaE interaction Open
MiaE (2-methylthio-N6-isopentenyl-adenosine37-tRNA monooxygenase) is a unique non-heme diiron enzyme that catalyzes the O2-dependent post-transcriptional allylic hydroxylation of a hypermodified nucleotide 2-methylthio-N6-isopentenyl-adeno…
View article: Raw diffraction data for [NiFeSe] hydrogenase G491A variant pressurized with O2 gas - dataset G491A-O2-LD
Raw diffraction data for [NiFeSe] hydrogenase G491A variant pressurized with O2 gas - dataset G491A-O2-LD Open
Diffraction data measured at ESRF beamline ID30B on April 8, 2018. Image files are uploaded in blocks of gzip-compressed cbf files.
View article: Raw diffraction data for [NiFeSe] hydrogenase G491A variant pressurized with O2 gas - dataset G491A-O2
Raw diffraction data for [NiFeSe] hydrogenase G491A variant pressurized with O2 gas - dataset G491A-O2 Open
Diffraction data measured at ESRF beamline ID30A-3 on September 27, 2017. N.B. Image files 1416-1419 are damaged and cannot be used for integration.
View article: Molecular mechanism of light-driven sodium pumping
Molecular mechanism of light-driven sodium pumping Open
View article: ID30A-3 (MASSIF-3) – a beamline for macromolecular crystallography at the ESRF with a small intense beam
ID30A-3 (MASSIF-3) – a beamline for macromolecular crystallography at the ESRF with a small intense beam Open
ID30A-3 (or MASSIF-3) is a mini-focus (beam size 18 µm × 14 µm) highly intense (2.0 × 10 13 photons s −1 ), fixed-energy (12.81 keV) beamline for macromolecular crystallography (MX) experiments at the European Synchrotron Radiation Facilit…
View article: Molecular mechanism of light-driven sodium pumping
Molecular mechanism of light-driven sodium pumping Open
Microbial rhodopsins appeared to be the most abundant light-harvesting proteins on the Earth and are the major contributes to the solar energy captured in the sea. They possess highly diverse biological functions. Explosion of research on …
View article: Raw diffraction data for [NiFeSe] hydrogenase pressurized with Kr gas - dataset wtKr1A
Raw diffraction data for [NiFeSe] hydrogenase pressurized with Kr gas - dataset wtKr1A Open
Diffraction data measured at ESRF beamline ID29 on October 2, 2017. Image files are uploaded in blocks of gzip-compressed cbf files.
View article: Raw diffraction data for [NiFeSe] hydrogenase G491A variant pressurized with Kr gas - dataset G491A-Kr
Raw diffraction data for [NiFeSe] hydrogenase G491A variant pressurized with Kr gas - dataset G491A-Kr Open
Diffraction data measured at ESRF beamline ID30A-3 on September 27, 2017.