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View article: Proteomics of the Oomycete Phytophthora parasitica Strain INRA 310
Proteomics of the Oomycete Phytophthora parasitica Strain INRA 310 Open
The phytopathogen Phytophthora parasitica, from the Oomycetes class, known to be the tobacco black shank agent, can induce devastating diseases in various crop, plant and forest ecosystems. The genus Phytophthora has been studied at the ce…
View article: Incomplete tricarboxylic acid cycle and proton gradient in <i>Pandoravirus massiliensis</i> : is it still a virus?
Incomplete tricarboxylic acid cycle and proton gradient in <i>Pandoravirus massiliensis</i> : is it still a virus? Open
The discovery of Acanthamoeba polyphaga Mimivirus, the first isolated giant virus of amoeba, challenged the historical hallmarks defining a virus. Giant virion sizes are known to reach up to 2.3 µm, making them visible by optical microscop…
View article: Generation of Infectious Mimivirus Virions Through Inoculation of Viral DNA Within Acanthamoeba castellanii Shows Involvement of Five Proteins, Essentially Uncharacterized
Generation of Infectious Mimivirus Virions Through Inoculation of Viral DNA Within Acanthamoeba castellanii Shows Involvement of Five Proteins, Essentially Uncharacterized Open
One of the most curious findings associated with the discovery of Acanthamoeba polyphaga mimivirus (APMV) was the presence of many proteins and RNAs within the virion. Although some hypotheses on their role in Acanthamoeba infection have b…
View article: Human galectin-1 and galectin-3 promote <i>Tropheryma whipplei</i> infection
Human galectin-1 and galectin-3 promote <i>Tropheryma whipplei</i> infection Open
Tropheryma whipplei, is an actinobacterium that causes different infections in humans, including Whipple's disease. The bacterium infects and replicates in macrophages, leading to a Th2-biased immune response. Previous studies have …
View article: Proteomics and Lipidomics Investigations to Decipher the Behavior of Willaertia magna C2c Maky According to Different Culture Modes
Proteomics and Lipidomics Investigations to Decipher the Behavior of Willaertia magna C2c Maky According to Different Culture Modes Open
Willaertia magna C2c Maky is a free-living amoeba that has demonstrated its ability to inhibit the intracellular multiplication of some Legionella pneumophila strains, which are pathogenic bacteria inhabiting the aquatic environment. The A…
View article: Tricarboxylic acid cycle and proton gradient in<i>Pandoravirus massiliensis</i>: Is it still a virus?
Tricarboxylic acid cycle and proton gradient in<i>Pandoravirus massiliensis</i>: Is it still a virus? Open
Since the discovery of Acanthamoeba polyphaga Mimivirus, the first giant virus of amoeba, the historical hallmarks defining a virus have been challenged. Giant virion sizes can reach up to 2.3 µm, making them visible by optical microscopy.…
View article: Yaravirus: A novel 80-nm virus infecting <i>Acanthamoeba castellanii</i>
Yaravirus: A novel 80-nm virus infecting <i>Acanthamoeba castellanii</i> Open
Significance Most of the known viruses of amoeba have been seen to share some features that eventually prompted authors to classify them into common evolutionary groups. Here we describe Yaravirus, an entity that could represent either the…
View article: Insight into the Lifestyle of Amoeba Willaertia magna during Bioreactor Growth Using Transcriptomics and Proteomics
Insight into the Lifestyle of Amoeba Willaertia magna during Bioreactor Growth Using Transcriptomics and Proteomics Open
Willaertia magna C2c maky is a thermophilic free-living amoeba strain that showed ability to eliminate Legionella pneumophila, a pathogenic bacterium living in the aquatic environment. The amoeba industry has proposed the use of Willaertia…
View article: Lactonase Specificity Is Key to Quorum Quenching in Pseudomonas aeruginosa
Lactonase Specificity Is Key to Quorum Quenching in Pseudomonas aeruginosa Open
The human opportunistic pathogen Pseudomonas aeruginosa orchestrates the expression of many genes in a cell density-dependent manner by using quorum sensing (QS). Two acyl-homoserine lactones (AHLs) are involved in QS circuits and c…
View article: A mysterious 80 nm amoeba virus with a near-complete “ORFan genome” challenges the classification of DNA viruses
A mysterious 80 nm amoeba virus with a near-complete “ORFan genome” challenges the classification of DNA viruses Open
Here we report the discovery of Yaravirus, a new lineage of amoebal virus with a puzzling origin and phylogeny. Yaravirus presents 80 nm-sized particles and a 44,924 bp dsDNA genome encoding for 74 predicted proteins. More than 90% (68) of…
View article: Rapid MALDI-TOF MS identification of commercial truffles
Rapid MALDI-TOF MS identification of commercial truffles Open
View article: Metaproteomics of the human gut microbiota: Challenges and contributions to other OMICS
Metaproteomics of the human gut microbiota: Challenges and contributions to other OMICS Open
View article: Lactonase Specificity Is Key to Quorum Quenching in <i>Pseudomonas aeruginosa</i>
Lactonase Specificity Is Key to Quorum Quenching in <i>Pseudomonas aeruginosa</i> Open
View article: Complexin in ivermectin resistance in body lice
Complexin in ivermectin resistance in body lice Open
Ivermectin has emerged as very promising pediculicide, particularly in cases of resistance to commonly used pediculicides. Recently, however, the first field-evolved ivermectin-resistance in lice was reported. To gain insight into the mech…
View article: Experimental Analysis of Mimivirus Translation Initiation Factor 4a Reveals Its Importance in Viral Protein Translation during Infection of Acanthamoeba polyphaga
Experimental Analysis of Mimivirus Translation Initiation Factor 4a Reveals Its Importance in Viral Protein Translation during Infection of Acanthamoeba polyphaga Open
The Acanthamoeba polyphaga mimivirus is the first giant virus ever described, with a 1.2-Mb genome which encodes 979 proteins, including central components of the translation apparatus. One of these proteins, R458, was predicted to initiat…
View article: Faustovirus-Like Asfarvirus in Hematophagous Biting Midges and Their Vertebrate Hosts
Faustovirus-Like Asfarvirus in Hematophagous Biting Midges and Their Vertebrate Hosts Open
Faustovirus, a new Asfarviridae-related giant virus, was recently isolated in Vermamoeba vermiformis, a protist found in sewage water in various geographical locations and occasionally reported in human eye infection cases. As part of a gl…