Phillip Chlap
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View article: Implementation of an automated contour quality assurance tool within the TROG 18.01 NINJA trial
Implementation of an automated contour quality assurance tool within the TROG 18.01 NINJA trial Open
These findings support the feasibility of automated contour QA in multicentre trials and offer guidance for future implementation at scale.
View article: Dosimetric Clues to Addressing Urinary Toxicity Following Stereotactic Prostate Radiation Therapy
Dosimetric Clues to Addressing Urinary Toxicity Following Stereotactic Prostate Radiation Therapy Open
Prostate SBRT delivered as a virtual high-dose-rate boost is well tolerated overall. However, delayed GU toxicity is experienced by a significant minority of patients. Additional bladder constraints including D10 cc < 17 Gy and D15 cc < 15…
View article: Mid-treatment changes in intra-tumoural metabolic heterogeneity correlate to outcomes in oropharyngeal squamous cell carcinoma patients
Mid-treatment changes in intra-tumoural metabolic heterogeneity correlate to outcomes in oropharyngeal squamous cell carcinoma patients Open
Background This study evaluated mid-treatment changes in intra-tumoural metabolic heterogeneity and quantitative FDG-PET/CT imaging parameters and correlated the changes with treatment outcomes in oropharyngeal squamous cell cancer (OPSCC)…
View article: PyDicer: An open-source python library for conversion and analysis of radiotherapy DICOM data
PyDicer: An open-source python library for conversion and analysis of radiotherapy DICOM data Open
The organisation, conversion, cleaning and processing of DICOM data is an ongoing challenge across medical image analysis research projects. PyDicer (PYthon Dicom Image ConvertER) was created as a generalisable tool for use across a variet…
View article: Cardiac Substructure Dose and Survival in Stereotactic Radiotherapy for Lung Cancer: Results of the Multi-Centre SSBROC Trial
Cardiac Substructure Dose and Survival in Stereotactic Radiotherapy for Lung Cancer: Results of the Multi-Centre SSBROC Trial Open
Patients treated with lung SABR may receive high doses to cardiac substructures. Dichotomising the patients according to median mean heart dose showed a clear difference in survival. On multivariable analyses gender and dose to ascending a…
View article: Uncertainty estimation using a 3D probabilistic U-Net for segmentation with small radiotherapy clinical trial datasets
Uncertainty estimation using a 3D probabilistic U-Net for segmentation with small radiotherapy clinical trial datasets Open
We demonstrated that training auto-segmentation models which can estimate aleatoric and epistemic uncertainty using limited datasets is possible. Having the model estimate prediction confidence is important to understand for which unseen c…
View article: Dosimetric Impact of Delineation and Motion Uncertainties on the Heart and Substructures in Lung Cancer Radiotherapy
Dosimetric Impact of Delineation and Motion Uncertainties on the Heart and Substructures in Lung Cancer Radiotherapy Open
Radiotherapy dose uncertainties from delineation variations and respiratory-related heart motion were quantified using a cardiac substructure automatic segmentation tool. This predicts the 'dose range' where doses to structures are most li…
View article: Evaluating the relationship between contouring variability and modelled treatment outcome for prostate bed radiotherapy
Evaluating the relationship between contouring variability and modelled treatment outcome for prostate bed radiotherapy Open
Objectives. Contouring similarity metrics are often used in studies of inter-observer variation and automatic segmentation but do not provide an assessment of clinical impact. This study focused on post-prostatectomy radiotherapy and aimed…
View article: LCTSC PyDicer Test Data
LCTSC PyDicer Test Data Open
Subset of TCIA LCTSC data which has been converted using PyDicer for use in testing and examples. Warning: This data has been manipulated (downsampled) to reduce size to make it more appropriate for testing. Citations & Data Usage Policy U…
View article: LCTSC PyDicer Test Data
LCTSC PyDicer Test Data Open
Subset of TCIA LCTSC data which has been converted using PyDicer for use in testing and examples. Warning: This data has been manipulated (downsampled) to reduce size to make it more appropriate for testing. Citations & Data Usage Policy U…
View article: LCTSC PyDicer Test Data
LCTSC PyDicer Test Data Open
Subset of TCIA LCTSC data which has been converted using PyDicer for use in testing and examples. Warning: This data has been manipulated (downsampled) to reduce size to make it more appropriate for testing. Citations & Data Usage Policy U…
View article: LCTSC PyDicer Test Data
LCTSC PyDicer Test Data Open
Subset of TCIA LCTSC data which has been converted using PyDicer for use in testing and examples. Warning: This data has been manipulated (downsampled) to reduce size to make it more appropriate for testing. Citations & Data Usage Policy U…
View article: HNSCC PyDicer Test Data
HNSCC PyDicer Test Data Open
TCIA HNSCC data which has been converted using PyDicer for use in testing. Citations & Data Usage Policy Users of this data must abide by the TCIA Data Usage Policy and the Creative Commons Attribution 3.0 Unported License under which it h…
View article: HNSCC PyDicer Test Data
HNSCC PyDicer Test Data Open
TCIA HNSCC data which has been converted using PyDicer for use in testing. Citations & Data Usage Policy Users of this data must abide by the TCIA Data Usage Policy and the Creative Commons Attribution 3.0 Unported License under which it h…
View article: Assessment of intrafraction motion and its dosimetric impact on prostate radiotherapy using an in-house developed position monitoring system
Assessment of intrafraction motion and its dosimetric impact on prostate radiotherapy using an in-house developed position monitoring system Open
Purpose To implement an in-house developed position monitoring software, SeedTracker, for conventional fractionation prostate radiotherapy, and study the effect on dosimetric impact and intrafraction motion. Methods Thirty definitive prost…
View article: PlatiPy: Processing Library and Analysis Toolkit forMedical Imaging in Python
PlatiPy: Processing Library and Analysis Toolkit forMedical Imaging in Python Open
PlatiPy offers a comprehensive suite of tools and utilities for conducting medical image analysis research utilising Python.These tools include functions for converting data between the clinical standard DICOM format and the research-frien…
View article: Realistic CT data augmentation for accurate deep‐learning based segmentation of head and neck tumors in kV images acquired during radiation therapy
Realistic CT data augmentation for accurate deep‐learning based segmentation of head and neck tumors in kV images acquired during radiation therapy Open
Background Using radiation therapy (RT) to treat head and neck (H&N) cancers requires precise targeting of the tumor to avoid damaging the surrounding healthy organs. Immobilisation masks and planning target volume margins are used to atte…
View article: Open-source, fully-automated hybrid cardiac substructure segmentation: development and optimisation
Open-source, fully-automated hybrid cardiac substructure segmentation: development and optimisation Open
Radiotherapy for thoracic and breast tumours is associated with a range of cardiotoxicities. Emerging evidence suggests cardiac substructure doses may be more predictive of specific outcomes, however, quantitative data necessary to develop…
View article: Impact of tumour region of interest delineation method for mid-treatment FDG-PET response prediction in head and neck squamous cell carcinoma undergoing radiotherapy
Impact of tumour region of interest delineation method for mid-treatment FDG-PET response prediction in head and neck squamous cell carcinoma undergoing radiotherapy Open
Our findings suggest that it is preferable to use gradient based method to assess volumetric tumour response during radiotherapy and offers advantage in predicting treatment outcomes compared with threshold-based methods. This finding requ…
View article: AusCAT Simulation Imaging Data
AusCAT Simulation Imaging Data Open
This data is part of the NCLC Radiomics dataset provided by The Cancer Imaging Archive (TCIA) and is released under the Creative Commons Attribution 3.0 Unported License. CAUTION: This data is provided for experimental purposes only. Data …
View article: AusCAT Simulation Imaging Data
AusCAT Simulation Imaging Data Open
This data is part of the NCLC Radiomics dataset provided by The Cancer Imaging Archive (TCIA) and is released under the Creative Commons Attribution 3.0 Unported License. CAUTION: This data is provided for experimental purposes only. Data …
View article: MRI Distortion QA Tool Phantom Test Dataset
MRI Distortion QA Tool Phantom Test Dataset Open
This data consists of CT and MRI Phantom images captured for the purpose of developing and testing an MRI Distortion QA tool and is released under the Creative Commons Attribution 3.0 Unported License.
View article: Standardising Breast Radiotherapy Structure Naming Conventions: A Machine Learning Approach
Standardising Breast Radiotherapy Structure Naming Conventions: A Machine Learning Approach Open
In progressing the use of big data in health systems, standardised nomenclature is required to enable data pooling and analyses. In many radiotherapy planning systems and their data archives, target volumes (TV) and organ-at-risk (OAR) str…
View article: MRI Distortion QA Tool Phantom Test Dataset
MRI Distortion QA Tool Phantom Test Dataset Open
This data consists of CT and MRI Phantom images captured for the purpose of developing and testing an MRI Distortion QA tool and is released under the Creative Commons Attribution 3.0 Unported License.
View article: Contour Comparison Example Data
Contour Comparison Example Data Open
Some test data extracted from the TCIA used for some examples to demonstrate how to compute contour comparison metrics. WARNING: This is sample/dummy data, only intended for demonstration purposes. This data is part of the LCTSC dataset pr…
View article: Contour Comparison Example Data
Contour Comparison Example Data Open
Some test data extracted from the TCIA used for some examples to demonstrate how to compute contour comparison metrics. WARNING: This is sample/dummy data, only intended for demonstration purposes. This data is part of the LCTSC dataset pr…