P. Lee Ferguson
YOU?
Author Swipe
View article: The effect of mechanical canopy reduction on big sagebrush plant communities
The effect of mechanical canopy reduction on big sagebrush plant communities Open
A major conservation challenge in the western United States is implementing management treatments that reduce fire risk, control for invasive species, and maintain herbaceous understories in big sagebrush ecosystems. Studies have found tha…
View article: Environmental exposure assessment in the international prospective study of Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) research consortium: Design and protocol development
Environmental exposure assessment in the international prospective study of Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) research consortium: Design and protocol development Open
CURE will provide critical insights into CKDu risk factors, supporting future research and prevention strategies. A comprehensive exposure assessment will enhance understanding of environmental contributors, guiding interventions at indivi…
View article: Assessment of developmental neurotoxicology-associated alterations in neuronal architecture and function using Caenorhabditis elegans
Assessment of developmental neurotoxicology-associated alterations in neuronal architecture and function using Caenorhabditis elegans Open
Few of the many chemicals that regulatory agencies are charged with assessing for risk have been carefully tested for developmental neurotoxicity (DNT). To speed up assessment, and to reduce the use of vertebrate animals, great effort is b…
View article: Wristband Personal Passive Samplers and Suspect Screening Methods Highlight Gender Disparities in Chemical Exposures
Wristband Personal Passive Samplers and Suspect Screening Methods Highlight Gender Disparities in Chemical Exposures Open
Wristband personal samplers enable human exposure assessments for a diverse range of chemical contaminants and exposure settings with a previously unattainable scale and cost-effectiveness. Paired with nontargeted analyses, wristbands can …
View article: Advancing Understanding of Chemical Exposures and Maternal-child Health Through the U.S. Environmental Influences on Child Health Outcomes (ECHO) Program: A Scoping Review
Advancing Understanding of Chemical Exposures and Maternal-child Health Through the U.S. Environmental Influences on Child Health Outcomes (ECHO) Program: A Scoping Review Open
Purpose of Review Environmental chemical exposures may disrupt child development, with long-lasting health impacts. To date, U.S. studies of early environmental exposures have been limited in size and diversity, hindering power and general…
View article: Lithium-ion battery components are at the nexus of sustainable energy and environmental release of per- and polyfluoroalkyl substances
Lithium-ion battery components are at the nexus of sustainable energy and environmental release of per- and polyfluoroalkyl substances Open
Lithium-ion batteries (LiBs) are used globally as a key component of clean and sustainable energy infrastructure, and emerging LiB technologies have incorporated a class of per- and polyfluoroalkyl substances (PFAS) known as bis-perfluoroa…
View article: Lack of detectable sex differences in the mitochondrial function of Caenorhabditis elegans
Lack of detectable sex differences in the mitochondrial function of Caenorhabditis elegans Open
Background Sex differences in mitochondrial function have been reported in multiple tissue and cell types. Additionally, sex-variable responses to stressors including environmental pollutants and drugs that cause mitochondrial toxicity hav…
View article: Rebuttal to Comment on “Glyphosate and Fluoride in High-Hardness Drinking Water Are Positively Associated with Chronic Kidney Disease of Unknown Etiology (CKDu) in Sri Lanka”
Rebuttal to Comment on “Glyphosate and Fluoride in High-Hardness Drinking Water Are Positively Associated with Chronic Kidney Disease of Unknown Etiology (CKDu) in Sri Lanka” Open
ADVERTISEMENT RETURN TO ISSUEPREVCorrespondenceNEXTORIGINAL ARTICLEThis notice is a correctionRebuttal to Comment on "Glyphosate and Fluoride in High-Hardness Drinking Water Are Positively Associated with Chronic Kidney Disease of Unknown …
View article: Assessment of Fluoropolymer Production and Use With Analysis of Alternative Replacement Materials
Assessment of Fluoropolymer Production and Use With Analysis of Alternative Replacement Materials Open
This report focuses on fluoropolymers, which are a subgroup of the much larger class of fluorinated chemicals known as per- and polyfluoroalkyl substances (PFAS). Clearly distinguishing fluoropolymers is important to understanding their di…
View article: The dirty side of clean energy: Lithium ion batteries as a source of PFAS in the environment
The dirty side of clean energy: Lithium ion batteries as a source of PFAS in the environment Open
Lithium ion batteries (LiBs) are used globally as a key component of clean and sustainable energy iinfrastructure1,2. Emerging LiB technologies have incorporated a novel class of per- and polyfluoroalkyl substances (PFAS, i.e., "forever ch…
View article: How Many Chemicals in Commerce Have Been Analyzed in Environmental Media? A 50 Year Bibliometric Analysis
How Many Chemicals in Commerce Have Been Analyzed in Environmental Media? A 50 Year Bibliometric Analysis Open
Over the past 50 years, there has been a tremendous expansion in the measurement of chemical contaminants in environmental media. But how many chemicals have actually been determined, and do they represent a significant fraction of substan…
View article: Matrix Matters: novel insights for the extraction, preparation, and quantitation of microplastics in a freshwater mesocosm study
Matrix Matters: novel insights for the extraction, preparation, and quantitation of microplastics in a freshwater mesocosm study Open
The extraction and characterization of secondary microplastics, those formed through subjection to the environment, must continuously improve in accuracy and applicability in order to generate robust microplastics exposure and risk assessm…
View article: Quantitation of Total PFAS Including Trifluoroacetic Acid with Fluorine Nuclear Magnetic Resonance Spectroscopy
Quantitation of Total PFAS Including Trifluoroacetic Acid with Fluorine Nuclear Magnetic Resonance Spectroscopy Open
Fluorine nuclear magnetic resonance (19F-NMR) spectroscopy has been shown to be a powerful tool capable of quantifying the total per- and polyfluoroalkyl substances (PFAS) in a complex sample. The technique relies on the characteristic ter…
View article: Novel per- and polyfluoroalkyl substances in an active-use C6-based aqueous film forming foam
Novel per- and polyfluoroalkyl substances in an active-use C6-based aqueous film forming foam Open
Studies have identified hundreds of per- and polyfluoroalkyl substances (PFAS) in aqueous film forming foam (AFFF) using high resolution mass spectrometry (HRMS), and there is increasing reliance on HRMS with suspect screening in areas suc…
View article: Per- and polyfluoroalkyl substances (PFAS) in river discharge: Modeling loads upstream and downstream of a PFAS manufacturing plant in the Cape Fear watershed, North Carolina
Per- and polyfluoroalkyl substances (PFAS) in river discharge: Modeling loads upstream and downstream of a PFAS manufacturing plant in the Cape Fear watershed, North Carolina Open
The Cape Fear River is an important source of drinking water in North Carolina, and many drinking water intakes in the watershed are affected by per- and polyfluoroalkyl substances (PFAS). We quantified PFAS concentrations and loads in riv…
View article: Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and Their <i>In Vitro</i> Adipogenic Activity
Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and Their <i>In Vitro</i> Adipogenic Activity Open
Anti-fog sprays and solutions are used on eyeglasses to minimize the condensation of water vapor, particularly while wearing a mask. Given their water-repellent properties, we sought to characterize per- and polyfluorinated alkyl substance…
View article: Data and scripts from: A structure database and in silico spectral library for comprehensive suspect screening of per- and polyfluoroalkyl substances (PFASs) in environmental media by high-resolution mass spectrometry
Data and scripts from: A structure database and in silico spectral library for comprehensive suspect screening of per- and polyfluoroalkyl substances (PFASs) in environmental media by high-resolution mass spectrometry Open
Per and polyfluoroalkyl substances (PFASs) are an important class of organic pollutants. Many diverse PFASs are used in commerce and most are not amenable to conventional targeted chemical analysis due to lack of reference standards. There…
View article: Structure Database and <i>In Silico</i> Spectral Library for Comprehensive Suspect Screening of Per- and Polyfluoroalkyl Substances (PFASs) in Environmental Media by High-resolution Mass Spectrometry
Structure Database and <i>In Silico</i> Spectral Library for Comprehensive Suspect Screening of Per- and Polyfluoroalkyl Substances (PFASs) in Environmental Media by High-resolution Mass Spectrometry Open
Per and polyfluoroalkyl substances (PFASs) are an important class of organic pollutants. Many diverse PFASs are used in commerce and most are not amenable to conventional targeted chemical analysis due to lack of reference standards. There…
View article: Assessment of emerging polar organic pollutants linked to contaminant pathways within an urban estuary using non-targeted analysis
Assessment of emerging polar organic pollutants linked to contaminant pathways within an urban estuary using non-targeted analysis Open
Non-targeted analysis of polar organic pollutants using high resolution/accurate mass (HR/AM) mass spectrometry has been conducted in waters of San Francisco (SF) Bay to assess occurrence of emerging contaminants and inform future monitori…
View article: Data and scripts from: A structure database and in silico spectral library for comprehensive suspect screening of per- and polyfluoroalkyl substances (PFASs) in environmental media by high-resolution mass spectrometry
Data and scripts from: A structure database and in silico spectral library for comprehensive suspect screening of per- and polyfluoroalkyl substances (PFASs) in environmental media by high-resolution mass spectrometry Open
Per and polyfluoroalkyl substances (PFASs) are an important class of organic pollutants. Many diverse PFASs are used in commerce and most are not amenable to conventional targeted chemical analysis due to lack of reference standards. There…
View article: Kidney developmental effects of metal-herbicide mixtures: Implications for chronic kidney disease of unknown etiology
Kidney developmental effects of metal-herbicide mixtures: Implications for chronic kidney disease of unknown etiology Open
Chronic kidney disease of unknown etiology (CKDu) is an emerging global concern affecting several agricultural communities in the Americas and South Asia. Environmental contaminants such as heavy metals (e.g., Cd, As, Pb, and V) and organi…
View article: Chronic microfiber exposure in adult Japanese medaka (Oryzias latipes)
Chronic microfiber exposure in adult Japanese medaka (Oryzias latipes) Open
Microplastic fibers (MFs) pollute aquatic habitats globally via sewage release, stormwater runoff, or atmospheric deposition. Of the synthetic MFs, polyester (PES) and polypropylene (PP) are the most common. Field studies show that fish in…
View article: <i>In Vitro</i> Metabolism of Isopropylated and <i>tert</i>-Butylated Triarylphosphate Esters Using Human Liver Subcellular Fractions
<i>In Vitro</i> Metabolism of Isopropylated and <i>tert</i>-Butylated Triarylphosphate Esters Using Human Liver Subcellular Fractions Open
Isopropylated and tert-butylated triarylphosphate esters (ITPs and TBPPs) are plasticizers and flame retardants that are ubiquitous in indoor environments; however, no studies to date have characterized their metabolism. Using human liver …
View article: In Vitro Metabolism of Isopropylatedand tert-Butylated Triarylphosphate Esters UsingHuman Liver Subcellular Fractions
In Vitro Metabolism of Isopropylatedand tert-Butylated Triarylphosphate Esters UsingHuman Liver Subcellular Fractions Open
Isopropylated\nand tert-butylated triarylphosphate\nesters (ITPs and TBPPs, respectively) are plasticizers and flame retardants\nthat are ubiquitous in indoor environments; however, no studies to\ndate have characterized their metabolism. …