Peipei Guo
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View article: Toxicity of Tris(2-chloroethyl) Phosphate (TCEP) to Alfalfa’s Root System: An Insight into TCEP’s Damage to Morphology, Respiration, and Antioxidant Systems
Toxicity of Tris(2-chloroethyl) Phosphate (TCEP) to Alfalfa’s Root System: An Insight into TCEP’s Damage to Morphology, Respiration, and Antioxidant Systems Open
Tris(2-chloroethyl) phosphate (TCEP), as an organophosphate contaminant, poses a significant threat to the growth and development of plants, especially roots. This study aimed to clarify the mechanisms of TCEP’s toxicity and damage to root…
View article: A hematological and inflammatory marker-based model for prostate carcinoma diagnosis
A hematological and inflammatory marker-based model for prostate carcinoma diagnosis Open
Prostate carcinoma (PC) is the most frequently diagnosed malignancy and the third leading cause of cancer-related death among men in the United States, with over 160,000 new cases reported annually. While prostate-specific antigen (PSA) sc…
View article: Rosehip (Rosa rugosa Thunb.) ethanol extract ameliorates liver fibrosis through upregulation of the PPAR signaling pathway
Rosehip (Rosa rugosa Thunb.) ethanol extract ameliorates liver fibrosis through upregulation of the PPAR signaling pathway Open
The objective of this study was to examine the effect of rosehip (Rosa rugosa Thunb.) ethanol extract (RRE) on liver fibrosis in mice and the underlying molecular mechanisms. RRE has no acute oral toxicity, and the MTD in mice is 46.14 g/k…
View article: A Better Fruit Quality of Grafted Blueberry Than Own-Rooted Blueberry Is Linked to Its Anatomy
A Better Fruit Quality of Grafted Blueberry Than Own-Rooted Blueberry Is Linked to Its Anatomy Open
To further clarify the impact of different rootstocks in grafted blueberry, fruit quality, mineral contents, and leaf gas exchange were investigated in ‘O’Neal’ blueberry (Vaccinium corymbosum) grafted onto ‘Anna’ (V. corymbosum) (AO), ‘Sh…
View article: Long-lasting humoral and cellular memory immunity to vaccinia virus Tiantan provides pre-existing immunity against mpox virus in Chinese population
Long-lasting humoral and cellular memory immunity to vaccinia virus Tiantan provides pre-existing immunity against mpox virus in Chinese population Open
Investigating immune memory to vaccinia virus and pre-existing immunity to mpox virus (MPXV) among the population is crucial for the global response to this ongoing mpox epidemic. Blood was sampled from vaccinees inoculated with vaccinia v…
View article: Genome-wide analysis of serine carboxypeptidase-like protein (SCPL) family and functional validation of Gh_SCPL42 unchromosome conferring cotton Verticillium der Verticillium wilt stress in Gossypium hirsutum
Genome-wide analysis of serine carboxypeptidase-like protein (SCPL) family and functional validation of Gh_SCPL42 unchromosome conferring cotton Verticillium der Verticillium wilt stress in Gossypium hirsutum Open
Background Serine carboxypeptidase-like protein (SCPL) plays an important role in response to stress in plant. However, our knowledge of the function of the SCPL gene family is limited. Results In this study, a comprehensive and systematic…
View article: Association between sperm MT-COX1 gene variations and semen quality in the Chinese Han population
Association between sperm MT-COX1 gene variations and semen quality in the Chinese Han population Open
Backgroud : Male sperm quality has declined as a whole in the last 30 years and our previous study found that there are many specific variations in male sperm mitochondria, including MT-COX1. In this study we attempted to explore the corre…
View article: Tumour endothelial cells for translational research and therapeutics
Tumour endothelial cells for translational research and therapeutics Open
Tumour vascularization plays an important role in tumour development and progression. Tumour endothelial cells (TECs) form the inner lining of tumour blood vessels. TECs are mainly derived from endothelial progenitor cells (EPCs); however,…
View article: Additional file 2 of Genome-wide analysis of serine carboxypeptidase-like protein (SCPL) family and functional validation of Gh_SCPL42 unchromosome conferring cotton Verticillium der Verticillium wilt stress in Gossypium hirsutum
Additional file 2 of Genome-wide analysis of serine carboxypeptidase-like protein (SCPL) family and functional validation of Gh_SCPL42 unchromosome conferring cotton Verticillium der Verticillium wilt stress in Gossypium hirsutum Open
Additional file 2.
View article: Role of endothelial cells in tumor microenvironment
Role of endothelial cells in tumor microenvironment Open
To the Editor: Endothelial cells line the vascular system and play essential roles in regulating tumor initiation, progression, and metastasis. The application of single-cell RNA sequencing has identified distinct lineages of endothelial c…
View article: Vascular Notch Signaling in Stress Hematopoiesis
Vascular Notch Signaling in Stress Hematopoiesis Open
Canonical Notch signaling is one of the most conserved signaling cascades. It regulates cell proliferation, cell differentiation, and cell fate maintenance in a variety of biological systems during development and cancer (Fortini, 2009 ; K…
View article: Impaired Myeloid-derived Suppressor Cells Are Associated With Recurrent Implantation Failure: A Case-Control Study
Impaired Myeloid-derived Suppressor Cells Are Associated With Recurrent Implantation Failure: A Case-Control Study Open
Background: Studies have reported that myeloid-derived suppressor cells (MDSCs) contribute to maintain pregnancy. The aim of this case-control study was to test whether there is a dysregulation of peripheral MDSCs in recurrent implantation…
View article: Burned Ear Reconstruction Using a Superficial Temporal Fascia Flap
Burned Ear Reconstruction Using a Superficial Temporal Fascia Flap Open
Objectives: Ear deformity caused by burns is one of the most difficult types of deformity to treat with plastic surgery, and the reconstruction of burned ears undoubtedly remains a substantial challenge. This study aims to report the thera…
View article: Symptoms at disease onset predict prognosis in COVID-19 disease
Symptoms at disease onset predict prognosis in COVID-19 disease Open
Background: The main clinical manifestations of coronavirus disease 2019 (COVID-19) onset are respiratory symptoms, including cough, sputum and dyspnea. However, a significant proportion of patients initially manifested extra-respiratory s…
View article: Effects of exogenous glutathione on antioxidant system of cucumber seedlings under cadmium stress
Effects of exogenous glutathione on antioxidant system of cucumber seedlings under cadmium stress Open
With the development of social economy, environmental protection has become a hot topic. Excessive emissions of agricultural chemicals increase the accumulation of the heavy metal cadmium (Cd) in soil. When plants are stressed by high conc…
View article: Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration Open
BMP4 produced by endothelial cells promotes thymic regeneration after acute damage by activating FOXN1 and its downstream targets.
View article: Generation of BMEC Lines and in vitro BMEC-HSPC Co-culture Assays
Generation of BMEC Lines and in vitro BMEC-HSPC Co-culture Assays Open
Endothelial cells (ECs) sustain the self-renewal and regeneration of adult hematopoietic stem and progenitor cells (HSPCs) via deployment of EC-derived paracrine factors, termed as angiocrine factors. Generation of durable ex vivo vascular…
View article: Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression
Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression Open
Angiocrine factors, such as Notch ligands, supplied by the specialized endothelial cells (ECs) within the bone marrow and splenic vascular niche play an essential role in modulating the physiology of adult hematopoietic stem and progenitor…
View article: Activated ovarian endothelial cells promote early follicular development and survival
Activated ovarian endothelial cells promote early follicular development and survival Open
In vitro development of early follicles necessitates a complex interplay of growth factors and signals required for development. Endothelial cells (ECs) may elaborate essential "angiocrine factors" involved in organ regeneration. We demons…
View article: Supplementary Material for: Polymorphisms in Sex Hormone Metabolism Genes and Risk of Preeclampsia in Taiyuan, China
Supplementary Material for: Polymorphisms in Sex Hormone Metabolism Genes and Risk of Preeclampsia in Taiyuan, China Open
Objective: Aberrant synthesis and metabolism of sex hormone are likely to be associated with alterations in vascular function in preeclampsia (PE). The study aims to investigate whether single nucleotide polymorphisms (SNPs) in sex hormone…