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View article: Effectiveness of a bedaquiline, linezolid, clofazimine ‘core’ for multidrug-resistant TB
Effectiveness of a bedaquiline, linezolid, clofazimine ‘core’ for multidrug-resistant TB Open
BACKGROUNDTreatment outcomes may be compromised among individuals with multidrug/rifampicin-resistant TB (MDR/RR-TB) with fluoroquinolone (FQ) resistance. Among people in whom an FQ was unlikely to be effective, we compared the effectivene…
View article: A 10-year review of isoniazid-resistant TB management in Uzbekistan 2009-2020
A 10-year review of isoniazid-resistant TB management in Uzbekistan 2009-2020 Open
BACKGROUNDIsoniazid (INH, H) resistance is the most common drug-resistant TB pattern, with treatment success rates lower than those in drug-susceptible TB. The WHO recommends a 6-month regimen of rifampicin (RIF, R), ethambutol (EMB, E), p…
View article: Effectiveness of a bedaquiline, linezolid, clofazimine “core” for multidrug-resistant tuberculosis
Effectiveness of a bedaquiline, linezolid, clofazimine “core” for multidrug-resistant tuberculosis Open
Rationale Treatment outcomes may be compromised among patients with multidrug- or rifampicin-resistant tuberculosis with additional fluoroquinolone resistance. Evidence is needed to inform optimal treatment for these patients. Objectives W…
View article: Epidemiological characteristics and real‐world treatment outcomes of hepatitis C among HIV/HCV co‐infected patients in Myanmar: A prospective cohort study
Epidemiological characteristics and real‐world treatment outcomes of hepatitis C among HIV/HCV co‐infected patients in Myanmar: A prospective cohort study Open
Background and Aims In Myanmar, public sector treatment programs for hepatitis C virus (HCV) infection were nonexistent until June 2017. WHO highlights the importance of simplification of HCV service delivery through task‐shifting among he…
View article: Advanced HIV disease and associated attrition after re-engagement in HIV care in Myanmar from 2003 to 2019: a retrospective cohort study
Advanced HIV disease and associated attrition after re-engagement in HIV care in Myanmar from 2003 to 2019: a retrospective cohort study Open
Background The burden of advanced HIV disease (AHD) and predictors of outcomes among people living with HIV (PLHIV) re-engaging in care are not well known. Methods We conducted a retrospective cohort study of PLHIV who re-engaged in care a…
View article: Safety of Treatment Regimens Containing Bedaquiline and Delamanid in the endTB Cohort
Safety of Treatment Regimens Containing Bedaquiline and Delamanid in the endTB Cohort Open
Background Safety of treatment for multidrug-resistant tuberculosis (MDR/RR-TB) can be an obstacle to treatment completion. Evaluate safety of longer MDR/RR-TB regimens containing bedaquiline and/or delamanid. Methods Multicentre (16 count…