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View article: Treatment of <i>Acanthamoeba</i> keratitis with high dose PHMB (0.08%) monotherapy in clinical practice: A case series
Treatment of <i>Acanthamoeba</i> keratitis with high dose PHMB (0.08%) monotherapy in clinical practice: A case series Open
Objectives Acanthamoeba keratitis (AK) is a rare sight-threatening infectious disease with no approved pharmacological treatments . Topical polihexanide 0.8 mg/ml (PHMB 0.08%) completed a pivotal clinical trial showing a medical cure rate …
View article: The Orphan Drug for Acanthamoeba Keratitis (ODAK) Trial
The Orphan Drug for Acanthamoeba Keratitis (ODAK) Trial Open
Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
View article: Sterile Corneal Infiltrates following Cataract Surgery: Case Series
Sterile Corneal Infiltrates following Cataract Surgery: Case Series Open
We report a case series of 26 eyes of 26 patients undergoing planned cataract surgery from December 2021 to March 2022, who were diagnosed as having whitish round infiltrates in the surgical corneal incisions. The infiltrates were detected…
View article: Hemi-Ultrathin Descemet Stripping Automated Endothelial Keratoplasty (Hemi-UT-DSAEK) Using Pediatric Donor Corneas: A Case Series
Hemi-Ultrathin Descemet Stripping Automated Endothelial Keratoplasty (Hemi-UT-DSAEK) Using Pediatric Donor Corneas: A Case Series Open
Objective: We sought to evaluate the clinical outcomes of hemi-UT-DSAEK grafts from the pediatric donor corneas of patients affected by Fuchs Endothelial Corneal Dystrophy (FECD). Methods: A prospective, interventional case series was cond…
View article: Recurrent keratoconus: an analysis of breaks in Bowman’s layer in corneal grafts
Recurrent keratoconus: an analysis of breaks in Bowman’s layer in corneal grafts Open
Objective To study in a masked fashion whether an objective histological feature associated with keratoconus (KCN) occurs in donor corneas in eyes originally receiving a corneal graft for KCN. Methods Two ocular pathologists performed a re…
View article: Supplementary Material for: Sterile corneal infiltrates following cataract surgery: case series.
Supplementary Material for: Sterile corneal infiltrates following cataract surgery: case series. Open
We report a case series of twenty-six eyes of 26 patients undergoing planned cataract surgery from December 2021 to March 2022, who were diagnosed as having whitish round infiltrates in the surgical corneal incisions. The infiltrates were …
View article: Corneal transplantation during the COVID-19 pandemic: An operational guide
Corneal transplantation during the COVID-19 pandemic: An operational guide Open
Purpose: To provide an operational guide for corneal transplantation during the COVID-19 pandemic aimed to maintain surgery and avoid spreading of SARS-CoV-2. Methods: Prospective observational case series study in patients requiring corne…
View article: Biobanking corneal tissues for emergency procedures during COVID-19 era
Biobanking corneal tissues for emergency procedures during COVID-19 era Open
Dear Editor, COVID-19 pandemic has significantly affected the ophthalmic practice and the eye banking field.[12] Hence, new guidelines are being developed to safeguard corneal transplantation. Recently, in a retrospective study, we reporte…
View article: Shotgun sequencing to determine corneal infection
Shotgun sequencing to determine corneal infection Open
Shotgun sequencing is a hypothesis-free approach that identifies full taxonomic and functional profile of an organism. This technology is advantageous as it requires smaller sample size compared to conventional diagnostic methods.
View article: Reply
Reply Open
Reply to letter about previous article: Factors Associated With Early Graft Detachment in Primary Descemet Membrane Endothelial Keratoplasty, by eon P, Parekh M, Nahum Y, Mimouni M, Giannaccare G, Sapigni L, Ruzza A, Busin M. published in …
View article: Outcomes of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) performed in eyes with failure of primary Descemet membrane endothelial keratoplasty (DMEK)
Outcomes of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) performed in eyes with failure of primary Descemet membrane endothelial keratoplasty (DMEK) Open
Aim To evaluate the outcomes of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) performed in eyes after failure of primary Descemet membrane endothelial keratoplasty (DMEK). Methods This was a retrospective, non-…
View article: Combined therapy (intravitreal bevacizumab plus verteporfin photodynamic therapy) versus intravitreal bevacizumab monotherapy for choroidal neovascularization due to age-related macular degeneration: a 1-year follow-up study
Combined therapy (intravitreal bevacizumab plus verteporfin photodynamic therapy) versus intravitreal bevacizumab monotherapy for choroidal neovascularization due to age-related macular degeneration: a 1-year follow-up study Open
PurposeTo assess the efficacy and safety of combined intravitreal bevacizumab and low-fluency-rate photodynamic therapy (PDT) in the treatment of choroidal neovascularization (CNV) associated with age-related macular degeneration (AMD) and…
View article: An evaluation of intraoperative and postoperative outcomes of torsional mode versus longitudinal ultrasound mode phacoemulsification: a Meta-analysis
An evaluation of intraoperative and postoperative outcomes of torsional mode versus longitudinal ultrasound mode phacoemulsification: a Meta-analysis Open
The Meta-analysis shows the superiority of the torsional mode for intraoperative parameters (UST, CDE) and postoperative ECL outcomes.
View article: Outcomes of Air Injection Within 2 mm Inside a Deep Trephination for Deep Anterior Lamellar Keratoplasty in Eyes With Keratoconus
Outcomes of Air Injection Within 2 mm Inside a Deep Trephination for Deep Anterior Lamellar Keratoplasty in Eyes With Keratoconus Open
Setting an adjustable trephine to a depth within 100 μm from the endothelial surface eliminates the need for reaching the central cornea for successful pneumatic dissection and substantially flattens the learning curve of DALK, while achie…
View article: Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman
Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman Open
Purpose . To report a case of unilateral optic neuritis following Measles-Mumps-Rubella (MMR) vaccination. Methods . A 30-year-old female developed unilateral optic neuritis five days after a Measles-Mumps-Rubella (MMR) booster vaccination…