Pier Francesco Alesina
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View article: Editorial: Primary and secondary hyperparathyroidism: from etiology to treatment
Editorial: Primary and secondary hyperparathyroidism: from etiology to treatment Open
View article: Parathyroidectomy and the use of ioPTH. A survey of the United Italian Society of Endocrine Surgery (SIUEC)
Parathyroidectomy and the use of ioPTH. A survey of the United Italian Society of Endocrine Surgery (SIUEC) Open
Primary hyperparathyroidism (PHPT) is a frequent endocrine disorder, with surgery as the only curative option. Despite evolving guidelines, real-life management remains variable across centers. A national survey was conducted among members…
View article: Partial Adrenalectomy Is Not Associated with Increased Risk of Hemodynamic Instability in Patients with Pheochromocytoma
Partial Adrenalectomy Is Not Associated with Increased Risk of Hemodynamic Instability in Patients with Pheochromocytoma Open
Background Partial adrenalectomy (PA) is a viable treatment option for patients with adrenal tumours, particularly with pheochromocytomas. PA requires precise intraoperative visualization of the tumour increasing the risk of intraoperative…
View article: Thoracoscopic parathyroidectomy: a 22-year experience
Thoracoscopic parathyroidectomy: a 22-year experience Open
Thoracoscopic parathyroidectomy (TP) is a preferred approach to the treatment of hyperparathyroidism (HPT), caused by hyperfunctioning parathyroid glands located in mediastinum, though the data on its feasibility and safety are scarce, due…
View article: Partial adrenalectomy by the posterior retroperitoneoscopic approach: A single institution series of 766 consecutive procedures
Partial adrenalectomy by the posterior retroperitoneoscopic approach: A single institution series of 766 consecutive procedures Open
Background Partial adrenalectomy (PA), as an alternative to total adrenalectomy in selected cases, allows for the preservation of adrenocortical function, especially in hereditary and/or bilateral diseases. In this study, we analyze our ex…
View article: Adrenocortical Carcinoma: The Posterior Minimally Invasive Approach
Adrenocortical Carcinoma: The Posterior Minimally Invasive Approach Open
Adrenocortical carcinoma (ACC) is an aggressive cancer, and comprehensive preoperative assessment, including imaging and staging, is essential to determine the feasibility of a minimally invasive approach. Posterior retroperitoneoscopic ad…
View article: Development of an ontology for laparoscopic transabdominal adrenalectomy via a comprehensive modified Delphi survey and its validation on a multicentric pilot data set for surgical training and future video analysis with machine learning algorithms
Development of an ontology for laparoscopic transabdominal adrenalectomy via a comprehensive modified Delphi survey and its validation on a multicentric pilot data set for surgical training and future video analysis with machine learning algorithms Open
Lay Summary Surgical technique is essential to ensure safe minimally invasive adrenalectomy. Due to the relative rarity of adrenal surgery, it is challenging to ensure adequate exposure in surgical training. Surgical video analysis support…
View article: Long‐term outcome of retroperitoneoscopic partial versus total adrenalectomy in patients with Cushing's syndrome
Long‐term outcome of retroperitoneoscopic partial versus total adrenalectomy in patients with Cushing's syndrome Open
Background We analyze the long‐term outcome of surgery for Cushing's syndrome (CS) and the influence of the extent of surgical resection on the duration of postoperative cortisone substitution. Methods One‐hundred forty‐one patients (129 f…
View article: Primary perioperative haemodynamic effects of ß-receptor blockade in patients with catecholamine-secreting tumours
Primary perioperative haemodynamic effects of ß-receptor blockade in patients with catecholamine-secreting tumours Open
Overall, patients with isolated ß-receptor blockade developed higher blood pressure before operation and intraoperatively. After propensity score matching a difference could no longer be detected. Overall, ß-receptor blockade seems to be m…
View article: Use of fluorescence imaging and indocyanine green during thyroid and parathyroid surgery: Results of an intercontinental, multidisciplinary Delphi survey
Use of fluorescence imaging and indocyanine green during thyroid and parathyroid surgery: Results of an intercontinental, multidisciplinary Delphi survey Open
View article: Abstracts der 40. Arbeitstagung der Chirurgischen Arbeitsgemeinschaft Endokrinologie (CAEK)
Abstracts der 40. Arbeitstagung der Chirurgischen Arbeitsgemeinschaft Endokrinologie (CAEK) Open
View article: Minimally invasive video-assisted parathyroidectomy (MIVAP) versus conventional parathyroidectomy for renal hyperparathyroidism: a retrospective multicenter study
Minimally invasive video-assisted parathyroidectomy (MIVAP) versus conventional parathyroidectomy for renal hyperparathyroidism: a retrospective multicenter study Open
To compare minimally invasive video-assisted parathyroidectomy (MIVAP) versus conventional surgery for renal hyperparathyroidism (rHPT). Between 2006 and 2020, 53 patients underwent MIVAP and 182 underwent conventional parathyroidectomy fo…
View article: Tailored Approach in Adrenal Surgery: Retroperitoneoscopic Partial Adrenalectomy
Tailored Approach in Adrenal Surgery: Retroperitoneoscopic Partial Adrenalectomy Open
The interest on partial adrenalectomy has steadily increased over the past twenty years. Adrenal pathologies are mostly benign, making an organ-preserving procedure attractive for many patients. The introduction of minimally invasive techn…
View article: Fluorescence Image-Guided Surgery for Thyroid Cancer: Utility for Preventing Hypoparathyroidism
Fluorescence Image-Guided Surgery for Thyroid Cancer: Utility for Preventing Hypoparathyroidism Open
Background: Hypoparathyroidism is one of the most frequent complications of thyroid surgery, especially when associated with lymph node dissection in cases of thyroid cancer. Fluorescence-guided surgery is an emerging tool that appears to …
View article: X-chromosome variants are associated with aldosterone producing adenomas
X-chromosome variants are associated with aldosterone producing adenomas Open
Aldosterone-producing adenomas (APAs) are a major cause of primary aldosteronism (PA) and are characterized by constitutively producing aldosterone, which leads to hypertension. Several mutations have been identified in ion channels or ion…
View article: Catecholamine Concentrations during and after Retroperitoneoscopic Adrenalectomies in Surgeon, Anaesthetist and Patients – how is physiological stress different from pathophysiological stress?
Catecholamine Concentrations during and after Retroperitoneoscopic Adrenalectomies in Surgeon, Anaesthetist and Patients – how is physiological stress different from pathophysiological stress? Open
Background: During resections of phaeochromocytoma release of catecholamines can lead to excessive hypertension and arrhythmia. Therefore, these procedures can be stressful to surgeons and anaesthetists. It is completely unknown, how the e…
View article: Differentiating Benign from Malignant Adrenocortical Tumors by a Single Morphological Parameter—a Clinicopathological Study on 837 Adrenocortical Neoplasias
Differentiating Benign from Malignant Adrenocortical Tumors by a Single Morphological Parameter—a Clinicopathological Study on 837 Adrenocortical Neoplasias Open
View article: Intraoperative imaging for remnant viability assessment in bilateral posterior retroperitoneoscopic partial adrenalectomy in an experimental model
Intraoperative imaging for remnant viability assessment in bilateral posterior retroperitoneoscopic partial adrenalectomy in an experimental model Open
Background A surgical approach preserving functional adrenal tissue allows biochemical cure while avoiding the need for lifelong steroid replacement. The aim of this experimental study was to evaluate the impact of intraoperative imaging d…
View article: International multicentre review of perioperative management and outcome for catecholamine-producing tumours
International multicentre review of perioperative management and outcome for catecholamine-producing tumours Open
Background Surgery for catecholamine-producing tumours can be complicated by intraoperative and postoperative haemodynamic instability. Several perioperative management strategies have emerged but none has been evaluated in randomized tria…
View article: Adrenal Tumors: Are Gender Aspects Relevant?
Adrenal Tumors: Are Gender Aspects Relevant? Open
The distribution of malignant tumors is strongly related to gender due to sex-related organ and tissue differentiation. Neoplasias of the adrenal glands are relatively common and typically benign. Mainly based on our recently published con…
View article: Retroperitoneal adrenalectomy—learning curve, practical tips and tricks, what limits its wider uptake
Retroperitoneal adrenalectomy—learning curve, practical tips and tricks, what limits its wider uptake Open
The minimally invasive retroperitoneal approach to the adrenal surgery has been described in the early 90s following the first description of laparoscopic adrenalectomy. Although the advantages of the technique compared to laparoscopic sur…
View article: Reply to Comment to: A simplified surgical technique for recurrent inguinal hernia repair following total extraperitoneal patch plastic. Balta AZ, Senol Z, Sucullo I
Reply to Comment to: A simplified surgical technique for recurrent inguinal hernia repair following total extraperitoneal patch plastic. Balta AZ, Senol Z, Sucullo I Open
View article: Continuous intraoperative neuromonitoring in minimally invasive video assisted thyroid surgery: first experience
Continuous intraoperative neuromonitoring in minimally invasive video assisted thyroid surgery: first experience Open
Background: Visual identification of the recurrent laryngeal nerve (RLN) is mandatory in thyroid surgery independent of the approach. Intermittent intraoperative neuromonitoring (ioNM) is broadly in open and minimally invasive thyroid surg…
View article: Perioperative α-receptor blockade in phaeochromocytoma surgery: an observational case series
Perioperative α-receptor blockade in phaeochromocytoma surgery: an observational case series Open
View article: The Effect of Early Thyroidectomy on the Course of Active Graves’ Orbitopathy (GO): A Retrospective Case Study
The Effect of Early Thyroidectomy on the Course of Active Graves’ Orbitopathy (GO): A Retrospective Case Study Open
The aim of the work was to investigate the effect of early thyroidectomy on the course of active Graves' orbitopathy (GO) in patients with low probability of remission [high TSH receptor antibody (TRAb) serum levels, severe GO] compared to…