Pierpaolo Sorrentino
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View article: Role of criticality in the structure-function relationship in the human brain
Role of criticality in the structure-function relationship in the human brain Open
A healthy brain exhibits a rich dynamical repertoire, with flexible spatiotemporal patterns replaying on both microscopic and macroscopic scales. We hypothesize that the observed relationship between empirical structure and functional patt…
View article: Author response: Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms
Author response: Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms Open
View article: Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms
Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms Open
Signatures of consciousness are found in spectral and temporal properties of neuronal activity. Among these, spatiotemporal complexity after a perturbation has recently emerged as a robust metric to infer levels of consciousness. Perturbat…
View article: Author response: Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms
Author response: Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms Open
View article: Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms
Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms Open
Signatures of consciousness are found in spectral and temporal properties of neuronal activity. Among these, spatiotemporal complexity after a perturbation has recently emerged as a robust metric to infer levels of consciousness. Perturbat…
View article: Next generation neural mass model with dopamine modulation mediated by D1-type receptors
Next generation neural mass model with dopamine modulation mediated by D1-type receptors Open
Neuromodulation is a complex process in which chemical substances modulate brain activity, allowing its rich repertoire of behaviors. Among these substances, dopamine has a preponderant role, being involved in several mechanisms. Moreover,…
View article: Superconducting Quantum Magnetometers for Brain Investigations
Superconducting Quantum Magnetometers for Brain Investigations Open
This review article aims to provide an overview of superconducting magnetic quantum sensors and their applications in the biomedical field, particularly in the neurological field. These quantum sensors are based on superconducting quantum …
View article: Beta Burst Waveform Motifs Link Cortico-Subcortical Connectivity and Clinical Improvement in Parkinson’s Disease
Beta Burst Waveform Motifs Link Cortico-Subcortical Connectivity and Clinical Improvement in Parkinson’s Disease Open
Beta bursts are increasingly being studied as biomarkers of Parkinson’s disease (PD) symptoms and therapeutic response. While most prior work has focused on time-frequency burst features such as duration or amplitude, recent evidence sugge…
View article: Brain Fluidity as a Functional Marker of Tau-Related Neurodegeneration in Alzheimer’s Disease
Brain Fluidity as a Functional Marker of Tau-Related Neurodegeneration in Alzheimer’s Disease Open
Alzheimer’s Disease (AD) is the most common form of dementia and one of the leading neurodegenerative disorders worldwide. Neurophysiopathologically, AD is characterized by neuronal death, accompanied by the alteration of tau protein in th…
View article: The Effects of Aging and Cognition on Gait Coordination Analyzed Through a Network Analysis Approach
The Effects of Aging and Cognition on Gait Coordination Analyzed Through a Network Analysis Approach Open
Background/Objectives: Walking coordination is crucial for maintaining independence and quality of life, but it is significantly affected by aging and cognitive decline. This study investigates how age and cognitive status relate to lower …
View article: L-Dopa-induced changes in aperiodic bursts dynamics relate to individual clinical improvement in Parkinson’s disease
L-Dopa-induced changes in aperiodic bursts dynamics relate to individual clinical improvement in Parkinson’s disease Open
Parkinson’s disease (PD) is a neurodegenerative disease characterized by severe motor symptoms, transiently alleviated by medication (e.g. levodopa), and widespread brain activity alterations that remain poorly understood at a large scale …
View article: Neuronal avalanches as a predictive biomarker of BCI performance: towards a tool to guide tailored training program
Neuronal avalanches as a predictive biomarker of BCI performance: towards a tool to guide tailored training program Open
Brain-Computer Interfaces (BCIs) based on motor imagery (MI) hold promise for restoring control in individuals with motor impairments. However, up to 30% of users remain unable to effectively use BCIs-a phenomenon termed ''BCI inefficiency…
View article: Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs
Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs Open
Motor imagery-based Brain-Computer Interfaces (BCIs) restore control in persons with motor impairments, but up to 30% of users struggle—a phenomenon known as “BCI inefficiency”. This study tackles a key limitation of current protocol: the …
View article: The Effects of Aging and Cognition on Gait Coordination Analyzed Through a Network Analysis Approach
The Effects of Aging and Cognition on Gait Coordination Analyzed Through a Network Analysis Approach Open
Background/Objectives: This study investigates how age and cognitive status relate to lower limb coordination during gait, using a network-based analysis of joint kinematics. Methods: Fifty-six healthy participants underwent gait analysis …
View article: Mapping Brain Lesions to Conduction Delays: The Next Step for Personalized Brain Models in Multiple Sclerosis
Mapping Brain Lesions to Conduction Delays: The Next Step for Personalized Brain Models in Multiple Sclerosis Open
Multiple sclerosis (MS) is a clinically heterogeneous, multifactorial autoimmune disorder affecting the central nervous system. Structural damage to the myelin sheath, resulting in the consequent slowing of the conduction velocities, is a …
View article: Magnetoencephalography Dimensionality Reduction Informed by Dynamic Brain States
Magnetoencephalography Dimensionality Reduction Informed by Dynamic Brain States Open
Complex spontaneous brain dynamics mirror the large number of interactions taking place among regions, supporting higher functions. Such complexity is manifested in the interregional dependencies among signals derived from different brain …
View article: The Virtual Parkinsonian patient
The Virtual Parkinsonian patient Open
This study investigates the influence of the pharmacological nigrostriatal dopaminergic stimulation on the entire brain by analyzing EEG and deep electrodes, placed near the subthalamic nuclei, from 10 Parkinsonian patients before (OFF) an…
View article: Mapping global brain reconfigurations following local targeted manipulations
Mapping global brain reconfigurations following local targeted manipulations Open
Understanding how localized brain interventions influence whole-brain dynamics is essential for deciphering neural function and designing therapeutic strategies. Using longitudinal functional MRI datasets collected from mice, we investigat…
View article: Artificial Intelligence for automatic movement recognition: a network-based approach
Artificial Intelligence for automatic movement recognition: a network-based approach Open
Introduction automatic movement recognition is often used to support various fields such as clinical, sports, and security. To date, there is a lack of a classification feature that is both interpretable and not movement-specific, characte…
View article: Analyzing Information Exchange in Parkinson’s Disease via Eigenvector Centrality: A Source-Level Magnetoencephalography Study
Analyzing Information Exchange in Parkinson’s Disease via Eigenvector Centrality: A Source-Level Magnetoencephalography Study Open
Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder that manifests through motor and non-motor symptoms. Understanding the alterations in brain connectivity associated with PD remains a challenge that is crucia…
View article: Intermodal Consistency of Whole‐Brain Connectivity and Signal Propagation Delays
Intermodal Consistency of Whole‐Brain Connectivity and Signal Propagation Delays Open
Measuring propagation of perturbations across the human brain and their transmission delays is critical for network neuroscience, but it is a challenging problem that still requires advancement. Here, we compare results from a recently int…
View article: Large-Scale Neural Dynamics as a Predictor of Stimulus Effects Variability
Large-Scale Neural Dynamics as a Predictor of Stimulus Effects Variability Open
View article: Principles and Operation of Virtual Brain Twins
Principles and Operation of Virtual Brain Twins Open
Current clinical methods often overlook individual variability by relying on population-wide trials, while mechanismbased trials remain underutilized in neuroscience due to the brain's complexity. This situation may change through the use …
View article: Brain fingerprint and subjective mood state across the menstrual cycle
Brain fingerprint and subjective mood state across the menstrual cycle Open
Background Brain connectome fingerprinting represents a recent and valid approach in assessing individual identifiability on the basis of the subject-specific brain functional connectome. Although this methodology has been tested and valid…
View article: Dynamic reconfiguration of aperiodic brain activity supports cognitive functioning in epilepsy: A neural fingerprint identification
Dynamic reconfiguration of aperiodic brain activity supports cognitive functioning in epilepsy: A neural fingerprint identification Open
View article: Complexity in speech and music listening via neural manifold flows
Complexity in speech and music listening via neural manifold flows Open
Understanding the complex neural mechanisms underlying speech and music perception remains a multifaceted challenge. In this study, we investigated neural dynamics using human intracranial recordings. Employing a novel approach based on lo…
View article: NEURONAL AVALANCHES FOR EEG-BASED MOTOR IMAGERY BCI
NEURONAL AVALANCHES FOR EEG-BASED MOTOR IMAGERY BCI Open
General Proceeding DOI: https://doi.org/10.3217/978-3-85125-682-6Personal paper DOI: https://doi.org/10.3217/978-3-99161-014-4-018 (not yet activated)
View article: Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms
Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms Open
Signatures of consciousness are found in spectral and temporal properties of neuronal activity. Among these, spatiotemporal complexity after a perturbation has recently emerged as a robust metric to infer levels of consciousness. Perturbat…
View article: Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms
Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms Open
Signatures of consciousness are found in spectral and temporal properties of neuronal activity. Among these, spatiotemporal complexity after a perturbation has recently emerged as a robust metric to infer levels of consciousness. Perturbat…
View article: Magnetoencephalography dimensionality reduction informed by dynamic brain states
Magnetoencephalography dimensionality reduction informed by dynamic brain states Open
Complex spontaneous brain dynamics mirror the large number of interactions taking place among regions, supporting higher functions. Such complexity is manifested in the inter-regional dependencies among signals derived from different brain…