Pierre Gelin
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View article: Enhanced Acoustic Mixing in Silicon-Based Chips with Sharp-Edged Micro-Structures
Enhanced Acoustic Mixing in Silicon-Based Chips with Sharp-Edged Micro-Structures Open
The small dimensions of microfluidic channels allow for fast diffusive or passive mixing, which is beneficial for time-sensitive applications such as chemical reactions, biological assays, and the transport of to-be-detected species to sen…
View article: A numerical study of the effects of lateral flow and retention in open tubular vortex chromatography
A numerical study of the effects of lateral flow and retention in open tubular vortex chromatography Open
Axial dispersion in chromatographic columns is responsible for a reduced separation efficiency. In the present research macrotransport theory is used to predict the phenomenological constants related to axial dispersion. We evaluate the ef…
View article: Enhanced Acoustic Mixing in Silicon-Based Chips with Sharp-Edged Micro-Structures
Enhanced Acoustic Mixing in Silicon-Based Chips with Sharp-Edged Micro-Structures Open
The small dimensions of microfluidic channels allow for fast diffusive or passive mixing, which is beneficial for time-sensitive applications such as chemical reactions, biological assays, and the transport of to-be-detected species to sen…
View article: An opto-acousto-fluidic microchip for efficient Raman spectroscopy of microparticles in aqueous environment
An opto-acousto-fluidic microchip for efficient Raman spectroscopy of microparticles in aqueous environment Open
2-D and 3-D Raman mapping are powerful imaging techniques for creating chemical images and compositional analysis of materials. Nevertheless, integration and implementation of Raman mapping on a microfluidic system turns out to be arduous …
View article: Characterizing Acoustic Behavior of Silicon Microchannels Separated by a Porous Wall
Characterizing Acoustic Behavior of Silicon Microchannels Separated by a Porous Wall Open
Lateral flow membrane microdevices are widely used for chromatographic separation processes and diagnostics. The separation performance of microfluidic lateral membrane devices is determined by mass transfer limitations in the membrane, an…
View article: Exploring operational boundaries for acoustic concentration of cell suspensions
Exploring operational boundaries for acoustic concentration of cell suspensions Open
The development of a standardized, generic method for concentrating suspensions in continuous flow is challenging. In this study, we developed and tested a device capable of concentrating suspensions with an already high cell concentration…
View article: Enhanced Performance of an Acoustofluidic Device by Integrating Temperature Control
Enhanced Performance of an Acoustofluidic Device by Integrating Temperature Control Open
Acoustofluidics is an emerging research field wherein either mixing or (bio)-particle separation is conducted. High-power acoustic streaming can produce more intense and rapid flow patterns, leading to faster and more efficient liquid mixi…
View article: Selecting active matter according to motility in an acoustofluidic setup: self-propelled particles and sperm cells
Selecting active matter according to motility in an acoustofluidic setup: self-propelled particles and sperm cells Open
Selecting sperm cells or self-propelled Janus particles according to their motility in an acoustofluidic setup: the acoustic trap focuses cells/particles near the channel centerline, and motile species escape the trap and can be collected …
View article: Rail induced lateral migration of particles across intact co-flowing liquids
Rail induced lateral migration of particles across intact co-flowing liquids Open
This paper presents a rail guided method to apply a Layer-by-Layer (LbL) coating on particles in a microfluidic device. The passive microfluidic approach allows handling suspensions of particles to be coated in the system. The trajectory o…
View article: Influence of Centrifugation and Shaking on the Self-Assembly of Lysozyme Fibrils
Influence of Centrifugation and Shaking on the Self-Assembly of Lysozyme Fibrils Open
Protein self-assembly into fibrils and oligomers plays a key role in the etiology of degenerative diseases. Several pathways for this self-assembly process have been described and shown to result in different types and ratios of final asse…
View article: Rail induced lateral migration of particles across intact co-flowing liquids
Rail induced lateral migration of particles across intact co-flowing liquids Open
This paper presents a rail guided method to apply Layer-by-Layer (LbL) coating on particles in a microfluidic device. The passive, microfluidic approach allows handling suspensions of particles to be coated in the system. The trajectory of…
View article: The Effect of Controlled Mixing on ROY Polymorphism
The Effect of Controlled Mixing on ROY Polymorphism Open
We report the investigation of various experimental conditions and their influence on polymorphism of 5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile, commonly known as ROY. These conditions include an in-house-developed microflu…
View article: Performance of laterally elongated pillar array columns in capillary electrochromatography mode
Performance of laterally elongated pillar array columns in capillary electrochromatography mode Open
In the present study, cylindrical and laterally elongated pillar array columns were investigated for use in capillary electrochromatography. Minimal theoretical plate heights of H = 1.90 and 1.46 μm (in absence of sidewall effect) were obt…
View article: Influence of Shear on Protein Crystallization under Constant Shear Conditions
Influence of Shear on Protein Crystallization under Constant Shear Conditions Open
A novel microfluidic device that subjects a solution to a constant shear flow was developed. By taking advantage of the linear velocity profile in a lid driven flow configuration, small volumes (10-5 L) can be subjected to a constant shear…
View article: Study on the mixing and migration behavior of micron-size particles in acoustofluidics
Study on the mixing and migration behavior of micron-size particles in acoustofluidics Open
Slow mass transfer remains a limiting factor in microfluidic devices, as it is purely based on molecular diffusion. Hence, the completion of a targeted chemical reaction is extremely slow. Acoustic streaming is a great methodology to creat…
View article: Focusing of Microcrystals and Liquid Condensates in Acoustofluidics
Focusing of Microcrystals and Liquid Condensates in Acoustofluidics Open
Manipulation of high-density materials, such as crystals and liquid condensates, is of great importance for many applications, including serial crystallography, structural and molecular biology, chemistry, and medicine. In this work, we de…
View article: Intensified Biobutanol Recovery by using Zeolites with Complementary Selectivity
Intensified Biobutanol Recovery by using Zeolites with Complementary Selectivity Open
A vapor‐phase adsorptive recovery process is proposed as an alternative way to isolate biobutanol from acetone–butanol–ethanol (ABE) fermentation media, offering several advantages compared to liquid phase separation. The effect of water, …