Pierre Hélie
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View article: Clinical and pathological findings in giraffes ( <i>Giraffa camelopardalis</i> ) with arterial thrombotic disease
Clinical and pathological findings in giraffes ( <i>Giraffa camelopardalis</i> ) with arterial thrombotic disease Open
Two adult female giraffes ( Giraffa camelopardalis ) from separate facilities were diagnosed with arterial thrombotic disease. The first giraffe presented with acute severe unilateral hindlimb paralysis. Infrared thermography revealed a ma…
View article: Bovine abortions due to the rare <i>Salmonella</i> serovars Kingston and Kedougou
Bovine abortions due to the rare <i>Salmonella</i> serovars Kingston and Kedougou Open
Two aborted bovine fetuses were submitted (6 mo apart) with portions of their chorioallantois for postmortem examination. In both cases, microscopic examination revealed large numbers of gram-negative bacilli in the chorionic vessels and, …
View article: Clinical, imaging and histopathological characterization of a series of three cats with cerebellar cortical degeneration
Clinical, imaging and histopathological characterization of a series of three cats with cerebellar cortical degeneration Open
Background Neurological inherited disorders are rare in domestic animals. Cerebellar cortical degeneration remains amongst the most common of these disorders. The condition is defined as the premature loss of fully differentiated cerebella…
View article: B- and T-cell lymphocytes and other immune cell infiltration in the duodenal and rectal mucosa of severe asthmatic horses
B- and T-cell lymphocytes and other immune cell infiltration in the duodenal and rectal mucosa of severe asthmatic horses Open
OBJECTIVE The objectives of this study were to quantify lymphocytes and eosinophils in the mucosa of the duodenum and rectum in asthmatic horses. ANIMALS 8 healthy and 10 asthmatic horses. PROCEDURES Asthmatic horses were evaluated in a sy…
View article: Inter-Rater Reliability of Scoring Systems for Abomasal Lesions in Quebec Veal Calves
Inter-Rater Reliability of Scoring Systems for Abomasal Lesions in Quebec Veal Calves Open
The objective of this study was to determine the inter-rater reliability of current scoring systems used to detect abomasal lesions in veal calves. In addition, macroscopic lesions were compared with corresponding histological lesions. For…
View article: Effects of azithromycin on bronchial remodeling in the natural model of severe neutrophilic asthma in horses
Effects of azithromycin on bronchial remodeling in the natural model of severe neutrophilic asthma in horses Open
View article: A Liquid Hydrogel to Restore Long Term Corneal Integrity After Perforating and Non-Perforating Trauma in Feline Eyes
A Liquid Hydrogel to Restore Long Term Corneal Integrity After Perforating and Non-Perforating Trauma in Feline Eyes Open
Purpose: To evaluate long-term in vivo functionality of corneas regenerated using a cell-free, liquid hydrogel filler (LiQD Cornea) after deep corneal trauma in the feline model. Methods: Two healthy cats underwent 4 mm diameter stepwise 2…
View article: Airway remodeling in horses with mild and moderate asthma
Airway remodeling in horses with mild and moderate asthma Open
Background There is a remodeling of the central airways in horses with severe asthma but whether a similar process occurs in horses with the mild or moderate asthma (MMA) is unknown. Objectives To evaluate lesions affecting the central air…
View article: Molecular characterization of <i>Mycobacterium avium</i> subspecies <i>paratuberculosis</i> C-type and S-type isolated from sheep and goats by using a combination of MIRU-VNTR loci.
Molecular characterization of <i>Mycobacterium avium</i> subspecies <i>paratuberculosis</i> C-type and S-type isolated from sheep and goats by using a combination of MIRU-VNTR loci. Open
Mycobacterium avium subspecies paratuberculosis (Map) is the etiological agent of paratuberculosis of domestic and wild ruminants. Map strains are segregated into 2 main groups or strain types referred to as sheep (S) type an…
View article: Validation of an in-house real-time PCR fecal assay and comparison with two commercial assays for the antemortem detection of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> infection in culled sheep
Validation of an in-house real-time PCR fecal assay and comparison with two commercial assays for the antemortem detection of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> infection in culled sheep Open
Paratuberculosis is a chronic infectious enteritis of ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). In sheep, the antemortem detection of the infection is challenging given the slow progression of the disease and t…
View article: Chondroblastic osteosarcoma of the middle ear in a guinea pig <i>(Cavia porcellus)</i>.
Chondroblastic osteosarcoma of the middle ear in a guinea pig <i>(Cavia porcellus)</i>. Open
A 3-year-old intact female guinea pig (Cavia porcellus) was presented for acute anorexia. Medical and surgical treatments for cystitis and ovarian cysts, respectively, did not prevent continuous weight loss. Computed tomography and …
View article: Retrobulbar malignant peripheral nerve sheath tumor in a golden retriever dog: A challenging diagnosis.
Retrobulbar malignant peripheral nerve sheath tumor in a golden retriever dog: A challenging diagnosis. Open
A 9-year-old golden retriever dog was diagnosed with a left retrobulbar mass. Fine-needle aspirations and incisional biopsies resulted in discordant diagnoses: myxosarcoma/myxoma or rhadomyosarcoma, respectively. Immunohistochemistry follo…
View article: Bronchoalveolar lavage fluid neutrophilia is associated with the severity of pulmonary lesions during equine asthma exacerbations
Bronchoalveolar lavage fluid neutrophilia is associated with the severity of pulmonary lesions during equine asthma exacerbations Open
Summary Background The severe form of equine asthma is associated with pathological changes of the peripheral airways and pulmonary parenchyma that are only partly described. Also, the relationship between these structural alterations and …
View article: Acute hepatic steatosis: a helpful diagnostic feature in metallic phosphide–poisoned horses
Acute hepatic steatosis: a helpful diagnostic feature in metallic phosphide–poisoned horses Open
Metal phosphides, particularly zinc and aluminum phosphide, occasionally poison horses and other equids following their use as rodenticides and insecticides. Grain-based aluminum phosphide baits are used to control rodents such as prairie …
View article: Pyelonephritis in Dogs: Retrospective Study of 47 Histologically Diagnosed Cases (2005–2015)
Pyelonephritis in Dogs: Retrospective Study of 47 Histologically Diagnosed Cases (2005–2015) Open
Background The clinicopathologic aspects of pyelonephritis have not been reported in companion animals. Hypothesis/Objectives To evaluate the prevalence of pyelonephritis diagnosed in dogs in a academic referral population, describe the cl…
View article: Effects of fentanyl on pain and motor behaviors following a collagenase-induced intracerebral hemorrhage in rats
Effects of fentanyl on pain and motor behaviors following a collagenase-induced intracerebral hemorrhage in rats Open
Fentanyl, at a dose of 10 µg/kg SC, provides substantial analgesia following a collagenase-induced IH in rats; however, it can alter motor performance following analgesic treatments.
View article: Development of a Semiquantitative Histological Score for the Diagnosis of Heaves Using Endobronchial Biopsy Specimens in Horses
Development of a Semiquantitative Histological Score for the Diagnosis of Heaves Using Endobronchial Biopsy Specimens in Horses Open
Background Remodeling of the peripheral airways persists during the asymptomatic phase of heaves. Assessing the histology of large bronchi could facilitate the diagnosis of heaves during remission of the disease. Hypothesis Airway inflamma…
View article: Physiological and pharmacokinetic effects of multilevel caging on Sprague Dawley rats under ketamine-xylazine anesthesia
Physiological and pharmacokinetic effects of multilevel caging on Sprague Dawley rats under ketamine-xylazine anesthesia Open
While the cage refinement is a necessary step towards improving the welfare of research\nrats, increasing the complexity and surface area of the living space of an animal may have\nphysiological impacts that need to be taken into considera…
View article: Physiological, pharmacokinetic and liver metabolism comparisons between 3-, 6-, 12- and 18-month-old male Sprague Dawley rats under ketamine-xylazine anesthesia
Physiological, pharmacokinetic and liver metabolism comparisons between 3-, 6-, 12- and 18-month-old male Sprague Dawley rats under ketamine-xylazine anesthesia Open
The main objective of this study was to compare the physiological changes (withdrawal and corneal reflexes, respiratory and cardiac frequency, blood oxygen saturation, and rectal temperature) following intraperitoneal administration of ket…
View article: Comparative study of 2 surgical techniques for castration of guinea pigs (Cavia porcellus).
Comparative study of 2 surgical techniques for castration of guinea pigs (Cavia porcellus). Open
The objective of this study was to compare 2 surgical approaches (scrotal or abdominal) for castration of guinea pigs and to investigate post-operative infection rates with either technique. Forty-eight guinea pigs were castrated by scrota…
View article: Anesthetic and pathological changes following high doses of ketamine and xylazine in Sprague Dawley rats
Anesthetic and pathological changes following high doses of ketamine and xylazine in Sprague Dawley rats Open
The main objective of this study was to compare the effects of ketamine and xylazine in aging rats when coadministered intraperitoneally at high anesthetic doses. Three groups (n=6 rats/group) consisting of rats at 3, 6 and 12 months of ag…
View article: Abdominal Distension Associated with Luminal Fungi in the Intestines of Axolotl Larvae
Abdominal Distension Associated with Luminal Fungi in the Intestines of Axolotl Larvae Open
Axolotls show a remarkable regeneration capacity compared with higher vertebrates, regenerating missing appendages such as limbs and tail as well as other body parts (i.e., apex of the heart, forebrain, and jaw) after amputations which mak…
View article: Characterisation of the clinical importance of porcine group C rotavirus in a swine nursery production network in Quebec
Characterisation of the clinical importance of porcine group C rotavirus in a swine nursery production network in Quebec Open
Enteric infectious diseases in swine have considerable economic impact on the industry due either to mortality, cost of treatment or reduced growth rates which can lead to extended production periods. The consequences can be catastrophic e…