Pierre Senée
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View article: Revealing neurovascular coupling at a high spatial and temporal resolution in the living human retina
Revealing neurovascular coupling at a high spatial and temporal resolution in the living human retina Open
Neurovascular coupling (NVC) regulates local blood flow in response to neuronal activity, yet its precise characterization at the capillary level has been hindered by the lack of a noninvasive, high-resolution imaging method. Here, we intr…
View article: Adaptive Optics Rolling Slit Ophthalmoscope: Combining cellular-resolution, high-speed and large field-of-view in a multimodal retinal imager
Adaptive Optics Rolling Slit Ophthalmoscope: Combining cellular-resolution, high-speed and large field-of-view in a multimodal retinal imager Open
Label-free optical imaging systems capable of monitoring dynamic biological processes over a large field-of-view (FOV) are essential for advancing our understanding of retinal and neurovascular health. However, existing imaging modalities …
View article: Measuring flicker induced vasodilation at a high spatial and temporal resolution in the human retina
Measuring flicker induced vasodilation at a high spatial and temporal resolution in the human retina Open
Neurovascular coupling (NVC) is a crucial process in which blood flow is dynamically adjusted to meet the metabolic demands of active neurons. In this study, we introduce an innovative method for in-vivo imaging of retinal blood vessel dil…
View article: High-contrast and high-speed multimodal imaging platform: the adaptive optics-confocal rolling slit ophthalmoscope (AO-CRSO)
High-contrast and high-speed multimodal imaging platform: the adaptive optics-confocal rolling slit ophthalmoscope (AO-CRSO) Open
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View article: Multimodal high-resolution retinal imaging using camera-based DMD-integrated Adaptive Optics Flood-Illumination Ophthalmoscope
Multimodal high-resolution retinal imaging using camera-based DMD-integrated Adaptive Optics Flood-Illumination Ophthalmoscope Open
We demonstrate the feasibility of a multimodal adaptive optics flood-illumination ophthalmoscope, able to provide both bright-field and dark-field images (such as phase contrast). The multimodality was made possible by integrating a DMD at…