Pierre Solomon
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View article: Artificial intelligence driven tumor risk stratification from single-cell transcriptomics using phenotype algebra
Artificial intelligence driven tumor risk stratification from single-cell transcriptomics using phenotype algebra Open
Single-cell RNA-sequencing (scRNA-seq) coupled with robust computational analysis facilitates the characterization of phenotypic heterogeneity within tumors. Current scRNA-seq analysis pipelines are capable of identifying a myriad of malig…
View article: Disease severity across psychiatric disorders is linked to pro-inflammatory cytokines
Disease severity across psychiatric disorders is linked to pro-inflammatory cytokines Open
The observed differences in serum protein expression suggest that disease severity is associated with the convergence of immune system dysregulation and neurodevelopmental alterations, particularly involving pathways related to inflammatio…
View article: Integrative analysis of miRNA expression profiles reveals distinct and common molecular mechanisms underlying broad diagnostic groups of severe mental disorders
Integrative analysis of miRNA expression profiles reveals distinct and common molecular mechanisms underlying broad diagnostic groups of severe mental disorders Open
Micro RNAs (miRNAs) play a crucial role as regulators of various biological processes and have been implicated in the pathogenesis of mental disorders such as schizophrenia and bipolar disorders. In this study, we investigate the expressio…
View article: SCellBOW: AI-Driven Tumor Risk Stratification from Single-Cell Transcriptomics Using Phenotype Algebra
SCellBOW: AI-Driven Tumor Risk Stratification from Single-Cell Transcriptomics Using Phenotype Algebra Open
Single-cell RNA-sequencing (scRNA-seq) coupled with robust computational analysis facilitates the characterization of phenotypic heterogeneity within tumors. Current scRNA-seq analysis pipelines are capable of identifying a myriad of malig…
View article: Disease Severity Across Psychiatric Disorders Is Linked to Pro-Inflammatory Cytokines
Disease Severity Across Psychiatric Disorders Is Linked to Pro-Inflammatory Cytokines Open
Importance Numerous studies indicate that the traditional categorical classification of severe mental disorders (SMD), such as schizophrenia, bipolar disorders, and major depressive disorders, does not align with the underlying biology of …
View article: Artificial intelligence driven tumor risk stratification from single-cell transcriptomics using phenotype algebra
Artificial intelligence driven tumor risk stratification from single-cell transcriptomics using phenotype algebra Open
Single-cell RNA-sequencing (scRNA-seq) coupled with robust computational analysis facilitates the characterization of phenotypic heterogeneity within tumors. Current scRNA-seq analysis pipelines are capable of identifying a myriad of malig…
View article: Pseudo-grading of tumor subpopulations from single-cell transcriptomic data using Phenotype Algebra
Pseudo-grading of tumor subpopulations from single-cell transcriptomic data using Phenotype Algebra Open
Single-cell RNA-sequencing (scRNA-seq) coupled with robust computational analysis facilitates the characterization of phenotypic heterogeneity within tumors. Current scRNA-seq analysis pipelines are capable of identifying a myriad of malig…
View article: Integrative Analysis of miRNA Expression Profiles Reveals Distinct and Common Molecular Mechanisms Underlying Broad Diagnostic Groups of Severe Mental Disorders
Integrative Analysis of miRNA Expression Profiles Reveals Distinct and Common Molecular Mechanisms Underlying Broad Diagnostic Groups of Severe Mental Disorders Open
Micro RNAs (miRNAs) play a crucial role as regulators of various biological processes and have been implicated in the pathogenesis of mental disorders such as schizophrenia and bipolar disorders. In this study, we investigate the expressio…
View article: F86. INTEGRATIVE ANALYSIS OF MICRORNA EXPRESSION PROFILES REVEALS POTENTIAL MOLECULAR MECHANISMS UNDERLYING BROAD DIAGNOSTIC GROUPS
F86. INTEGRATIVE ANALYSIS OF MICRORNA EXPRESSION PROFILES REVEALS POTENTIAL MOLECULAR MECHANISMS UNDERLYING BROAD DIAGNOSTIC GROUPS Open
Micro RNAs (miRNAs) play a crucial role as regulators of various biological processes and have been implicated in the pathogenesis of mental disorders such as schizophrenia and bipolar disorders. In this study, we investigate the expressio…
View article: SCellBOW: AI-Driven Tumor Risk Stratification from Single-Cell Transcriptomics Using Phenotype Algebra
SCellBOW: AI-Driven Tumor Risk Stratification from Single-Cell Transcriptomics Using Phenotype Algebra Open
Single-cell RNA-sequencing (scRNA-seq) coupled with robust computational analysis facilitates the characterization of phenotypic heterogeneity within tumors. Current scRNA-seq analysis pipelines are capable of identifying a myriad of malig…
View article: Cystathionine‐gamma‐lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy
Cystathionine‐gamma‐lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy Open
T cells could be engineered to overcome the aberrant metabolic milieu of solid tumors and tip the balance in favor of a long‐lasting clinical response. Here, we explored the therapeutic potential of stably overexpressing cystathionine‐gamm…