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View article: Systematic evaluation of abdominal aortic calcification in patients with a recent clinical fracture visiting the Fracture Liaison Service
Systematic evaluation of abdominal aortic calcification in patients with a recent clinical fracture visiting the Fracture Liaison Service Open
View article: Family-based whole-exome sequencing implicates a variant in lysyl oxidase like 4 in atypical femur fractures
Family-based whole-exome sequencing implicates a variant in lysyl oxidase like 4 in atypical femur fractures Open
Atypical femur fractures (AFFs) are rare adverse events associated with bisphosphonate use, having unclear pathophysiology. AFFs also cluster in families and have occurred in patients with monogenetic bone diseases sometimes without bispho…
View article: The Fracture Phenotypes in Women and Men of 50 Years and Older with a Recent Clinical Fracture
The Fracture Phenotypes in Women and Men of 50 Years and Older with a Recent Clinical Fracture Open
View article: Bone microarchitecture and strength assessed by HRpQCT in individuals with type 2 diabetes and prediabetes: the Maastricht study
Bone microarchitecture and strength assessed by HRpQCT in individuals with type 2 diabetes and prediabetes: the Maastricht study Open
Type 2 diabetes (T2D) is a prevalent disease and has been associated with an increased fracture risk despite normal or even higher areal BMD. The aim of this study was to estimate the association between glucose metabolism status (GMS) and…
View article: Follow-up in Fracture Liaisons Services: the involvement of general practitioners and fracture nurses is urgently needed
Follow-up in Fracture Liaisons Services: the involvement of general practitioners and fracture nurses is urgently needed Open
View article: The Dutch multidisciplinary guideline osteoporosis and fracture prevention, taking a local guideline to the international arena
The Dutch multidisciplinary guideline osteoporosis and fracture prevention, taking a local guideline to the international arena Open
View article: Characterizing Bone Phenotypes Related to Skeletal Fragility Using Advanced Medical Imaging
Characterizing Bone Phenotypes Related to Skeletal Fragility Using Advanced Medical Imaging Open
Purpose of Review Summarize the recent literature that investigates how advanced medical imaging has contributed to our understanding of skeletal phenotypes and fracture risk across the lifespan. Recent Findings Characterization of bone ph…
View article: The contribution of lower-mineralized tissue to the healing of distal radius fractures assessed using HR-pQCT
The contribution of lower-mineralized tissue to the healing of distal radius fractures assessed using HR-pQCT Open
High-resolution peripheral quantitative CT (HR-pQCT) enables quantitative assessment of distal radius fracture healing. In previous studies, lower-mineralized tissue formation was observed on HR-pQCT scans, starting early during healing, b…
View article: AB0092 ANTIBODIES OF THE IMMUNOGLOBULIN G AND A ISOTYPE TO NOVEL PEPTIDES IN EARLY AXIAL SPONDYLOARTHRITIS PATIENTS
AB0092 ANTIBODIES OF THE IMMUNOGLOBULIN G AND A ISOTYPE TO NOVEL PEPTIDES IN EARLY AXIAL SPONDYLOARTHRITIS PATIENTS Open
View article: OP0129 EFFECTIVENESS OF COBRA-SLIM WITH OR WITHOUT EARLY ACCESS TO A TEMPORARY 6-MONTH COURSE OF ETANERCEPT IN EARLY RA: PRIMARY OUTCOME OF THE 2-YEAR, PRAGMATIC, RANDOMISED CARERA2020 TRIAL
OP0129 EFFECTIVENESS OF COBRA-SLIM WITH OR WITHOUT EARLY ACCESS TO A TEMPORARY 6-MONTH COURSE OF ETANERCEPT IN EARLY RA: PRIMARY OUTCOME OF THE 2-YEAR, PRAGMATIC, RANDOMISED CARERA2020 TRIAL Open
BACKGROUND: EULAR recommends methotrexate (MTX), combined with shortterm glucocorticoids as first-line treatment for early Rheumatoid Arthritis (RA). In the CareRA trial, the COBRA-Slim regimen (MTX 15 mg/w + step-down prednisone 30, 20, 1…
View article: High Frequency of Foot Insufficiency Fractures in Patients With Rheumatic Diseases Referred for Magnetic Resonance Imaging: What Is the Clinical Relevance?
High Frequency of Foot Insufficiency Fractures in Patients With Rheumatic Diseases Referred for Magnetic Resonance Imaging: What Is the Clinical Relevance? Open
We greatly appreciated the manuscript by Björn Buehring et al1 about the high prevalence of foot insufficiency fractures (IFs) in patients with inflammatory rheumatic and musculoskeletal diseases (RMDs) who were referred for mag…
View article: Romosozumab for the treatment of postmenopausal women at high risk of fracture
Romosozumab for the treatment of postmenopausal women at high risk of fracture Open
Compared to antiresorptive agents, its unique mechanism of action results in a quicker and greater increase in bone mineral density, it repairs and restores trabecular and cortical bone microarchitecture, and reduces fracture risk more rap…
View article: Association of Multimorbidity and Excess Mortality After Fractures Among Danish Adults
Association of Multimorbidity and Excess Mortality After Fractures Among Danish Adults Open
Importance Limited knowledge about interactions among health disorders impedes optimal patient care. Because comorbidities are common among patients 50 years and older with fractures, these fractures provide a useful setting for studying i…
View article: What Is the Diagnostic Performance of Conventional Radiographs and Clinical Reassessment Compared With HR-pQCT Scaphoid Fracture Diagnosis?
What Is the Diagnostic Performance of Conventional Radiographs and Clinical Reassessment Compared With HR-pQCT Scaphoid Fracture Diagnosis? Open
Background Conventional radiographs and clinical reassessment are considered guides in managing clinically suspected scaphoid fractures. This is a unique study as it assessed the value of conventional radiographs and clinical reassessment …
View article: Association between incident falls and subsequent fractures in patients attending the fracture liaison service after an index fracture: a 3-year prospective observational cohort study
Association between incident falls and subsequent fractures in patients attending the fracture liaison service after an index fracture: a 3-year prospective observational cohort study Open
Objectives To evaluate the risk of subsequent fractures in patients who attended the Fracture Liaison Service (FLS), with and without incident falls after the index fracture. Design A 3-year prospective observational cohort study. Setting …
View article: How to implement guidelines and models of care
How to implement guidelines and models of care Open
View article: Prevalent Morphometrically Assessed Vertebral Fractures in Individuals With Type 2 Diabetes, Prediabetes and Normal Glucose Metabolism: The Maastricht Study
Prevalent Morphometrically Assessed Vertebral Fractures in Individuals With Type 2 Diabetes, Prediabetes and Normal Glucose Metabolism: The Maastricht Study Open
Background Type 2 diabetes (T2D) is frequently reported to be associated with an increased fracture risk. Epidemiological data on prevalent morphometric vertebral fractures (VFs) in T2D are sparse and even less is known in the prediabetic …
View article: The fracture liaison service, a step forward not only in fracture reduction, but also in mortality reduction
The fracture liaison service, a step forward not only in fracture reduction, but also in mortality reduction Open
View article: The Effect of Discontinuing Denosumab in Patients With Rheumatoid Arthritis Treated With Glucocorticoids
The Effect of Discontinuing Denosumab in Patients With Rheumatoid Arthritis Treated With Glucocorticoids Open
Objective To evaluate changes in bone turnover and bone mineral density (BMD) in patients with rheumatoid arthritis (RA) receiving glucocorticoids, after discontinuation of denosumab for 12 months. Methods We conducted a randomized, double…
View article: Association between bone shape and the presence of a fracture in patients with a clinically suspected scaphoid fracture
Association between bone shape and the presence of a fracture in patients with a clinically suspected scaphoid fracture Open
View article: Cognitive decline is associated with an accelerated rate of bone loss and increased fracture risk in women: a prospective study from the Canadian Multicentre Osteoporosis Study
Cognitive decline is associated with an accelerated rate of bone loss and increased fracture risk in women: a prospective study from the Canadian Multicentre Osteoporosis Study Open
Cognitive decline and osteoporosis often coexist and some evidence suggests a causal link. However, there are no data on the longitudinal relationship between cognitive decline, bone loss and fracture risk, independent of aging. This study…
View article: Associations between bone attenuation and prevalent vertebral fractures on chest CT scans differ with vertebral fracture locations
Associations between bone attenuation and prevalent vertebral fractures on chest CT scans differ with vertebral fracture locations Open
Clinicaltrials.gov identifier: NCT00292552.
View article: Decreased Mortality and Subsequent Fracture Risk in Patients With a Major and Hip Fracture After the Introduction of a Fracture Liaison Service: A 3-Year Follow-Up Survey
Decreased Mortality and Subsequent Fracture Risk in Patients With a Major and Hip Fracture After the Introduction of a Fracture Liaison Service: A 3-Year Follow-Up Survey Open
Fracture liaison services (FLS) are considered to be the most effective organizational approach for secondary fracture prevention. In this study, we evaluated whether FLS care was associated with reduced subsequent fracture and mortality r…
View article: Effect of Denosumab Compared With Risedronate on Bone Strength in Patients Initiating or Continuing Glucocorticoid Treatment
Effect of Denosumab Compared With Risedronate on Bone Strength in Patients Initiating or Continuing Glucocorticoid Treatment Open
In a randomized clinical trial in patients initiating glucocorticoid therapy (GC-I) or on long-term therapy (GC-C), denosumab every 6 months increased spine and hip bone mineral density at 12 and 24 months significantly more than daily ris…
View article: The Effect of Bolus Vitamin D3 Supplementation on Distal Radius Fracture Healing: A Randomized Controlled Trial Using HR-pQCT
The Effect of Bolus Vitamin D3 Supplementation on Distal Radius Fracture Healing: A Randomized Controlled Trial Using HR-pQCT Open
Vitamin D is an important factor in bone metabolism. Animal studies have shown a positive effect of vitamin D3 supplementation on fracture healing, but evidence from clinical trials is inconclusive. A randomized controlled trial was perfor…
View article: Reply to: The Association Between Cognitive Decline and Bone Loss and Fracture Risk Is Not Affected by Medication With Anticholinergic Effect
Reply to: The Association Between Cognitive Decline and Bone Loss and Fracture Risk Is Not Affected by Medication With Anticholinergic Effect Open
To the Editors: We are grateful to Dr. Naharci for the interest in our study reporting the association between cognitive decline and bone loss and fracture risk. (1) We agree that bisphosphonates (BPs) have a proven effect on reducing bone…
View article: Association of secondary displacement of distal radius fractures with cortical bone quality at the distal radius
Association of secondary displacement of distal radius fractures with cortical bone quality at the distal radius Open
Introduction The aim of this study was to investigate the associations of patient characteristics, bone mineral density (BMD), bone microarchitecture and calculated bone strength with secondary displacement of a DRF based on radiographic a…
View article: Improved Detection of Scaphoid Fractures with High-Resolution Peripheral Quantitative CT Compared with Conventional CT
Improved Detection of Scaphoid Fractures with High-Resolution Peripheral Quantitative CT Compared with Conventional CT Open
Background: Computed tomography (CT), magnetic resonance imaging, and bone scintigraphy are second-line imaging techniques that are frequently used for the evaluation of patients with a clinically suspected scaphoid fracture. However, as a…
View article: Is a treat-to-target strategy in osteoporosis applicable in clinical practice? Consensus among a panel of European experts
Is a treat-to-target strategy in osteoporosis applicable in clinical practice? Consensus among a panel of European experts Open
View article: The Prevalence of Celiac Disease in a Fracture Liaison Service Population
The Prevalence of Celiac Disease in a Fracture Liaison Service Population Open