Pietro Andrei
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View article: Kandinsky: enabling neighbourhood analysis of spatial omics data for functional insights on cell ecosystems
Kandinsky: enabling neighbourhood analysis of spatial omics data for functional insights on cell ecosystems Open
A major breakthrough of spatial omics is the opportunity to investigate how cells interact within their local environment or neighbourhood and several computational methods have been developed to aid this analysis. However, significant lim…
View article: A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer
A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer Open
Fewer than 50% of metastatic deficient mismatch repair (dMMR) colorectal cancer (CRC) patients respond to immune checkpoint inhibition (ICI). Identifying and expanding this patient population remains a pressing clinical need. Here, we repo…
View article: Transcriptome‐wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer
Transcriptome‐wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer Open
Multiple strategies are continuously being explored to expand the drug target repertoire in solid tumors. We devised a novel computational workflow for transcriptome‐wide gene expression outlier analysis that allows the systematic identifi…
View article: Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer Open
Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
View article: Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer Open
Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
View article: Data from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Data from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer Open
Purpose:Genomic instability is a hallmark of cancer and targeting DNA damage response (DDR) is emerging as a promising therapeutic strategy in different solid tumors. The effectiveness of targeting DDR in colorectal cancer has not been ext…
View article: Supplementary Figure from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Supplementary Figure from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer Open
Supplementary Figure from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
View article: Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer Open
Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
View article: Data from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Data from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer Open
Purpose:Genomic instability is a hallmark of cancer and targeting DNA damage response (DDR) is emerging as a promising therapeutic strategy in different solid tumors. The effectiveness of targeting DDR in colorectal cancer has not been ext…
View article: Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer Open
Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
View article: Supplementary Figure from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Supplementary Figure from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer Open
Supplementary Figure from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
View article: Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer Open
Purpose: Genomic instability is a hallmark of cancer and targeting DNA damage response (DDR) is emerging as a promising therapeutic strategy in different solid tumors. The effectiveness of targeting DDR in colorectal cancer has not been ex…