Explanipedia

Clinical Characteristics, Symptoms, and Long-Term Outcomes in Gitelman Syndrome Open

Michiel L. A. J. Wieërs, Lise Allard, Viola D’Ambrosio, Pedro Arango-Sancho, Jeroen H. F. de Baaij , et al. · 2025

Meta-analysis of genome-wide association studies for cancer therapy-related cardiovascular dysfunction and functional mapping highlight an intergenic region close to TP63 Open

Laura Martínez-Campelo, Alejandro Blanco‐Verea, Teresa López‐Fernández, Amparo Martínez‐Monzonís, Antonio Buño Soto , et al. · 2024

Cancer therapy-related cardiac dysfunction (CTRCD), which commonly includes left ventricular dysfunction and heart failure, is the main adverse effect of anticancer therapy. In recent years several candidate genes studies and genome-wide a…

#1153 Short course of steroids as a treatment for immune checkpoint inhibitors-associated acute kidney injury Open

Teresa Cavero, Vanessa Lopes, Katherine Peña Ordoñez, Mara Serrano Soto, Mariana Rivera Pérez , et al. · 2024

Background and Aims Immune checkpoint inhibitors (ICPi) have been a revolution in oncology. Due to their mechanism of action they can produce inflammatory adverse events, called “immune related adverse events” (IrAEs). Immune-mediated rena…

Kidney Transplantation Outcomes of Patients With Chronic Hypotension in Dialysis Open

Pilar Auñón, Teresa Cavero, Ana Isabel Morales García, Jorge González, Amado Andrés · 2024

Chronic hypotension in dialysis has a negative impact on short-term kidney transplant outcomes but a lower impact on long-term results. It is reversible after receiving a functioning graft. Identifying this subgroup of patients seems cruci…

Rational use of eculizumab in secondary atypical hemolytic uremic syndrome Open

Lucía Cordero, Teresa Cavero, Eduardo Gutiérrez, Hernando Trujillo, Justo Sandino , et al. · 2024

Background Secondary atypical hemolytic uremic syndrome (secondary aHUS) is a heterogeneous group of thrombotic microangiopathies (TMA) associated with various underlying conditions. Unlike primary aHUS, there is still no hard evidence on …

Adverse renal effects of check-point inhibitors (ICI) in cancer patients: Recommendations of the Onco-nephrology Working Group of the Spanish Society of Nephrology Open

Fabiola Alonso, Ángel L.M. Martín de Francisco, Pilar Auñón, Clara García-Carro, Patricia García , et al. · 2023

The most widely used approach in the immunotherapy treatment of cancer is the administration of monoclonal antibodies directed against regulatory molecules of immune control that inhibit the activation of T cells, the so-called check point…

#5163 RATIONAL USE OF ECULIZUMAB IN SECONDARY ATYPICAL HAEMOLYTIC UREMIC SYNDROME Open

Lucía Cordero García-Galán, Teresa Cavero, Eduardo Gutiérrez, Justo César Sandino Pérez, Hernando Trujillo , et al. · 2023

Background and Aims Secondary atypical hemolytic uremic syndrome (secondary aHUS) is a heterogeneous group of thrombotic microangiopathies (TMA) associated with various underlying conditions. Unlike primary aHUS, there is still no hard evi…

#5785 ACUTE KIDNEY INJURY AS A RISK FACTOR FOR THE DEVELOPMENT OF CHRONIC KIDNEY DISEASE AND MORTALITY IN HOSPITALIZED PATIENTS Open

Julio Francisco Colina García, Lucía Cordero García-Galán, Marta Rivero Martínez, Paúl Hernández, Celia González-García , et al. · 2023

Background and Aims Acute kidney injury (AKI) is a complication that affects more than 5% of all hospital admissions and up to one third of patients admitted to critical care units. This entity, whose incidence is on the rise, remains a ma…

P266 Cryoablation with endocrine therapy for clinical stage I/II, ER+, HER2- invasive breast cancer in patients with omission of surgical axillary staging Open

J.M. Oliver Goldaracena, C. Martí Alvárez, V. Córdoba Chicote, José Ignacio Sánchez-Méndez, Margaret Navarro , et al. · 2023

contracture grade IV without postoperative radiotherapy.All capsular contracture grade III or IV required additional revision breast surgery. Conclusion(s):No significant difference in complication between ADM, non-ADM and TiLOOP implant-b…

P267 Percutaneous cryoablation treatment of early and low risk breast cancer. An effective alternative to surgical treatment Open

M.J. Roca Navarro, Y. Navarro Monforte, D. Garrido Alonso, Teresa Díaz de Bustamante Durbán, M.V. Córdoba Chicote , et al. · 2023

Why should genetic testing be incorporated into routine clinical practice in nephrology? The utility of specialized clinics. An emerging need Open

Eduardo Gutiérrez, Hernando Trujillo, L Aubert, Justo Sandino, Enrique Morales , et al. · 2023

Octogenarians with chronic kidney disease in the nephrology clinic: Progressors vs. non-progressors Open

Aida Frías, Francisco Vargas, Justo Sandino, Raquel Berzal, Marta Rivero , et al. · 2023

Background The current definition of chronic kidney disease applied to patients over the age of 80 has increased the number of referrals to Nephrology. However not all of these patients may benefit from its assessment. This study aims to a…

Efectos renales adversos por inhibidores del check-point (ICP) en pacientes con cáncer. Recomendaciones del grupo de Onconefrología de la Sociedad Española de Nefrología (SEN) Open

Fabiola Alonso, Ángel L.M. Martín de Francisco, Pilar Auñón, Clara García-Carro, Patricia García , et al. · 2022

¿Por qué se debe incorporar el estudio genético a la práctica clínica habitual en nefrología? La utilidad de consultas monográficas. Una necesidad emergente Open

Eduardo Gutiérrez, Hernando Trujillo, L Aubert, Justo Sandino, E. Hernández , et al. · 2022

Cardiac monitoring during trastuzumab therapy in metastatic breast cancer: early incidence of cardiac dysfunction Open

Francesco Perone, Pilar Auñón, Laura Rodríguez, D. Viñal, Juan Caro‐Codón , et al. · 2022

Trastuzumab therapy has dramatically changed breast cancer prognosis. Consensus documents recommend a close monitoring during therapy, not always feasible, especially in metastatic breast cancer. The purpose of this study is to describe tr…

MO195ATYPICAL HEMOLYTIC UREMIC SYNDROME IN LUNG TRANSPLANTATION: TREATMENT WITH ECULIZUMAB, OUR EXPERIENCE Open

Raquel Berzal Rico, Teresa Cavero, Pilar Auñón, Aida Frías González, L Aubert , et al. · 2021

Background and Aims Atypical haemolytic uremic syndrome (aHUS) is a clinical entity characterized by acute kidney injury, thrombocytopenia and microangiopathic hemolytic anemia. There are several cases of AHUS in non-renal solid organ tran…

POS-134 ECULIZUMAB IN ATYPICAL HEMOLYTIC UREMIC SYNDROME RELATED TO LUNG TRANSPLANT Open

Teresa Cavero, Raquel Berzal, Pilar Auñón, Hernando Trujillo, Manuel Praga · 2021

Atypical hemolytic uremic syndrome (aHUS) is a clinical entity characterized by acute kidney injury, thrombocytopenia and microangiopathic hemolytic anemia. aHUS related to lung transplant is well recognized. Kidney and patient survival ar…

Monographic consultation of onconephrology. Rationale and implementation Open

Fabiola Alonso, Pilar Auñón, Teresa Cavero, Mercedes Salgueira, Manuel Praga , et al. · 2021

The increase in demand for medical care for renal complications associated with neoplastic diseases is a reality in most nephrology departments. In response to this overall situation, the creation of healthcare models such as monographic c…

Consulta monográfica de onconefrología. Justificación y puesta en marcha Open

Fabiola Alonso, Pilar Auñón, Teresa Cavero, Mercedes Salgueira, Manuel Praga , et al. · 2020

Cardiovascular risk factors during cancer treatment: prevalence, incidence and prognostic relevance Open

Juan Caro Codón, Teresa López‐Fernández, Carlos Álvarez-Ortega, Pilar Auñón, Isabel Rodríguez Rodríguez , et al. · 2020

Background The actual usefulness of CV risk factor assessment in the prognostic evaluation of cancer patients treated with cardiotoxic treatment remains largely unknown. Design Prospective multicenter study in patients scheduled to receive…

Classification, prevalence, and outcomes of anticancer therapy-induced cardiotoxicity: the CARDIOTOX registry Open

José López‐Sendón, Carlos Álvarez-Ortega, Pilar Auñón, Antonio Buño Soto, Alexander R. Lyon , et al. · 2020

Aim Cardiotoxicity (CTox) is a major side effect of cancer therapies, but uniform diagnostic criteria to guide clinical and research practices are lacking. Methods and results We prospectively studied 865 patients, aged 54.7 ± 13.9; 16.3% …

Primary antiphospholipid syndrome presented as thrombotic microangiopathy in renal transplantation Open

Teresa Bada-Bosch, Beatríz Redondo, Ángel Sevillano, Hernando Trujillo, Pilar Auñón , et al. · 2020

Microangiopatía trombótica como recidiva de síndrome antifosfolípido en trasplante renal Open

Teresa Bada-Bosch, Beatríz Redondo, Ángel Sevillano, Marina Alonso, Hernando Trujillo , et al. · 2019

Pre-emptive rituximab in focal and segmental glomerulosclerosis patients at risk of recurrence after kidney transplantation Open

Pilar Auñón, Natalia Polanco, María José Pérez‐Sáez, Emilio Rodrigo, Asunción Sancho , et al. · 2019

Background The recurrence of proteinuria after kidney transplantation (KT) is a characteristic complication of focal segmental glomerulosclerosis (FSGS). It has been suggested that pre-emptive rituximab might prevent recurrences in patient…

FP748PREEMPTIVE RITUXIMAB IN FOCAL AND SEGMENTAL GLOMERULOSCLEROSIS PATIENTS AT RISK FOR RECURRENCE AFTER TRANSPLANTATION Open

Pilar Auñón, Natalia Polanco, María José Pérez, Emilio Rodrigo, Asunción Sancho , et al. · 2018

4.5 mg/kg.Sixty-eight percent of the population had delayed graft function (DGF) and 9.4%, primary nonfunction.We had 6 cases of acute rejection (50% humoral), with all but one successfully treated.The 6-month mean estimated glomerular fil…

SP167RECURRENCE OF MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS AFTER KIDNEY TRANSPLANTATION Open

Fernando Caravaca‐Fontán, Ángel Sevillano, Natalia Polanco, Ester González, Pilar Auñón , et al. · 2018

disease, but it also occurs (25% cases) as a secondary disease to other conditions.The histopathological findings do not allow a differentiation between primary or secondary forms.Most patients with idiopathic MGN have autoantibodies of Ig…

Micro-RNA profile in advanced metastatic breast cancer as a predictive tool for response to bevacizumab-paclitaxel Open

Marta Mendiola, Victoria Heredia-Soto, Jesús Herránz, R MARTIN, Pilar Auñón , et al. · 2017

Distribution of genomically defined recurrence risk in luminal A and B breast tumors defined by inmunohistochemistry: A retrospective study in Spanish population Open

Sara Ramírez, Marı́a del Monte-Millán, Sara López‐Tarruella, Iván Márquez‐Rodas, Yolanda Jerez , et al. · 2017

Defining the optimal sequence for the systemic treatment of metastatic breast cancer Open

Joan Albanell Mestres, A. B. iMolins, Lourdes Calvo, José Ignacio Chacón, Eva Ciruelos Gil , et al. · 2016

Reply to the comment “Infection with hepatitis C virus, interferon α and lupus: An odd association” Open

Pilar Auñón, Enrique Morales · 2015

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