Pingjun Chang
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View article: Genetic spectrum of congenital cataract with optional ocular and multisystem abnormalities
Genetic spectrum of congenital cataract with optional ocular and multisystem abnormalities Open
This study provided a comprehensive characterization of the diverse clinical phenotypes of CC in Chinese cohort and updates the mutational landscape of CC-associated genes. By employing WES, we expand the genetic spectrum and highlight add…
Modeling monocular form deprivation in rabbits using a simulated-cataract intraocular lens Open
AIM: To establish an animal model of form deprivation amblyopia based on a simulated cataract intraocular lens (IOLs). METHODS: Poly(dimethyl siloxane)-SiO2 thin films (PSF) with different degrees of opacity as IOL materials were prepared.…
Transcapsular scleral fixation of the standard capsular tension ring and in-the-bag intraocular lens implantation for severely subluxated lenses Open
AIM: To present a technique of transcapsular scleral fixation of the standard capsular tension ring (CTR) through equatorial capsulotomy and in-the-bag intraocular lens (IOL) implantation in subluxated lenses. METHODS: This retrospective c…
Intelligent Verification Tool for Surgical Information of Ophthalmic Patients: A Study Based on Artificial Intelligence Technology Open
Objective: With the development of day surgery, the characteristics of “short, frequent and fast” ophthalmic surgery are becoming more prominent. However, nurses are not efficient in verifying patients’ surgical information, and problems s…
TiO<sub>2</sub>-Nanoparticle–Enhanced Sonodynamic Therapy for Prevention of Posterior Capsular Opacification and Ferroptosis Exploration of Its Mechanism Open
TiO2-IOLs combined with SDT effectively prevented PCO by generating ROS and intracellular ferroptosis.
Accuracy of Modern Intraocular Lens Formulas in Highly Myopic Eyes Implanted With Plate‐Haptic Intraocular Lenses Open
In long eyes with plate-haptic IOLs, RBF 3.0 performed best, closely followed by Zhu-Lu, Olsen, and EVO 2.0; Karmona and Naeser 2 are discouraged for extreme AL and steep K conditions, respectively; Haigis-CMAL is not suggested for shallow…
Dynamic Changes of Capsular-Intraocular Lens Adhesion in Plate-Haptic Hydrophilic and Loop-Haptic Hydrophobic Eyes Open
The plate-haptic IOL demonstrated excellent capsular adhesion compared to the loop-haptic IOL, which was probably attributed to haptic compressibility. A special cocked configuration of the capsular bend in plate-haptic IOL was observed fo…
View article: Comparison of the effect of capsular bend on the rotational stability between 2 toric intraocular lenses
Comparison of the effect of capsular bend on the rotational stability between 2 toric intraocular lenses Open
Purpose: To compare the effect of capsular bend on the rotational stability between 2 toric intraocular lenses (IOLs). Setting: Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang Province, China. Design: Prospective study. Meth…
Unsupervised Learning Based on Meibography Enables Subtyping of Dry Eye Disease and Reveals Ocular Surface Features Open
In this study, we developed an unsupervised neural network model to cluster patients with dry eye into image-based subtypes using meibography images. We annotated these subtypes with functional and morphological clinical characteristics.
Morphological changes in the meibomian gland in children with tic disorders Open
Blinking disorders have a significant impact on MG morphology. In children with tic disorders, more attention should be devoted to monitoring the MG over time.
View article: Evaluation of optic nerve head vessels density changes after phacoemulsification cataract surgery using optical coherence tomography angiography
Evaluation of optic nerve head vessels density changes after phacoemulsification cataract surgery using optical coherence tomography angiography Open
AIM: To evaluate optic nerve head (ONH) vessel density (VD) changes after cataract surgery using optical coherence tomography angiography (OCTA). METHODS: This was a prospective observational study. Thirty-four eyes with mild/moderate cata…
Treatment of visual axis opacification and secondary membranes with Nd:YAG laser after pediatric cataract surgery under intranasal sedation Open
Purpose To describe neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser treatment of visual axis opacification and secondary membranes in pediatric patients with cataracts under intranasal dexmedetomidine sedation. Methods Twenty eyes o…
Efficacy of Toric Intraocular Lens Implantation in Patients Older Than 80 Years with Cataracts and Corneal Astigmatism Open
The results demonstrate the efficacy of toric IOL implantation in patients older than 80 years with corneal astigmatism and provide strong evidence for cataract surgeons to encourage such patients to choose toric IOLs.
Femtosecond Laser-Assisted Cataract Surgery versus Conventional Phacoemulsification Surgery: Clinical Outcomes with EDOF IOLs Open
In this study, we evaluate and compare the outcomes of conventional phacoemulsification cataract surgery (CPS) and femtosecond laser-assisted cataract surgery (FLACS) with the implantation of an extended depth of field (EDOF) intraocular l…
Capsulotomy opening diameter outcomes in aphakic eyes after primary congenital cataract removal and its association Open
Aim To observe the change of capsulotomy opening diameter (COD) in aphakic eyes after primary congenital cataract removal and investigate its influencing factors. Methods Ocular parameters, including corneal diameter (CD), axial length (AL…
Posterior Capsular Outcomes of Pediatric Cataract Surgery With In-The-Bag Intraocular Lens Implantation Open
Aim To investigate the change of posterior capsular outcomes of pediatric cataract surgery with primary in-the-bag intraocular lens (IOL) implantation. Methods We conducted a case series of pediatric cataract children who underwent catarac…
A Retrospective Study on the Eye-Related Quality of Life, Functional Vision, and Their Determinants Among Children Following Congenital and Developmental Cataracts Surgery and Its Impact on Their Families Using the PedEyeQ Open
Objectives To evaluate the eye-related quality of life (ER-QOL), functional vision, and their determinants in children following congenital and developmental cataract surgery, as the impact on their families, using the Pediatric Eye Questi…
Meibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye Study Open
Purpose: To evaluate the morphology changes of meibomian glands (MGs) after cataract surgery. Setting: Hangzhou Branch of the Eye Hospital of Wenzhou Medical University, Zhejiang, China. Methods: In this contra-lateral eye study, 40 patien…
The Relationship Between Age and the Morphology of the Crystalline Lens, Ciliary Muscle, Trabecular Meshwork, and Schlemm’s Canal: An in vivo Swept-Source Optical Coherence Tomography Study Open
Purpose: To evaluate the effects of age on the morphologies of the crystalline lens, ciliary muscle (CM), Schlemm’s canal (SC), and trabecular meshwork (TM) using swept-source optical coherence tomography (SS-OCT). Methods: Images of the c…
Assessment of anterior chamber angle changes after phacoemulsification with swept-source OCT Open
AIM: To assess the changes of anterior chamber angle in patients with shallow anterior chamber after phacoemulsification combined with intraocular lens (IOL) implantation, based on anterior segment swept-source optical coherence tomography…
Comparison of Aphakic Refraction and Biometry-Based Formulae for Secondary In-The-Bag and Sulcus-Implanted Intraocular Lens Power Estimation in Children Open
Purpose: The aim of the study was to compare the accuracy of refractive outcomes in children undergoing secondary in-the-bag or cilliary sulcus intraocular lens (IOL) implantation, using aphakic refraction (AR)-based formulae (Hug and Khan…
Comparison of the Accuracy of IOL Power Calculation Formulas for Pediatric Eyes in Children of Different Ages Open
Purpose . This study aims to compare the accuracy of five intraocular lens (IOL) power calculation formulas (SRK/T, Hoffer Q, Holladay 1, Haigis, and Holladay 2) for pediatric eyes in children of different ages. Methods . In this prospecti…