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View article: Engineered pattern recognition receptors enhance broad-spectrum plant resistance
Engineered pattern recognition receptors enhance broad-spectrum plant resistance Open
Conventional plant resistance breeding has primarily focused on intracellular immune receptors, while cell-surface pattern recognition receptors (PRRs) have been underexplored because of their comparatively modest contributions to resistan…
View article: Cell-type-specific execution of effector-triggered immunity
Cell-type-specific execution of effector-triggered immunity Open
Summary Effector-triggered immunity (ETI) is a central component of host defense, but whether all cell types execute ETI similarly remains unknown. We combined chemically imposed immune activation with single-cell transcriptomics to profil…
View article: Modular mechanisms of immune priming and growth inhibition mediated by plant effector-triggered immunity
Modular mechanisms of immune priming and growth inhibition mediated by plant effector-triggered immunity Open
Excessive activation of effector-triggered immunity (ETI) in plants inhibits plant growth and activates cell death. ETI mediated by intracellular Toll/interleukin-1 receptor/resistance protein (TIR) nucleotide-binding, leucine-rich repeat …
View article: Enhancing plant broad-spectrum resistance through engineered pattern recognition receptors
Enhancing plant broad-spectrum resistance through engineered pattern recognition receptors Open
Conventional plant resistance breeding has primarily focused on intracellular immune receptors, while cell-surface pattern recognition receptors (PRRs) have been underexplored due to their comparatively modest contributions to resistance. …
View article: Spatiotemporal transcriptional networks control the plasticity of chickpea root exodermis
Spatiotemporal transcriptional networks control the plasticity of chickpea root exodermis Open
Abscisic acid (ABA) regulates plant responses to stress and influences the differentiation of root barrier cell types, such as the endodermis and exodermis. Despite the importance of the exodermis in limiting water and solute fluxes, its r…
View article: Modular mechanisms of immune priming and growth inhibition mediated by plant effector-triggered immunity
Modular mechanisms of immune priming and growth inhibition mediated by plant effector-triggered immunity Open
Summary Excessive activation of effector-triggered immunity (ETI) in plants inhibits plant growth and activates cell death. ETI mediated by intracellular Toll/Interleukin-1 receptor/Resistance protein (TIR) nucleotide-binding leucine-rich-…
View article: Vision, challenges and opportunities for a Plant Cell Atlas
Vision, challenges and opportunities for a Plant Cell Atlas Open
Note: for full list of Plant Cell Atlas Consortium, see publication (p17). With growing populations and pressing environmental problems, future economies will be increasingly plant-based. Now is the time to reimagine plant science as a cri…
View article: Cell-type-specific responses to fungal infection in plants revealed by single-cell transcriptomics
Cell-type-specific responses to fungal infection in plants revealed by single-cell transcriptomics Open
Pathogen infection is a dynamic process. Here, we employ single-cell transcriptomics to investigate plant response heterogeneity. By generating an Arabidopsis thaliana leaf atlas encompassing 95,040 cells during infection by a fungal patho…
View article: Seed Longevity is Controlled by Metacaspases
Seed Longevity is Controlled by Metacaspases Open
To survive extreme desiccation, seeds enter a period of dormancy that can last millennia. Seed dormancy involves the accumulation of protective storage proteins through unknown adjustments in proteasomal degradation. Mutating all six type …
View article: Cell type-specific responses to fungal infection in plants revealed by single-cell transcriptomics
Cell type-specific responses to fungal infection in plants revealed by single-cell transcriptomics Open
Summary Plant infection by microbial pathogens is a dynamic process. Here, we investigated the heterogeneity of plant responses in the context of pathogen location. A single-cell atlas of Arabidopsis thaliana leaves challenged by the fungu…
View article: Seed Longevity is Controlled by Metacaspases
Seed Longevity is Controlled by Metacaspases Open
To survive extreme desiccation, seeds enter dormancy that can last millennia. This dormancy involves the accumulation of protective but structurally disordered storage proteins through unknown adjustments of proteolytic surveillance mechan…
View article: Bjerrum Schafer-Nielsen buffer, modified by DING LAB, v1.0 v1
Bjerrum Schafer-Nielsen buffer, modified by DING LAB, v1.0 v1 Open
This is a modified transfer buffer recipe for a semi-dry Western blot.
View article: Transcriptional regulation of plant innate immunity
Transcriptional regulation of plant innate immunity Open
Transcriptional reprogramming is an integral part of plant immunity. Tight regulation of the immune transcriptome is essential for a proper response of plants to different types of pathogens. Consequently, transcriptional regulators are pr…
View article: Thirty years of resistance: Zig-zag through the plant immune system
Thirty years of resistance: Zig-zag through the plant immune system Open
Understanding the plant immune system is crucial for using genetics to protect crops from diseases. Plants resist pathogens via a two-tiered innate immune detection-and-response system. The first plant Resistance (R) gene was cloned in 199…
View article: Perception of structurally distinct effectors by the integrated WRKY domain of a plant immune receptor
Perception of structurally distinct effectors by the integrated WRKY domain of a plant immune receptor Open
Plants use intracellular nucleotide-binding domain (NBD) and leucine-rich repeat (LRR)–containing immune receptors (NLRs) to detect pathogen-derived effector proteins. The Arabidopsis NLR pair RRS1-R/RPS4 confers disease resistance to diff…
View article: Chromatin accessibility landscapes activated by cell-surface and intracellular immune receptors
Chromatin accessibility landscapes activated by cell-surface and intracellular immune receptors Open
Activation of cell-surface and intracellular receptor-mediated immunity results in rapid transcriptional reprogramming that underpins disease resistance. However, the mechanisms by which co-activation of both immune systems lead to transcr…
View article: Perception of structurally distinct effectors by the integrated WRKY domain of a plant immune receptor
Perception of structurally distinct effectors by the integrated WRKY domain of a plant immune receptor Open
Plants use intracellular immune receptors (NLRs) to detect pathogen-derived effector proteins. The Arabidopsis NLR pair RRS1-R/RPS4 confers disease resistance to different bacterial pathogens by perceiving structurally distinct effectors A…
View article: A Comparative Overview of the Intracellular Guardians of Plants and Animals: NLRs in Innate Immunity and Beyond
A Comparative Overview of the Intracellular Guardians of Plants and Animals: NLRs in Innate Immunity and Beyond Open
Nucleotide-binding domain leucine-rich repeat receptors (NLRs) play important roles in the innate immune systems of both plants and animals. Recent breakthroughs in NLR biochemistry and biophysics have revolutionized our understanding of h…
View article: Induced proximity of a TIR signaling domain on a plant-mammalian NLR chimera activates defense in plants
Induced proximity of a TIR signaling domain on a plant-mammalian NLR chimera activates defense in plants Open
Significance Animal NLRs form wheel-like structures called inflammasomes upon perception of pathogen-associated molecules. The induced proximity of the signaling domains at the center of the wheel is hypothesized to recruit caspases for th…
View article: Chromatin accessibility landscapes activated by cell surface and intracellular immune receptors
Chromatin accessibility landscapes activated by cell surface and intracellular immune receptors Open
Activation of cell Surface and Intracellular Receptor-Mediated Immunity (SRMI and IRMI) results in rapid transcriptional reprogramming that underpins disease resistance. However, the mechanisms by which SRMI and IRMI lead to transcriptiona…
View article: Plant_Innate_Immunity_ATAC-seq
Plant_Innate_Immunity_ATAC-seq Open
Chromatin accessibility landscapes activated by cell surface and intracellular immune receptors Ding et al 2020 This repository stored all input dataset & output dataset except bam files. To make bam files, raw read data are stored in acce…
View article: Plant_Innate_Immunity_ATAC-seq
Plant_Innate_Immunity_ATAC-seq Open
Chromatin accessibility landscapes activated by cell surface and intracellular immune receptors Ding et al 2020 This repository stored all input dataset & output dataset except bam files. To make bam files, raw read data are stored in acce…
View article: Mutual Potentiation of Plant Immunity by Cell-surface and Intracellular Receptors
Mutual Potentiation of Plant Immunity by Cell-surface and Intracellular Receptors Open
The plant immune system involves cell-surface receptors that detect intercellular pathogen-derived molecules, and intracellular receptors that activate immunity upon detection of pathogen-secreted effectors that act inside the plant cell. …
View article: Estradiol-inducible AvrRps4 expression reveals distinct properties of TIR-NLR-mediated effector-triggered immunity
Estradiol-inducible AvrRps4 expression reveals distinct properties of TIR-NLR-mediated effector-triggered immunity Open
Plant nucleotide-binding domain, leucine-rich repeat receptor (NLR) proteins play important roles in recognition of pathogen-derived effectors. However, the mechanism by which plant NLRs activate immunity is still largely unknown. The pair…