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View article: Diverse Impact of E-Cigarette Aerosols on Oxidative Stress and Inflammation in Lung Alveolar Epithelial Cells (A549)
Diverse Impact of E-Cigarette Aerosols on Oxidative Stress and Inflammation in Lung Alveolar Epithelial Cells (A549) Open
This study investigated the pro-inflammatory and pro-oxidative effects of popular electronic cigarette aerosols (ECAs) compared with conventional cigarette smoke (CS) in the cultured human alveolar epithelial cell line (A549). Using cytoto…
View article: Impact of E-Cigarette Aerosols on Oxidative Stress and Inflammation in Lung Alveolar Epithelial Cells (A549): The Role of Subclinical Inflammation
Impact of E-Cigarette Aerosols on Oxidative Stress and Inflammation in Lung Alveolar Epithelial Cells (A549): The Role of Subclinical Inflammation Open
This study investigated the proinflammatory and prooxidative effects of popular electronic cigarette (EC) aerosols compared with conventional cigarette smoke (CS) in cultured human alveolar epithelial cell line (A549). Using cytotoxicity a…
View article: Signalling Pathways of Inflammation and Cancer in Human Mononuclear Cells: Effect of Nanoparticle Air Pollutants
Signalling Pathways of Inflammation and Cancer in Human Mononuclear Cells: Effect of Nanoparticle Air Pollutants Open
Fine inhalable particulate matter (PM) triggers an inflammatory response in the airways and activates mononuclear cells, mediators of tissue homeostasis, and tumour-promoting inflammation. We have assessed ex vivo responses of human monocy…
View article: New agents modulating the renin-angiotensin-aldosterone system—Will there be a new therapeutic option?
New agents modulating the renin-angiotensin-aldosterone system—Will there be a new therapeutic option? Open
The renin-angiotensin-aldosterone system (RAAS) is more complex than it was originally regarded. According to the current subject knowledge, there are two main axes of the RAAS: (1) angiotensin-converting enzyme (ACE)-angiotensin II-AT 1 r…
View article: Zakres odpowiedzialności farmaceuty w terapii przy użyciu leków biopodobnych — uregulowania prawne EMA
Zakres odpowiedzialności farmaceuty w terapii przy użyciu leków biopodobnych — uregulowania prawne EMA Open
Leki biologiczne to bialka, polipeptydy i glikoproteiny rozniące sie miedzy sobą strukturą przestrzenną. Wytworzenie lekow biologicznych stanowi zlozony cykl produkcyjny, trudny do odtworzenia, a obecnie dostepne metody analityczne nie poz…