Piyush B. Gupta
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View article: An intricate case of fulminant necrotising infection of perineum - from destruction to restoration: a case report
An intricate case of fulminant necrotising infection of perineum - from destruction to restoration: a case report Open
Necrotising fasciitis (NF) is a well-known fulminant and disabling soft tissue infection. it can affect any age group, gender and healthy individuals. The toxicity and sepsis that it is capable of inciting is immense and caries high mortal…
View article: Evaluation of serum cholesterol levels as risk factors for developing surgical site infection following elective surgery
Evaluation of serum cholesterol levels as risk factors for developing surgical site infection following elective surgery Open
Background: Surgical site infections (SSIs) occur within 30 days of surgery or within one year if a prosthesis is implanted. They are classified as superficial, deep, or organ-space infections. Factors such as wound class, blood transfusio…
View article: DDR1 regulates RUNX1-CBFβ to control breast stem cell differentiation
DDR1 regulates RUNX1-CBFβ to control breast stem cell differentiation Open
View article: Inferior epigastric artery aneurysm: a rarest complication of laparoscopic cholecystectomy
Inferior epigastric artery aneurysm: a rarest complication of laparoscopic cholecystectomy Open
Case is an uncommon rare incidental finding of an inferior epigastric artery aneurysm (IEAA) following a routine laparoscopic cholecystectomy performed for symptomatic gallstones. The vascular anomaly with idiopathic thrombocytopenic purpu…
View article: Analytical Validation of NavDx+Gyn, a cfDNA-Based Fragmentomic Profiling Assay for HPV-Driven Gynecologic Cancers
Analytical Validation of NavDx+Gyn, a cfDNA-Based Fragmentomic Profiling Assay for HPV-Driven Gynecologic Cancers Open
Background/Objectives: The NavDx+Gyn blood test detects and quantifies fourteen HPV types in various sample types to provide a reliable means of detecting and monitoring HPV-driven gynecologic cancers. NavDx+Gyn is an extension of the NavD…
View article: Personalized Immunosuppressive Strategies in Intestinal Transplantation: A Predictive Model for Graft Survival and Patient Outcomes
Personalized Immunosuppressive Strategies in Intestinal Transplantation: A Predictive Model for Graft Survival and Patient Outcomes Open
View article: Multivisceral Re-Transplantation with En Bloc Horseshoe Kidney and Bladder in a Pediatric Recipient: Video Presentation and Literature Review
Multivisceral Re-Transplantation with En Bloc Horseshoe Kidney and Bladder in a Pediatric Recipient: Video Presentation and Literature Review Open
View article: Supplementary Figure S1 from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance
Supplementary Figure S1 from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance Open
Supplementary Figure S1: Case examples of false negative TTMV-HPV DNA results identified during surveillance
View article: Supplementary Figure S1 from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance
Supplementary Figure S1 from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance Open
Supplementary Figure S1: Case examples of false negative TTMV-HPV DNA results identified during surveillance
View article: Data from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance
Data from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance Open
Background: Human papillomavirus (HPV) is causally linked to oropharyngeal squamous cell carcinoma (OPSCC). Consensus guidelines recommend clinical exams and imaging in decreasing frequency as part of post-treatment surveillance for recurr…
View article: Targeting and monitoring ovarian cancer invasion with an RNAi and peptide delivery system
Targeting and monitoring ovarian cancer invasion with an RNAi and peptide delivery system Open
RNA interference (RNAi) therapeutics are an emerging class of medicines that selectively target mRNA transcripts to silence protein production and combat disease. Despite the recent progress, a generalizable approach for monitoring the eff…
View article: Supplementary Figure S1 from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance
Supplementary Figure S1 from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance Open
Supplementary Figure S1: Case examples of false negative TTMV-HPV DNA results identified during surveillance
View article: Supplementary Figure S1 from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance
Supplementary Figure S1 from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance Open
Supplementary Figure S1: Case examples of false negative TTMV-HPV DNA results identified during surveillance
View article: Data from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance
Data from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance Open
Purpose:Human papillomavirus (HPV) is causally linked to oropharyngeal squamous cell carcinoma (OPSCC). Consensus guidelines recommend clinical exams and imaging in decreasing frequency as part of posttreatment surveillance for recurrence.…
View article: Data from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance
Data from Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance Open
Purpose:Human papillomavirus (HPV) is causally linked to oropharyngeal squamous cell carcinoma (OPSCC). Consensus guidelines recommend clinical exams and imaging in decreasing frequency as part of posttreatment surveillance for recurrence.…
View article: Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance
Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance Open
Purpose: Human papillomavirus (HPV) is causally linked to oropharyngeal squamous cell carcinoma (OPSCC). Consensus guidelines recommend clinical exams and imaging in decreasing frequency as part of posttreatment surveillance for recurrence…
View article: Supplementary Tables from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress
Supplementary Tables from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress Open
PDF file 59K, Table S1: GSEA of microarray data from Cmp302-treated cells; Table S2: ECM gene expression in luminal and basal-B breast cancer lines
View article: Data from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress
Data from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress Open
Epithelial-to-mesenchymal transition (EMT) promotes both tumor progression and drug resistance, yet few vulnerabilities of this state have been identified. Using selective small molecules as cellular probes, we show that induction of EMT g…
View article: Supplementary Materials from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress
Supplementary Materials from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress Open
PDF file 99K, Supplementary figure and table legends
View article: Data from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress
Data from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress Open
Epithelial-to-mesenchymal transition (EMT) promotes both tumor progression and drug resistance, yet few vulnerabilities of this state have been identified. Using selective small molecules as cellular probes, we show that induction of EMT g…
View article: Supplementary Figures from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress
Supplementary Figures from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress Open
Supplementary Figures PDF file 390K, Fig. S1: Validation of EMT-selective small molecules; Fig. S2: EMT increases sensitivity to ER stressors; Fig. S3: Cells that undergo an EMT are highly secretory; Fig. S4: Inhibition of ECM genes abroga…
View article: Supplementary Tables from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress
Supplementary Tables from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress Open
PDF file 59K, Table S1: GSEA of microarray data from Cmp302-treated cells; Table S2: ECM gene expression in luminal and basal-B breast cancer lines
View article: Supplementary Materials from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress
Supplementary Materials from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress Open
PDF file 99K, Supplementary figure and table legends
View article: Supplementary Figures from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress
Supplementary Figures from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress Open
Supplementary Figures PDF file 390K, Fig. S1: Validation of EMT-selective small molecules; Fig. S2: EMT increases sensitivity to ER stressors; Fig. S3: Cells that undergo an EMT are highly secretory; Fig. S4: Inhibition of ECM genes abroga…
View article: Supplementary Figure 3 from Systemic Stromal Effects of Estrogen Promote the Growth of Estrogen Receptor–Negative Cancers
Supplementary Figure 3 from Systemic Stromal Effects of Estrogen Promote the Growth of Estrogen Receptor–Negative Cancers Open
Supplementary Figure 3 from Systemic Stromal Effects of Estrogen Promote the Growth of Estrogen Receptor–Negative Cancers
View article: Supplementary Figure 3 from Systemic Stromal Effects of Estrogen Promote the Growth of Estrogen Receptor–Negative Cancers
Supplementary Figure 3 from Systemic Stromal Effects of Estrogen Promote the Growth of Estrogen Receptor–Negative Cancers Open
Supplementary Figure 3 from Systemic Stromal Effects of Estrogen Promote the Growth of Estrogen Receptor–Negative Cancers
View article: Supplementary Table 4 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
Supplementary Table 4 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways Open
Supplementary Table 4 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
View article: Supplementary Figures 1-6 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
Supplementary Figures 1-6 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways Open
Supplementary Figures 1-6 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
View article: Supplementary Figure Legends 1-6 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
Supplementary Figure Legends 1-6 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways Open
Supplementary Figure Legends 1-6 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
View article: Supplementary Table 3 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
Supplementary Table 3 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways Open
Supplementary Table 3 from Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways