Polina Obukhova
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View article: Immune Antibodies Recognizing the Stem Region of SARS-CoV-2 Spike Protein: Molecular Modelling and <i>In Vitro</i> Study of Synthetic Peptides Presentation to the Antibodies
Immune Antibodies Recognizing the Stem Region of SARS-CoV-2 Spike Protein: Molecular Modelling and <i>In Vitro</i> Study of Synthetic Peptides Presentation to the Antibodies Open
Antibodies to peptide 1147 (amino acids 1147-61) of the SARS-CoV-2 protein S are highly diagnostic. Peptide 1147, although located in a region that is partly spatially hidden in the intact protein, is not subject to mutations, suggesting t…
View article: Some Human Anti-Glycan Antibodies Lack the Ability to Activate the Complement System
Some Human Anti-Glycan Antibodies Lack the Ability to Activate the Complement System Open
Background. Naturally occurring human antibodies against glycans recognize and quickly eliminate infectious bacteria, viruses and aberrantly glycosylated neoplastic malignant cells, and they often initiate processes that involve the comple…
View article: Antibodies Against Unusual Forms of Sialylated Glycans
Antibodies Against Unusual Forms of Sialylated Glycans Open
Previous studies have shown that in the blood of healthy donors (1) there are no natural antibodies against sialylated glycoproteins, which contain Neu5Ac (N-acetylneuraminic acid) as the most widespread form of human sialic acid, and (2) …
View article: AB0-incompatibility of mother and fetus: the role of anti-glycan alloantibodies in the hemolytic disease of newborns
AB0-incompatibility of mother and fetus: the role of anti-glycan alloantibodies in the hemolytic disease of newborns Open
The mother and fetus incompatibility due to Rh-factor, blood group or other blood factors can lead to hemolytic disease of the fetus and newborn (HDN). HDN is a clinical disease condition of the fetus and newborn as a result of hemolysis, …
View article: Human Natural Antibodies Recognizing Glycan Galβ1-3GlcNAc (LeC)
Human Natural Antibodies Recognizing Glycan Galβ1-3GlcNAc (LeC) Open
The level of human natural antibodies of immunoglobulin M isotype against LeC in patients with breast cancer is lower than in healthy women. The epitope specificity of these antibodies has been characterized using a printed glycan array an…
View article: Corrigendum to: Are there specific antibodies against Neu5Gc epitopes in the blood of healthy individuals?
Corrigendum to: Are there specific antibodies against Neu5Gc epitopes in the blood of healthy individuals? Open