Explanipedia

What does "housebound" mean? Mixed methods study to develop a consensus definition Open

Polly Duncan, Nathan Yung, Shoba Dawson, Laura D Howe, Ailsa Cameron , et al. · 2025

Background Housebound patients are an under-researched group who face challenges accessing primary healthcare and have complex needs. There is no consensus definition of housebound, hindering research. Aim To develop a definition of houseb…

The hidden workload study protocol: a national mixed-methods analysis of general practice workload and local demographics Open

K C Lee, Selma Audi, Thomas Brain, Polly Duncan, Serge Engamba , et al. · 2025

Background General practice workload is increasing. Routinely reported NHS data describes workload in relation to numbers of appointments and clinicians delivering appointments. However, “hidden” aspects of general practice workload, such …

Delivering relational continuity of care in light of recent GP contract changes Open

Molly Dineen, Serge Engamba, Nada Khan, Kate Sidaway‐Lee, Polly Duncan , et al. · 2025

Development and validation of a Japanese version of the multimorbidity treatment burden questionnaire Open

Takuya Aoki, Tadao Okada, Shoichi Masumoto, Ryota Takahashi, Yusuke Kanakubo , et al. · 2025

This study aimed to develop a Japanese version of the Multimorbidity Treatment Burden Questionnaire (J-MTBQ) and examine its validity and reliability. The MTBQ was translated into Japanese using forward and backward translation and cogniti…

Translation, Cultural Adaptation, and Validation of the Korean Version of the Multimorbidity Treatment Burden Questionnaire Open

Jihyang Lee, Da-In Park, Polly Duncan, Kyoung Suk Lee · 2025

Background Patients with hypertension and comorbidities face greater difficulties in managing their diseases than patients without comorbidities. Treatment burden is defined as individuals’ effort to manage their health and the impact it h…

Estimating the burden of vaccine-preventable lower respiratory tract disease in UK primary care: protocol for a prospective surveillance study (AvonCAP GP2) Open

Polly Duncan, Ruth Mears, Elizabeth Begier, Sanaz Rouhbakhsh Halvaei, Jo Southern , et al. · 2024

Background The true burden of acute lower respiratory tract disease (aLRTD; includes acute lower respiratory tract infection [aLRTI] and presumed non-infective exacerbations of chronic lung disease and heart failure) among adults presentin…

Patient safety in actioning and communicating blood test results in primary care: a UK wide audit using the Primary care Academic CollaboraTive (PACT) Open

Jessica Watson, Polly Duncan, Alex Burrell, Ian Bennett-Britton, Sam Hodgson , et al. · 2024

Background Errors associated with failures in filing, actioning and communicating blood test results can lead to delayed and missed diagnoses and patient harm. This study aimed to audit how blood tests in primary care are filed, actioned a…

Further development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ) Open

Polly Duncan, Lauren J Scott, Shoba Dawson, Muzrif Munas, Yvette Pyne , et al. · 2024

Objectives To undertake further psychometric testing of the Multimorbidity Treatment Burden Questionnaire (MTBQ) and examine whether reversing the scale reduced floor effects. Design Survey. Setting UK primary care. Participants Adults (≥1…

Validation of the Lithuanian multimorbidity treatment burden questionnaire (MTBQ) and its association with primary care patient characteristics Open

Olga Vasiliauskienė, Dovydas Vasiliauskas, Polly Duncan, Aušrinė Kontrimienė, Lina Jaruševičienė , et al. · 2023

The study's findings show that the MTBQ is applicable in assessing the treatment burden of multimorbid patients in Lithuania. Furthermore, the study demonstrates that Lithuanian patients with multimorbidity have average treatment burden sc…

Measurement of treatment burden in patients with multimorbidity in the Netherlands: translation and validation of the Multimorbidity Treatment Burden Questionnaire (NL-MTBQ) Open

L Engels, Tiny Van Merode, Monique Heijmans, Juliane Menting, Polly Duncan , et al. · 2023

Background Multimorbidity is a growing problem. The number and complexity of (non-)pharmaceutical treatments create a great burden for patients. Treatment burden refers to the perception of the weight of these treatments, and is associated…

Exploration of reasons for primary care testing (the Why Test study): a UK-wide audit using the Primary care Academic CollaboraTive Open

Jessica Watson, Alex Burrell, Polly Duncan, Ian Bennett-Britton, Sam Hodgson , et al. · 2023

Background Rates of blood testing have increased over the past two decades. Reasons for testing cannot easily be extracted from electronic health record databases. Aim To explore who requests blood tests and why, and what the outcomes of t…

Using the Primary care Academic CollaboraTive to explore the characteristics and healthcare use of older housebound patients in England: protocol for a retrospective observational study and clinician survey (the CHiP study) Open

Elizabeth Winn, Madeleine Kissane, Samuel William David Merriel, Thomas Brain, Victoria Silverwood , et al. · 2023

Background Older housebound people are an under-researched group for whom achieving good primary health care can be resource intensive. Aims To describe the characteristics and healthcare use of older (≥65 years) housebound people; explore…

Treatment burden in multiple long-term conditions: a mixed-methods study protocol Open

Rachel Johnson, Anastasiia G. Kovalenko, Thomas Blakeman, Maria Panagioti, Michael Lawton , et al. · 2023

Background Treatment burden represents the work patients undertake because of their health care, and the impact of that effort on the patient. Most research has focused on older adults (aged >65 years) with multiple long-term conditions (m…

Patient perceptions and experiences of medication review: qualitative study in general practice Open

Deborah McCahon, Polly Duncan, Rupert Payne, Jeremy Horwood · 2022

Treatment burden and associated factors: a population-based survey in Central Denmark Region 2017 Open

MH Pedersen, Polly Duncan, Mathias Lasgaard, Karina Friis, Chris Salisbury , et al. · 2022

Background Exploring treatment burden at a population level can provide evidence of the types of patients who need special attention and support. We aimed to determine factors associated with high perceived treatment burden in a population…

Treatment burden for older people with multimorbidity: a cross-sectional study in China Open

Liyuan Dou, Qiuling Jiang, Polly Duncan, Xiaoping Li · 2022

Background There has been little research in China about treatment burden. Studies internationally have found high treatment burden is associated with number of long-term conditions, low quality of life (QoL) iand poor medication adherence…

Treatment burden for older people with multimorbidity: a cross-sectional study in China Open

Liyuan Dou, Qiuling Jiang, Polly Duncan, Xiaoping Li · 2022

Background: There has been little research in China about treatment burden. Studies internationally have found high treatment burden is associated with number of long-term conditions, low quality of life (QoL) iand poor medication adherenc…

Adaptation and validation of a German version of the Multimorbidity Treatment Burden Questionnaire Open

Josefine Schulze, Amanda Breckner, Polly Duncan, Martin Scherer, Nadine Janis Pohontsch , et al. · 2022

Multimorbidity Treatment Burden Questionnaire (MTBQ): Translation, Cultural Adaptation, and Validation in French-Canadian Open

Line Guénette, Véronique Turcotte, Laurianne Bélanger, Lucie Blais, Caroline Sirois , et al. · 2022

Reliable treatment burden measures are needed given the aging population and the associated increase in multimorbidity and polypharmacy. Treatment burden is defined as the effort to care for one’s health and the resulting impact on one’s d…

Why Test study protocol: a UK-wide audit using the Primary Care Academic CollaboraTive (PACT) to explore the reasons for primary care testing Open

Alex Burrell, Polly Duncan, Ian Bennett-Britton, Sam Hodgson, Samuel William David Merriel , et al. · 2022

Background The number of blood tests done in primary care has been increasing over the past 20 years. Some estimates suggest that up to one-quarter of these tests may not have been needed. This could lead to a cascade effect of further inv…

Development of a model of medication review for use in clinical practice: Bristol medication review model Open

Deborah McCahon, Rachel Denholm, Alyson Huntley, Shoba Dawson, Polly Duncan , et al. · 2021

A multi-stakeholder approach to the co-production of the research agenda for medicines optimisation Open

John Fellenor, Nicky Britten, Molly Courtenay, Rupert Payne, José M Valderas , et al. · 2021

Treatment burden for patients with multimorbidity: cross-sectional study with exploration of a single-item measure Open

James Morris, Paul Roderick, Scott Harris, Guiqing Yao, Sam Crowe , et al. · 2020

Background Treatment burden is the effort required of patients to look after their health, and the impact this has on their wellbeing. Quantitative data on treatment burden for patients with multimorbidity are sparse, and no single-item tr…

A multi-stakeholder approach to the co-production of the research agenda for medicines optimisation Open

John Fellenor, Nicky Britten, Molly Courtenay, Rupert Payne, José M Valderas , et al. · 2020

Background Up to 50% of medicines are not used as intended, resulting in poor health and economic outcomes. Medicines optimisation is ‘a person-centred approach to safe and effective medicines use, to ensure people obtain the best possible…

A multi-stakeholder approach to the co-production of the research agenda for medicines optimisation Open

John Fellenor, Nicky Britten, Molly Courtenay, Rupert Payne, José M Valderas , et al. · 2020

Background Up to 50% of medicines are not used as intended, resulting in poor health and economic outcomes. Medicines optimisation is ‘a person-centred approach to safe and effective medicines use, to ensure people obtain the best possible…

A new collaborative model of primary care research: could it provide trainees and clinicians with more opportunities to get involved? Open

Polly Duncan, Rupert Payne, Samuel William David Merriel · 2020

Currently, primary care based trainees and clinicians can apply for research fellowships, with funded time to spend on research, but these are highly competitive and available only to the lucky few. In hospital specialties, networks of tra…

Translation, cultural adaptation and validation of the Chinese Multimorbidity Treatment Burden Questionnaire(C-MTBQ): a study of older hospital patients Open

Liyuan Dou, Juan Huang, Polly Duncan, Lixiang Guo · 2020

Background Due to an ageing population, multimorbidity is becoming more common. Treatment burden (the effort required of patients to look after their health and the impact this has on their wellbeing) is prevalent in patients with multimor…

The Impact of Digital-First Consultations on Workload in General Practice: Modeling Study Open

Chris Salisbury, Mairead Murphy, Polly Duncan · 2020

Background Health services in many countries are promoting digital-first models of access to general practice based on offering online, video, or telephone consultations before a face-to-face consultation. It is claimed that this will impr…

International prescribing patterns and polypharmacy in older people with advanced chronic kidney disease: results from the European Quality study Open

Samantha Hayward, Barnaby Hole, Rachel Denholm, Polly Duncan, James Morris , et al. · 2020

Background People with chronic kidney disease (CKD) are at high risk of polypharmacy. However, no previous study has investigated international prescribing patterns in this group. This article aims to examine prescribing and polypharmacy p…

Barriers and enablers to collaborative working between GPs and pharmacists: a qualitative interview study Open

Polly Duncan, Matthew J Ridd, Deborah McCahon, Bruce Guthrie, Christie Cabral · 2020

Background Many UK GP practices now employ a practice pharmacist, but little is known about how GPs and pharmacists work together to optimise medications for complex patients with multimorbidity. Aim To explore GP and pharmacist perspectiv…

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