Wing P. Chan
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View article: Towards a unified approach: Standardising radiological diagnosis and grading of vertebral compression fractures
Towards a unified approach: Standardising radiological diagnosis and grading of vertebral compression fractures Open
Vertebral fragility fractures are a common cause of morbidity in osteoporotic patients. Despite their association with a high risk of future fractures, significant morbidity and increased mortality after fracture, they often do not receive…
View article: The distinct functional brain network and its association with psychotic symptom severity in men with methamphetamine-associated psychosis
The distinct functional brain network and its association with psychotic symptom severity in men with methamphetamine-associated psychosis Open
Background Individuals using methamphetamine (METH) may experience psychosis, which usually requires aggressive treatment. Studies of the neural correlates of METH-associated psychosis (MAP) have focused predominantly on the default mode n…
View article: Repeated CT scans on 12,984 Asians to diagnose lung cancer once it is suspected
Repeated CT scans on 12,984 Asians to diagnose lung cancer once it is suspected Open
In Taiwan, lung cancer remains the leading cause of cancer-related fatalities, resulting in substantial healthcare expenses. This research aims to evaluate both the frequency and the costs of low-dose computed tomography (LDCT) in individu…
View article: Breast cancer incidence in mobile screening vs. in-hospital screening programmes based on 6 313 607 mammograms in 2 387 756 women in Taiwan
Breast cancer incidence in mobile screening vs. in-hospital screening programmes based on 6 313 607 mammograms in 2 387 756 women in Taiwan Open
BACKGROUND: Since 2010, Taiwan has conducted a population-based breast cancer screening programme that includes mobile units to improve the screening rate. This study aimed to compare the results of mobile breast cancer screening units wit…
View article: Modelling future bone mineral density: Simplicity or complexity?
Modelling future bone mineral density: Simplicity or complexity? Open
Deep learning-based and statistical models have potential to forecast future BMD using longitudinal clinical data. These methods have the potential to augment clinical decisions regarding when to repeat BMD testing in the assessment of ost…
View article: Association between repeat imaging and readmission in patients with acute ischaemic stroke: a 16-year nationwide population-based study
Association between repeat imaging and readmission in patients with acute ischaemic stroke: a 16-year nationwide population-based study Open
Objectives This study aims to evaluate such usage patterns and identify factors that may contribute to the need for repeat imaging in acute ischaemic stroke patients and determine the association between repeat imaging and readmission in T…
View article: More evidence to support a lower quantitative computed tomography (QCT) lumbar spine bone mineral density (BMD) cutpoint value for classifying osteoporosis among older East Asian women than for Caucasians
More evidence to support a lower quantitative computed tomography (QCT) lumbar spine bone mineral density (BMD) cutpoint value for classifying osteoporosis among older East Asian women than for Caucasians Open
More evidence to support a lower quantitative computed tomography (QCT) lumbar spine bone mineral density (BMD) cutpoint value for classifying osteoporosis among older East Asian women than for Caucasians
View article: Androgenetic Alopecia: update on Etiology, Pathophysiology, Diagnosis and Treatment
Androgenetic Alopecia: update on Etiology, Pathophysiology, Diagnosis and Treatment Open
Alopecia means loss of hair. Androgenetic alopecia (AGA) now called as patterned hair loss (male pattern hair loss; MPHL, female pattern hair loss; FPHL) is caused by androgens in a predisposed individual. It is modulated by factors like a…
View article: Anti-osteoporosis drugs reduce mortality in cancer patients: A national cohort study of elderly with vertebral fractures
Anti-osteoporosis drugs reduce mortality in cancer patients: A national cohort study of elderly with vertebral fractures Open
Introduction: The most prevalent type of fragility fractures is osteoporotic vertebral fractures (OVFs). However, only a few studies have examined the relationship between anti-osteoporosis treatments and malignancy-related mortality follo…
View article: Machine learning models using multiparametric MRI for preoperative risk stratification in endometrial cancer
Machine learning models using multiparametric MRI for preoperative risk stratification in endometrial cancer Open
This study evaluated the efficacy of machine learning and radiomics of preoperative multiparameter MRIs in predicting low- vs high-risk histopathologic features and early vs advanced FIGO stage (IA vs IB or higher) in endometrial cancer. T…
View article: Automated osteoporosis classification and <i>T</i>-score prediction using hip radiographs <i>via</i> deep learning algorithm
Automated osteoporosis classification and <i>T</i>-score prediction using hip radiographs <i>via</i> deep learning algorithm Open
Background: Despite being the gold standard for diagnosing osteoporosis, dual-energy X-ray absorptiometry (DXA) is an underutilized screening tool for osteoporosis. Objectives: This study proposed and validated a controllable feature layer…
View article: Performance measures of 8,169,869 examinations in the National Breast Cancer Screening Program in Taiwan, 2004–2020
Performance measures of 8,169,869 examinations in the National Breast Cancer Screening Program in Taiwan, 2004–2020 Open
Background The benefits of mammographic screening have been shown to include a decrease in mortality due to breast cancer. Taiwan’s Breast Cancer Screening Program is a national screening program that has offered biennial mammographic brea…
View article: Prevalence of Low Bone Mass and Osteoporosis in Ireland: the Dual‐Energy X‐Ray Absorptiometry (DXA) Health Informatics Prediction (HIP) Project
Prevalence of Low Bone Mass and Osteoporosis in Ireland: the Dual‐Energy X‐Ray Absorptiometry (DXA) Health Informatics Prediction (HIP) Project Open
Osteoporosis is a common disease that has a significant impact on patients, healthcare systems, and society. World Health Organization (WHO) diagnostic criteria for postmenopausal women were established in 1994 to diagnose low bone mass (o…
View article: Current Progress of Platelet-Rich Derivatives in Cartilage and Joint Repairs
Current Progress of Platelet-Rich Derivatives in Cartilage and Joint Repairs Open
In recent years, several types of platelet concentrates have been investigated and applied in many fields, particularly in the musculoskeletal system. Platelet-rich fibrin (PRF) is an autologous biomaterial, a second-generation platelet co…
View article: Natural history and survival rate of familial amyloidosis with polyneuropathy: A nationwide databank
Natural history and survival rate of familial amyloidosis with polyneuropathy: A nationwide databank Open
Objective Hereditary amyloid transthyretin (ATTRv) amyloidosis with polyneuropathy, a rare autosomal‐dominant disease, has gained attention in recent years owing to treatment improvements. However, epidemiological real‐world mega database …
View article: Effectiveness of Repetitive Transcranial Magnetic Stimulation Combined with Transspinal Electrical Stimulation on Corticospinal Excitability for Individuals with Incomplete Spinal Cord Injury: A Pilot Study
Effectiveness of Repetitive Transcranial Magnetic Stimulation Combined with Transspinal Electrical Stimulation on Corticospinal Excitability for Individuals with Incomplete Spinal Cord Injury: A Pilot Study Open
Repetitive Transcranial Magnetic Stimulation (rTMS) and transspinal electrical stimulation (tsES) have been proposed as a novel neurostimulation modality for individuals with incomplete spinal cord injury (iSCI). In this study, we integrat…
View article: Automatic Calcification Morphology and Distribution Classification for Breast Mammograms With Multi-Task Graph Convolutional Neural Network
Automatic Calcification Morphology and Distribution Classification for Breast Mammograms With Multi-Task Graph Convolutional Neural Network Open
The morphology and distribution of microcalcifications are the most important descriptors for radiologists to diagnose breast cancer based on mammograms. However, it is very challenging and time-consuming for radiologists to characterize t…
View article: Utilization of CT and MRI scanning in Taiwan, 2000–2017
Utilization of CT and MRI scanning in Taiwan, 2000–2017 Open
Objectives This population-based study aimed to collect, analyze, and summarize the long-term trends in medical imaging use in Taiwan. Methods A retrospective cohort population-based study of medical imaging usage for the individuals who r…
View article: <i>T</i>-score discordance between hip and lumbar spine: risk factors and clinical implications
<i>T</i>-score discordance between hip and lumbar spine: risk factors and clinical implications Open
Background: T-score discordance is common in osteoporosis diagnosis and leads to problems for clinicians formulating treatment plans. Objectives: This study investigated the potential predictors of T-score discordance and compared fracture…
View article: Lymphoma Spectrum of Image Findings in One Patient
Lymphoma Spectrum of Image Findings in One Patient Open
Lymphoma is a malignancy arising from lymphocytes or lymphoblasts. It affects the lymphoid system and may be expressed in a variety of ways and behave in different fashions. Depending on the organ involved, aggressiveness, and primary or s…
View article: Asia–pacific consensus on osteoporotic fracture prevention in postmenopausal women with low bone mass or osteoporosis but no fragility fractures
Asia–pacific consensus on osteoporotic fracture prevention in postmenopausal women with low bone mass or osteoporosis but no fragility fractures Open
Postmenopausal women are at significant risk for osteoporotic fractures due to their rapid bone loss. Half of all postmenopausal women will get an osteoporosis-related fracture over their lifetime, with 25% developing a spine deformity and…
View article: Clinical practice guidelines for the prevention and treatment of osteoporosis in Taiwan: 2022 update
Clinical practice guidelines for the prevention and treatment of osteoporosis in Taiwan: 2022 update Open
Osteoporosis greatly increases the risk of fractures. Osteoporotic fractures negatively impact quality of life, increase the burden of care, and increase mortality. Taiwan is an area with a high prevalence of osteoporosis. This updated sum…
View article: Effectiveness of Repetitive Transcranial Magnetic Stimulation Combined With Transspinal Electrical Stimulation on Corticospinal Excitability for Individuals With Incomplete Spinal Cord Injury: A Pilot Study
Effectiveness of Repetitive Transcranial Magnetic Stimulation Combined With Transspinal Electrical Stimulation on Corticospinal Excitability for Individuals With Incomplete Spinal Cord Injury: A Pilot Study Open
Repetitive Transcranial Magnetic Stimulation (rTMS) and transspinal electrical stimulation (tsES) have been proposed as a novel neurostimulation modality for individuals with incomplete spinal cord injury (iSCI). In this study, we integrat…
View article: Radiologist burnout: Trends in medical imaging utilization under the national health insurance system with the universal code bundling strategy in an academic tertiary medical centre
Radiologist burnout: Trends in medical imaging utilization under the national health insurance system with the universal code bundling strategy in an academic tertiary medical centre Open
Imaging utilization increased significantly under the NHI system at a medical centre. The corresponding demand for image interpretation also placed a significant workload on radiologists, potentially contributing to radiologist burnout.