Pooja Jaiswal
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View article: Correlation of optic nerve sheath diameter (ONSD) assessed by computed tomography (CT) with Glasgow coma scale (GCS) in patients with traumatic brain injury in tertiary care hospital of Nepal
Correlation of optic nerve sheath diameter (ONSD) assessed by computed tomography (CT) with Glasgow coma scale (GCS) in patients with traumatic brain injury in tertiary care hospital of Nepal Open
Introduction: The optic nerve sheath, an extension of the dura mater and subarachnoid space filled with cerebrospinal fluid (CSF), connects to the CSF area around the optic nerve. Increased CSF pressure from brain edema can enlarge the she…
View article: Diagnostic Accuracy of High Resolution Computed Tomography Chest in Active Pulmonary Tuberculosis
Diagnostic Accuracy of High Resolution Computed Tomography Chest in Active Pulmonary Tuberculosis Open
Introduction: Pulmonary Tuberculosis is a common health problem in our country. It is one of the top 10 causes of death in Nepal. The diagnostic guidelines are primarily based on Acid Fast Baccili (AFB) smear on sputum and Gene Xpert test.…
View article: Accuracy of Computed Tomography Attenuation Values in Differentiating Transudative from Exudative Pleural Effusion
Accuracy of Computed Tomography Attenuation Values in Differentiating Transudative from Exudative Pleural Effusion Open
Introduction: Pleural effusion, the accumulation of fluid between the lungs and chest wall, arises from various diseases. Differentiating transudative from exudative effusions is essential for diagnosis and management. While thoracentesis …
View article: Serum Lipid Abnormalities in Pre-malignant and Malignant Lesions of the Gall Bladder
Serum Lipid Abnormalities in Pre-malignant and Malignant Lesions of the Gall Bladder Open
Progressive lipid derangements - particularly hypertriglyceridemia, elevated VLDL, and reduced HDL - are associated with malignant transformation in gallbladder lesions. Serum lipid profiling may serve as a non-invasive tool for risk strat…
View article: Assessment of Stromal Calretinin Expression in Normal and Pathological Endometrium of Patients With Abnormal Uterine Bleeding
Assessment of Stromal Calretinin Expression in Normal and Pathological Endometrium of Patients With Abnormal Uterine Bleeding Open
Stromal calretinin expression was substantially reduced in AUB-related endometrial lesions compared to normal endometrium. These findings suggest its potential utility as a supplementary biomarker for distinguishing between physiological a…
View article: The Yellow Fever Vaccine Journey: Milestones and Future Directions
The Yellow Fever Vaccine Journey: Milestones and Future Directions Open
Yellow fever, a viral hemorrhagic disease transmitted by mosquitoes, poses a significant public health issue in regions of Africa and South America where it is prevalent. Researchers believe that the development of the yellow fever vaccine…
View article: Biomass Briquette from Agriculture Waste
Biomass Briquette from Agriculture Waste Open
View article: Analysis of metagenomic data
Analysis of metagenomic data Open
View article: Management of intracranial meningioma: Outcome analysis and clinico radiological profile of 172 patients
Management of intracranial meningioma: Outcome analysis and clinico radiological profile of 172 patients Open
Background: Meningioma is the most common primary intracranial tumor. This single-center study aimed to analyze the clinicopathological, radiological profile, and outcomes of patients with intracranial meningiomas in terms of functional st…
View article: Diagnostic accuracy of ultrasonography and mammography of breast lesions
Diagnostic accuracy of ultrasonography and mammography of breast lesions Open
Introduction: Breast cancer is the most common malignant tumors in women, with over one million cases diagnosed globally each year, resulting in approximately 410,000 deaths. Early detection and treatment significantly reduce the risk of m…
View article: Pharmacological Evaluation of Anti-Inflammatory and Antioxidant Potential of Cuscuta Reflexa Methanol Extract: Role in Inhibition of Cyclooxygenase and Lipooxygenase
Pharmacological Evaluation of Anti-Inflammatory and Antioxidant Potential of Cuscuta Reflexa Methanol Extract: Role in Inhibition of Cyclooxygenase and Lipooxygenase Open
In this study, the antioxidant and anti-inflammatory properties of the methanol extract of Cuscuta reflexa (CRWP-M) were evaluated. The plant material was collected from Dehradun and processed to obtain the extract, which was tested for it…
View article: Efficacy of Dexamethasone in Reducing Postoperative Symptoms of the Surgical Extraction of Impacted Third Molars
Efficacy of Dexamethasone in Reducing Postoperative Symptoms of the Surgical Extraction of Impacted Third Molars Open
View article: Therapeutic influence of simvastatin on MCF-7 and MDA-MB-231 breast cancer cells via mitochondrial depletion and improvement in chemosensitivity of cytotoxic drugs
Therapeutic influence of simvastatin on MCF-7 and MDA-MB-231 breast cancer cells via mitochondrial depletion and improvement in chemosensitivity of cytotoxic drugs Open
Background: Breast cancer is the most commonly diagnosed cancer worldwide with 2.26 million cases in 2020. Cancer heterogeneity is the major challenge before existing therapeutic modalities due to metabolic variability of the cells as Warb…
View article: A rigorous benchmarking of methods for SARS-CoV-2 lineage abundance estimation in wastewater
A rigorous benchmarking of methods for SARS-CoV-2 lineage abundance estimation in wastewater Open
In light of the continuous transmission and evolution of SARS-CoV-2 coupled with a significant decline in clinical testing, there is a pressing need for scalable, cost-effective, long-term, passive surveillance tools to effectively monitor…
View article: Cover Feature: Catalytic Deactivation and Regeneration of Nickel Microparticles in a Home‐Built Microchannel‐Coupled Millireactor: Substrate Specificity and Multiphase Flow Dependency (ChemPhysChem 14/2023)
Cover Feature: Catalytic Deactivation and Regeneration of Nickel Microparticles in a Home‐Built Microchannel‐Coupled Millireactor: Substrate Specificity and Multiphase Flow Dependency (ChemPhysChem 14/2023) Open
Graphical Abstract The Cover Feature illustrates deactivation and regeneration of nickel catalyst in a microchannel-coupled-millireactor. During continuous operation, millireactors show strong catalytic activity for reduction of resazurin …
View article: A Comparison Between the Effectiveness of Isoamyl 2-Cyanoacrylate Tissue Adhesive and Silk Sutures in Wound Closure Following Minor Oral Surgical Procedures: A Prospective Clinical Study
A Comparison Between the Effectiveness of Isoamyl 2-Cyanoacrylate Tissue Adhesive and Silk Sutures in Wound Closure Following Minor Oral Surgical Procedures: A Prospective Clinical Study Open
View article: Novel HPTLC Method for Estimation of Fluocinonide
Novel HPTLC Method for Estimation of Fluocinonide Open
View article: Role of S-100 stain for demonstration of different patterns of nerve changes in spectrum of leprosy – A prospective study
Role of S-100 stain for demonstration of different patterns of nerve changes in spectrum of leprosy – A prospective study Open
Background: A confirmatory diagnosis of tuberculoid (TL) and borderline TL (BTL) leprosy is dependent on the demonstration of nerve involvement within granuloma or acid-fast bacilli. It is very difficult to identify nerve elements in hemat…
View article: LBSUN208 Patient Education And Addressal Of Social Determinants Of Health: Key To Improvement In Diabetes Care
LBSUN208 Patient Education And Addressal Of Social Determinants Of Health: Key To Improvement In Diabetes Care Open
As per American Diabetes Association, diabetes is a 'complex chronic illness requiring continuous medical care with multifactorial risk reduction strategies beyond glycemic control'. In 2018, the prevalence of diabetes mellitus in the US p…
View article: Repurposing of metabolic drugs and mitochondrial modulators as an emerging class of cancer therapeutics with a special focus on breast cancer
Repurposing of metabolic drugs and mitochondrial modulators as an emerging class of cancer therapeutics with a special focus on breast cancer Open
View article: Incidence of Ectopic Pregnancy and its Diagnostic Accuracy by Clinical, Ultrasound and Intraoperative Findings
Incidence of Ectopic Pregnancy and its Diagnostic Accuracy by Clinical, Ultrasound and Intraoperative Findings Open
Introduction: In an ectopic pregnancy, most patients present with 5 to 9 weeks of amenorrhea, mild pelvic pain and vaginal spotting which triggers the evaluation of ectopic pregnancy. The presence of an extrauterine gestational sac contain…
View article: CT KUB evaluation of suspected urolithiasis
CT KUB evaluation of suspected urolithiasis Open
Introduction: Non-contrasted computed tomography scan for kidney, ureter, and bladder (CT KUB) for diagnosis of urolithiasis is important for accurate diagnosis, followup, and management. Unlike USG, CT KUB has more diagnostic yield in uro…
View article: Parasitic infections encountered by a cytopathologist: An institutional experience
Parasitic infections encountered by a cytopathologist: An institutional experience Open
Background: Parasitic infections are one of the leading causes of morbidity and mortality worldwide. Cytological examination can be of great help in providing economical, accurate, and fast diagnosis. Aims and Objectives: The aim of the st…
View article: Spectrum of Orbito-ocular Tumour in India: Histopathological and Immunohistochemical Study
Spectrum of Orbito-ocular Tumour in India: Histopathological and Immunohistochemical Study Open
Introduction: Orbito-ocular tumours are an important cause of morbidity and mortality. Their incidence is low but requires immediate diagnosis and treatment. There are limited research studies on histopathological and immunohistochemical s…
View article: Anti-cancer effects of sitagliptin, vildagliptin, and exendin-4 on triple-negative breast cancer cells via mitochondrial modulation
Anti-cancer effects of sitagliptin, vildagliptin, and exendin-4 on triple-negative breast cancer cells via mitochondrial modulation Open
Triple-negative breast cancer (TNBC) cell line MDA-MB-231 is known for Warburg metabolism and defects in mitochondria. On the other hand, dipeptidyl peptidase-IV (DPP-IV) inhibitors such as sitagliptin and vildagliptin and GLP-1 agonist ex…
View article: Repurposing of Metabolic Drugs and Mitochondrial Modulators as an Emerging Class of Cancer Therapeutics with a Special Focus on Breast Cancer
Repurposing of Metabolic Drugs and Mitochondrial Modulators as an Emerging Class of Cancer Therapeutics with a Special Focus on Breast Cancer Open
View article: Comparison of ultrasound and Contrast- enhanced computed tomography in clinically diagnosed cases of acute pancreatitis
Comparison of ultrasound and Contrast- enhanced computed tomography in clinically diagnosed cases of acute pancreatitis Open
Introduction: Acute pancreatitis (AP) is an acute, mainly diffuse, inflammatory process of the pancreas with dynamic imaging characteristics and a multitude of possible complications. Imaging plays an important role in the diagnosis of AP.…
View article: Nanomaterials: stimulants for biofuels and renewables, yield and energy optimization
Nanomaterials: stimulants for biofuels and renewables, yield and energy optimization Open
Nanoparticles play a vital role in energy and yield optimization of biofuels for competitive cost and commerical production. The role of nanomaterials, functions, various characterization techniques, nucleation and growth kinetics have bee…
View article: Correlation of ultrasound imaging with histopathological findings in gestational trophoblastic disease
Correlation of ultrasound imaging with histopathological findings in gestational trophoblastic disease Open
Introduction: Gestational trophoblastic diseases include a spectrum of pregnancy-related diseases caused by abnormal proliferation of the placenta. The main aim of this study was to correlate ultrasound imaging with histopathological findi…
View article: Endoscopic transcortical transventricular management of cystic craniopharyngioma: Outcome analysis of 32 cases at a tertiary care center
Endoscopic transcortical transventricular management of cystic craniopharyngioma: Outcome analysis of 32 cases at a tertiary care center Open
Background: Microsurgical resection has been considered the gold standard treatment of craniopharyngioma, but lately, it has found less favor due to its morbidity and is being replaced by minimally invasive cyst drainage procedures. We pre…