Poonam Suryawanshi
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View article: Daily intranasal sesame oil instillation to improve nasal barrier function and mucosal immunity for respiratory health: A pilot randomized trial in healthy adults
Daily intranasal sesame oil instillation to improve nasal barrier function and mucosal immunity for respiratory health: A pilot randomized trial in healthy adults Open
Feasibility and preliminary efficacy of self-administered intranasal sesame oil instillation is demonstrated. A definitive RCT to evaluate it as a prophylaxis for respiratory health is needed.
View article: Scrub Typhus taking Center Stage again!
Scrub Typhus taking Center Stage again! Open
There is alarming increase in scrub typhus cases in Hyderabad, the city is grappling not only with dengue and flu but also with this emerging health issue. The disease is typically associated with rural areas, now f inding its way into urb…
View article: Undiagnosed Sleep Apnea: Exacerbating the Postcoronavirus Disease Symptoms?
Undiagnosed Sleep Apnea: Exacerbating the Postcoronavirus Disease Symptoms? Open
View article: Galangin promotes apoptosis by upregulating the pro-apoptotic gene BAX in triple-negative breast cancer
Galangin promotes apoptosis by upregulating the pro-apoptotic gene BAX in triple-negative breast cancer Open
Background Triple-negative breast cancer (TNBC) is one of the most aggressive and formidable subtypes of breast cancer, devoid of targeted therapy and frequently leading to unfavorable prognoses and significant side effects. The demand for…
View article: Assessment of Anti-spike and Neutralizing Antibody Response Against SARS-CoV-2 after Covishield and CovaxinTM Vaccination
Assessment of Anti-spike and Neutralizing Antibody Response Against SARS-CoV-2 after Covishield and CovaxinTM Vaccination Open
A BSTRACT Introduction: This study was conducted to determine total and neutralizing antibody (nAb) titer in individuals at an interval of 2 and 6 months after primary vaccination and after 1 month after administration of booster dose. Mat…
View article: Unveiling the Quest: Crafting an Enzyme-Linked Immunosorbent Assay (ELISA) Technique to Uncover COVID-19 Antibodies
Unveiling the Quest: Crafting an Enzyme-Linked Immunosorbent Assay (ELISA) Technique to Uncover COVID-19 Antibodies Open
The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has had a profound impact on global health. Rapid and accurate diagnostic tools are crucial for effective disease control and management. The enzyme-linked immunosorbent as…
View article: T‐cell responses in COVID‐19 survivors 6−8 months after infection: A longitudinal cohort study in Pune
T‐cell responses in COVID‐19 survivors 6−8 months after infection: A longitudinal cohort study in Pune Open
Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) immune response is crucial for disease management, although diminishing immunity raises the possibility of reinfection. Methods We examined the immunological respo…
View article: T-cell responses in COVID-19 survivors six to eight months after infection: a longitudinal cohort study in Pune
T-cell responses in COVID-19 survivors six to eight months after infection: a longitudinal cohort study in Pune Open
The SARS-CoV-2 immune response is crucial for disease management, although diminishing immunity raises the possibility of reinfection. In matched samples collected at one month and six to eight months after infection, we examined the immun…
View article: Liquid Biopsy: A New Torchbearer in the Ever-Evolving Landscape of Breast Cancer Diagnosis
Liquid Biopsy: A New Torchbearer in the Ever-Evolving Landscape of Breast Cancer Diagnosis Open
View article: Management of Nipah outbreak in India: A plea for immediate action
Management of Nipah outbreak in India: A plea for immediate action Open
View article: Neutralizing Antibodies against SARS-CoV2
Neutralizing Antibodies against SARS-CoV2 Open
A BSTRACT Coronavirus disease 2019 (COVID-19) is an illness due to a novel coronavirus which is Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Though this virus is recently identified in 2019, it is closely related to other …
View article: Clinical, immunological and genomic analysis of the post vaccinated SARS-CoV-2 infected cases with Delta derivatives from Maharashtra, India, 2021
Clinical, immunological and genomic analysis of the post vaccinated SARS-CoV-2 infected cases with Delta derivatives from Maharashtra, India, 2021 Open
View article: Peripheral lymphocyte subset alteration in patients with COVID-19 having differential clinical manifestations
Peripheral lymphocyte subset alteration in patients with COVID-19 having differential clinical manifestations Open
Background & objectives The COVID-19 disease profile in Indian patients has been found to be different from the Western world. Changes in lymphocyte compartment have been correlated with disease course, illness severity and clinical outcom…
View article: Anti-HIV-1 ADCC and HIV-1 Env Can Be Partners in Reducing Latent HIV Reservoir
Anti-HIV-1 ADCC and HIV-1 Env Can Be Partners in Reducing Latent HIV Reservoir Open
Background Persistence of HIV reservoir even in suppressive ART is the key obstacle in HIV-1 cure. We evaluated the ability of HIV-1 C Env to reactivate the latently infected resting memory CD4 cells and the ability of polyclonal HIV antib…
View article: Higher expression of human telomerase reverse transcriptase in productively‐infected CD4 cells possibly indicates a mechanism for persistence of the virus in HIV infection
Higher expression of human telomerase reverse transcriptase in productively‐infected CD4 cells possibly indicates a mechanism for persistence of the virus in HIV infection Open
Mechanisms involved in survival of productively‐infected memory CD4+cells after initial antigenic stimulation and their subsequent reversion to the resting state are critical for the development of a predominant replication‐competent HIV r…
View article: <scp>HIV</scp>‐infected <scp>CD</scp>4+ T Cells Use T‐bet‐dependent Pathway for Production of <scp>IL</scp>‐10 Upon Antigen Recognition
<span>HIV</span>‐infected <span>CD</span>4+ T Cells Use T‐bet‐dependent Pathway for Production of <span>IL</span>‐10 Upon Antigen Recognition Open
Interleukin ( IL )‐10 has been implicated in persistence of pathogens in a number of chronic infections. Infected CD 4+ cells upon reactivation with HIV antigens were also shown to produce IL ‐10, which might contribute to their persistenc…