Poorani Sekar
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View article: A comparison of the clinical characteristics and outcomes of aerobic and anaerobic prosthetic joint infections (PJIs): a single-center retrospective review
A comparison of the clinical characteristics and outcomes of aerobic and anaerobic prosthetic joint infections (PJIs): a single-center retrospective review Open
Background: Prosthetic joint infection (PJI) is an uncommon but serious complication of joint arthroplasty, associated with significant morbidity and healthcare costs. Anaerobic organisms are an under-recognized cause of PJI, either as sol…
View article: Decisions About Suppressive Antibiotics Among Clinicians at Veterans Affairs Hospitals After Prosthetic Joint Infection
Decisions About Suppressive Antibiotics Among Clinicians at Veterans Affairs Hospitals After Prosthetic Joint Infection Open
Importance Indefinite suppressive antibiotic therapy (SAT) is sometimes prescribed after initial antibiotic treatment for prosthetic joint infection (PJI). Limited evidence on outcomes after SAT exists, and using SAT for patients at low ri…
View article: Pro-inflammatory secreted virulence factors of <i>Staphylococcus capitis</i> causing a rare occurrence of severe native hip joint infection
Pro-inflammatory secreted virulence factors of <i>Staphylococcus capitis</i> causing a rare occurrence of severe native hip joint infection Open
Background Staphylococcus capitis occasionally causes human infections. We report a case of S. capitis infection associated with inflammatory destructive hip abscess/osteomyelitis. Case Summary A 63-year-old man with severe hip osteoarthri…
View article: Extensor tenosynovitis and subcutaneous abscess caused by hypervirulent Klebsiella pneumoniae
Extensor tenosynovitis and subcutaneous abscess caused by hypervirulent Klebsiella pneumoniae Open
We report a rare case of invasive Klebsiella pneumoniae infection in a previously healthy 52-year-old Japanese man who presented with extensor tenosynovitis associated with subcutaneous abscess of the right hand, in the setting of concomit…
View article: Variation in North American Infectious Disease Specialists' Practice Regarding Oral and Suppressive Antibiotics for Adult Osteoarticular Infections: Results of an Emerging Infections Network (EIN) Survey
Variation in North American Infectious Disease Specialists' Practice Regarding Oral and Suppressive Antibiotics for Adult Osteoarticular Infections: Results of an Emerging Infections Network (EIN) Survey Open
Background Osteoarticular infections (OAIs) are commonly treated with prolonged intravenous (IV) antimicrobials. The Oral versus Intravenous Antibiotics for Bone and Joint Infection (OVIVA) trial demonstrated that oral (PO) antibiotics are…
View article: Disseminated Mycobacterium chimaera infection successfully treated with a clofazimine-containing regimen and long-term follow-up after discontinuing treatment
Disseminated Mycobacterium chimaera infection successfully treated with a clofazimine-containing regimen and long-term follow-up after discontinuing treatment Open
View article: 1305. Current Management of Osteoarticular Infections by Infectious Diseases Physicians: Results of an Emerging Infections Network (EIN) Survey
1305. Current Management of Osteoarticular Infections by Infectious Diseases Physicians: Results of an Emerging Infections Network (EIN) Survey Open
Background Osteoarticular infections (OAI) have been commonly treated with prolonged intravenous (IV) antimicrobials. The Oral versus Intravenous Antibiotics for Bone and Joint Infection (OVIVA) trial demonstrated that oral (PO) antibiotic…
View article: 1306. Lower Treatment Failure Rates in Patients with Non-Staphylococcal Prosthetic Joint Infections (PJI) Treated with Debridement and Implant Retention (DAIR) Receiving Chronic Antibiotic Suppression (CAS)
1306. Lower Treatment Failure Rates in Patients with Non-Staphylococcal Prosthetic Joint Infections (PJI) Treated with Debridement and Implant Retention (DAIR) Receiving Chronic Antibiotic Suppression (CAS) Open
Background PJI occurs in 0.5-2% of Joint Arthroplasty. Patients with acute non-Staphylococcal PJI who undergo DAIR are treated with 6 weeks of antimicrobials after which CAS may be considered. We aimed to compare the incidence of treatment…
View article: 1300. Comparison of the Clinical Characteristics and Outcomes of Anaerobic Prosthetic Joint Infections (PJI) and Aerobic PJIs : A Retrospective Review
1300. Comparison of the Clinical Characteristics and Outcomes of Anaerobic Prosthetic Joint Infections (PJI) and Aerobic PJIs : A Retrospective Review Open
Background PJI is an uncommon but serious complication of joint arthroplasties that can result in significant morbidity and cost. There is a paucity of studies in the literature on PJIs caused by anaerobic organisms either as the sole path…
View article: CNS toxoplasmosis, a rare presentation in a patient with Myasthenia Gravis
CNS toxoplasmosis, a rare presentation in a patient with Myasthenia Gravis Open
We report the case of a 78-year-old man with a past medical history of non-Hodgkin's lymphoma s/p chemotherapy and Myasthenia Gravis on chronic mycophenolate mofetil (MMF), who presented with altered mental status and was found to have rin…
View article: Hip periprosthetic joint infection due to Coxiella burnetii in an adult male
Hip periprosthetic joint infection due to Coxiella burnetii in an adult male Open
View article: Rates of Antimicrobial Resistance With Extended Oral Antibiotic Prophylaxis After Total Joint Arthroplasty
Rates of Antimicrobial Resistance With Extended Oral Antibiotic Prophylaxis After Total Joint Arthroplasty Open
Level III; retrospective cohort study.
View article: Effectiveness and Optimal Duration of Adjunctive Rifampin Treatment in the Management of <i>Staphylococcus aureus</i> Prosthetic Joint Infections After Debridement, Antibiotics, and Implant Retention
Effectiveness and Optimal Duration of Adjunctive Rifampin Treatment in the Management of <i>Staphylococcus aureus</i> Prosthetic Joint Infections After Debridement, Antibiotics, and Implant Retention Open
Background Rifampin is recommended as adjunctive therapy for patients with a Staphylococcus aureus prosthetic joint infection (PJI) managed with debridement, antibiotics, and implant retention (DAIR), with no solid consensus on the optimal…
View article: Feasibility and acceptability of intranasal povidone iodine decolonization among orthopedic trauma surgery patients
Feasibility and acceptability of intranasal povidone iodine decolonization among orthopedic trauma surgery patients Open
Background: Nasal decolonization significantly decreases the incidence of Staphylococcus aureus surgical-site infections (SSIs). Patient adherence with self-administration of a decolonization ointment (ie, mupirocin) is low, especially amo…
View article: Extra-articular tophaceous gout of the Achilles tendon mimicking infection
Extra-articular tophaceous gout of the Achilles tendon mimicking infection Open
A 49-year-old man with remote history of traumatic right Achilles tendon rupture from a sports injury treated with primary repair using non-absorbable suture material and flexor hallucis longus tendon transfer presented with several weeks …
View article: Prosthetic hip infection due to <i>Campylobacter jejuni</i>
Prosthetic hip infection due to <i>Campylobacter jejuni</i> Open
A woman in her 60s with a left hip prosthesis was presented with left hip pain and fever. She had an elevated white blood cell count and inflammatory markers. Synovial fluid Gram stain demonstrated curved Gram-negative rods identified as C…
View article: 235. Outcomes Associated with Extended Oral Antibiotic Prophylaxis After 2-Stage Exchange Surgery to Prevent Recurrent Prosthetic Joint Infection
235. Outcomes Associated with Extended Oral Antibiotic Prophylaxis After 2-Stage Exchange Surgery to Prevent Recurrent Prosthetic Joint Infection Open
Background 2-stage exchange (2SE) surgery is often used to treat chronic prosthetic joint infections (PJI). IDSA guidelines do not recommend oral antibiotic suppression after 2SE. However, a recent randomized trial suggested that oral anti…
View article: 92. Clinical Decision-Making about Chronic Antibiotic Suppression after Prosthetic Joint Infection Treatment: Qualitative Insights for Antibiotic Stewardship
92. Clinical Decision-Making about Chronic Antibiotic Suppression after Prosthetic Joint Infection Treatment: Qualitative Insights for Antibiotic Stewardship Open
Background Patients who develop prosthetic joint infections (PJI) may be prescribed chronic antibiotic suppression (CAS) ( > 6 months of antibiotics) after initial antibiotic treatment for the PJI. Patients at low risk of recurrent infe…
View article: Chronic Antibiotic Suppression for Nonstaphylococcal Prosthetic Joint Infections Treated with Debridement or Implant Retention
Chronic Antibiotic Suppression for Nonstaphylococcal Prosthetic Joint Infections Treated with Debridement or Implant Retention Open
Background: Early postoperative and acute prosthetic joint infection (PJI) may be managed with debridement, antibiotics, and implant retention (DAIR). Among patients with nonstaphylococcal PJI, an initial 4–6-week course of intravenous or …
View article: Recurrent <i>Cutibacterium acnes</i> prosthetic valve endocarditis
Recurrent <i>Cutibacterium acnes</i> prosthetic valve endocarditis Open
A 29-year-old man with a history of congenital aortic stenosis and mechanical aortic valve replacement with previous Cutibacterium acnes prosthetic valve endocarditis (PVE) presented with a 2-week history of fevers and night sweats. Transo…
View article: Antibody testing to distinguish between histoplasmosis and blastomycosis
Antibody testing to distinguish between histoplasmosis and blastomycosis Open
A 35-year-old man presented to the emergency department with headaches, productive cough and fevers to 39°C. Medical history was significant for chronic back pain. He lived in the Midwest USA, smoked 20 cigarettes a day, drank alcohol soci…
View article: Native joint septic arthritis due to Kingella kingae in an adult
Native joint septic arthritis due to Kingella kingae in an adult Open
View article: Prosthetic hip infection due to Salmonella enterica serovar Enteritidis
Prosthetic hip infection due to Salmonella enterica serovar Enteritidis Open
View article: <i>Staphylococcus aureus</i> osteomyelitis causing Brodie’s abscess of the tibia in an adult man
<i>Staphylococcus aureus</i> osteomyelitis causing Brodie’s abscess of the tibia in an adult man Open
A 50-year-old man with a childhood history of right tibial fracture managed non-operatively with traction pin placement was referred to the orthopaedics clinic. He had several months of worsening right lower leg pain, warmth and swelling i…
View article: Prosthetic Finger Joint Infection Due to <i>Aspergillus terreus</i>
Prosthetic Finger Joint Infection Due to <i>Aspergillus terreus</i> Open
Fungal periprosthetic joint infections (PJIs) are rare but associated with significant mortality. We report a case of a finger PJI secondary to Aspergillus terreus in an immunocompetent patient with soil exposure, successfully treated with…
View article: Late prosthetic shoulder joint infection due to <i>Actinomyces neuii</i> in an adult man
Late prosthetic shoulder joint infection due to <i>Actinomyces neuii</i> in an adult man Open
A 72-year-old man with a history of right reverse shoulder arthroplasty presented with a 1-month history of erythema, pain and drainage from the right shoulder. Arthrocentesis was performed and synovial fluid gram stain revealed gram-posit…
View article: Osseous blastomycosis mimicking malignancy
Osseous blastomycosis mimicking malignancy Open
A 33-year-old man presented with a 10-month history of left back and flank pain with radiation to his lower extremity. The symptoms started gradually without preceding trauma or activity. He is a school teacher, living in the Midwestern Un…
View article: Disseminated histoplasmosis presenting as bilateral lower extremity paresis
Disseminated histoplasmosis presenting as bilateral lower extremity paresis Open
View article: <i>Escherichia hermannii</i> as the sole cause of osteomyelitis in a patient with an open tibial shaft fracture
<i>Escherichia hermannii</i> as the sole cause of osteomyelitis in a patient with an open tibial shaft fracture Open
Escherichia hermannii is a rare monomicrobial cause of infection in humans. E. hermannii has never before been reported as the sole isolate from an infected open tibia fracture. We present a case of E. hermannii infection after a type III …
View article: Current Evidence on Oral Antibiotics for Infective Endocarditis: A Narrative Review
Current Evidence on Oral Antibiotics for Infective Endocarditis: A Narrative Review Open