Explanipedia

Impact of Bacillus subtilis and Bacillus clausii Probiotic Supplementation on Broiler Performance Open

Pradip Barde, Ankur Khare, Sunil Nayak, Rahul Sharma, Nirmala Muwel , et al. · 2025

Background: Probiotics, defined as live microorganisms offering physiological benefits to their host. Among the Probiotics, Bacillus subtilis and Bacillus clausiihave been recognized as safe and effective. Study evaluated the effects of Ba…

Preliminary evaluation of inactivated antigens as diagnostic controls in molecular detection of vector-borne diseases in low-resource settings Open

M Harshavarthini, Subbiah Kombiah, Satyendra Pandey, Vagisha Rawal, Kumaramangalath Anjal , et al. · 2025

Background & objectives: Molecular tests play crucial role in diagnosis, however, acquiring appropriate controls is challenging owing to strict biosafety and biosecurity regulations. Herein, we suggest an alternative to live virus for incl…

Author Correction: A comprehensive overview of the burden, prevention, and therapeutic aspects of arboviral diseases in India Open

Himanshu Gupta, Pradip Barde, Mrigendra P. Singh, Praveen K. Bharti, Nitika Nitika · 2025

A comprehensive overview of the burden, prevention, and therapeutic aspects of arboviral diseases in India Open

Himanshu Gupta, Pradip Barde, Mrigendra P. Singh, Praveen K. Bharti, Nitika Nitika · 2025

Molecular detection and characterization of Hepatitis C virus in Central India Open

Subbiah Kombiah, R. P. Jishna, Afzal Ansari, Pradip Barde, Pushpendra Singh · 2025

Prospective Observational Study on Prevalence and Outcome of Congenital Abnormalities in Fetus in Tertiary Health Care Open

Ashwini Naik, Bushra Ansari, Amarjeet Bava, Pradip Barde, Ajay Naik · 2025

Emergence of scrub typhus-associated neurological signs in central India: An unusual manifestation in febrile illness cases in Madhya Pradesh, India Open

Gayatri Sondhiya, Prakash Tiwari, H. V. Manjunathachar, Vivek Chouksey, Pradeep Tiwari , et al. · 2025

Problem considered: Scrub typhus, a re-emerging zoonotic infection, often manifests as acute undifferentiated febrile illness (AUF), posing a significant epidemiological threat in tropical and subtropical regions. Its nonspecific clinical …

Molecular Characterization and Genomic Surveillance of SARS-CoV-2 Lineages in Central India Open

Purna Dwivedi, Mukul Sharma, Afzal Ansari, Arup Ghosh, Subasa C. Bishwal , et al. · 2024

Since the first reported case of COVID-19 in December 2019, several SARS-CoV-2 variants have evolved, and some of them have shown higher transmissibility, becoming the prevalent strains. Genomic epidemiological investigations into strains …

Leptospirosis in central India: A retrospective study to explore burden of tropical illness Open

H. V. Manjunathachar, Pradip Barde, Vivek Chouksey, Prakash Tiwari, Basavaraj Mathapati , et al. · 2024

Leptospirosis, an underdiagnosed zoonotic disease in India, was studied retrospectively in Madhya Pradesh, Central India. Between 2018 and 2019, 2617 samples from patients with hepatitis-related symptoms were collected. Of these, 518 teste…

Molecular Characterization and Genomic Surveillance of SARS-CoV-2 Lineages in Central India Open

Purna Dwivedi, Mukul Sharma, Afzal Ansari, Arup Ghosh, Subasa Chandra Bishwal , et al. · 2024

Since the first reported case of COVID-19 in December 2019, several SARS-CoV-2 variants has evolved and some of them have shown higher transmissibility becoming the prevalent strains. Genomic epidemiological investigations into strains fro…

Enhancing medical education: Evaluating the immediate and sustained impact of a basic course workshop in medical education technologies on faculty knowledge and teaching skills Open

Sanjay Gupta, Pradip Barde, Utsav Parekh · 2023

Emergence of Japanese encephalitis in eastern parts of Madhya Pradesh, India Open

Ashok Kumar, Shiv Singh Manjhi, Jeetendra Kumar Singh, Meena Patel, Deepak Dwivedi , et al. · 2022

Our results show that JEV is an emerging threat in eastern central India and health authorities need to be vigilant. A systematic molecular and serological survey among humans and animals along with xenomonitoring will help in understandin…

Use of dry blots for serotyping and genotyping of dengue viruses: A pilot study Open

Subasa Chandra Bishwal, Rakesh Kumar, Pooja Minj, Subash Godbole, Lalit Sahare , et al. · 2022

The results demonstrate that serum mixed with RNA protective solution and blotted on Whatman filter paper no 3 can be effectively used for diagnosis, serotyping and genotyping of DENVs. This will help in easy transportation, diagnosis and …

Identification of hepatitis B virus genotypes detected in Lahaul & Spiti district of Himachal Pradesh, India Open

Sanchita Pacholi, Subasa Chandra Bishwal, Pradip Barde · 2022

Background & objectives: Infection by hepatitis B virus (HBV) results in acute or chronic hepatitis. Based on sequence differences of eight per cent or more, HBV is divided into 10 genotypes (A to J) and 35 sub-genotypes. Molecular charact…

Profile of diseases prevalent in Datia District of Madhya Pradesh, India Open

Nalini Mishra, Pradip Barde, Sarvesh Awasthi, Archana Kumawat, Rajesh Gaur , et al. · 2022

Background and objectives Exploring the disease profile in a defined area helps policymakers to understand local health issues. It is essential to collect such information in countries, like India, which have a wide range of socioeconomic,…

Zika a Vector Borne Disease Detected in Newer States of India Amidst the COVID-19 Pandemic Open

Pragya D. Yadav, Harmanmeet Kaur, Nivedita Gupta, Rima R. Sahay, Gajanan Sapkal , et al. · 2022

Background During the second wave of the COVID-19 pandemic, outbreaks of Zika were reported from Kerala, Uttar Pradesh, and Maharashtra, India in 2021. The Dengue and Chikungunya negative samples were retrospectively screened to determine …

Expansion of the measles and rubella laboratory network, India Open

Deepa Sharma, Lucky Sangal, Neetu Vijay, Uma P. Nalavade, Kaveri Krishnasamy , et al. · 2022

The process led to strengthening and expansion of the network. This proficient laboratory network has helped India in scaling up serological and molecular testing of measles and rubella while ensuring high quality testing. The collaborativ…

Prevalence of Hepatitis D virus antibodies in Hepatitis B patients treated at tertiary care unit at Jabalpur Central India Open

Anjali Sonkar, Subasa C. Bishwal, Ravendra K. Sharma, Pradip Barde · 2021

Hepatitis Delta virus (HDV) infection amongst Hepatitis B virus (HBV) infected patients increases morbidity and mortality. The prevalence varies temporally and spatially. The present study aimed to evaluate the HDV prevalence in central In…

Nation-wide vector surveillance on Zika and Dengue did not indicate transmission of the American lineage-pandemic Zika virus in India Open

N. Pradeep Kumar, Ashwani Kumar, Panneer Devaraju, S. Abidha, S. Muthukumaravel , et al. · 2021

This investigation evinced no active transmission of the American lineage-pandemic Zika virus in India during the pandemic period.

Clinical Characterization and Genomic Analysis of Samples from COVID-19 Breakthrough Infections during the Second Wave among the Various States of India Open

Nivedita Gupta, Harmanmeet Kaur, Pragya D. Yadav, Labanya Mukhopadhyay, Rima R. Sahay , et al. · 2021

From March to June 2021, India experienced a deadly second wave of COVID-19, with an increased number of post-vaccination breakthrough infections reported across the country. To understand the possible reason for these breakthroughs, we co…

Seroprevalence of Dengue Infection Using IgG Capture ELISA in India, 2017–2018 Open

Muthusamy Santhosh Kumar, P Kamaraj, Siraj Ahmed Khan, Ramesh Reddy Allam, Pradip Barde , et al. · 2021

We conducted a nationally representative population-based survey in 60 districts from 15 Indian states covering all five geographic regions during 2017–2018 to estimate the age specific seroprevalence of dengue. Of the 12,300 sera collecte…

Clinical characterization and Genomic analysis of COVID-19 breakthrough infections during second wave in different states of India Open

Nivedita Gupta, Harmanmeet Kaur, Pragya D. Yadav, Labanya Mukhopadhyay, Rima R. Sahay , et al. · 2021

During March to June 2021 India has experienced a deadly second wave of COVID-19 with an increased number of post-vaccination breakthrough infections reported across the country. To understand the possible reason of these breakthroughs we …

Nation-wide vector surveillance did not indicate transmission of the “American lineage pandemic ZIKA virus” in India Open

N. Pradeep Kumar, P Jambulingam, Panneer Devaraju, S. Muthukumaravel, S. Abidha , et al. · 2021

Background In wake of the global health emergency declared by the World Health Organization (WHO) during 2016, on the outbreak of ZIKA pandemic, Indian Council of Medical Research (ICMR) carried out countrywide vector surveillance for ZIKA…

Molecular xenomonitoring of Dengue, Chikungunya and Zika infections Open

Gyan Chand, Subhash Godbole, L. Shivlata, Lalit Sahare, Mahendra Ukey , et al. · 2021

Background & objectives: Infections caused by arboviruses and transmitted by Aedes species mosquitoes are a serious health concern. India is endemic for diseases like Dengue, Chikungunya and recently Zika has been reported from few states.…

Molecular characterization of hepatitis B virus reveals circulation of multiple subgenotypes of genotype D with clinically important mutations in central India Open

L. Shivlata, Sanchita Pacholi, Vivek Chouksey, Pradip Barde · 2021

This maiden molecular study on HBV from central India indicates that the genotype D with subgenotypes D1, D2, D3 and D5 harbouring mutations of clinical and epidemiological importance are in circulation. This study will serve as a baseline…

Seroprevalence of chikungunya virus infection in India, 2017: a cross-sectional population-based serosurvey Open

Muthusamy Santhosh Kumar, P Kamaraj, Siraj Ahmed Khan, Ramesh Reddy Allam, Pradip Barde , et al. · 2021

Indian Council of Medical Research.

Hepatitis-B virus infection in India: Findings from a nationally representative serosurvey, 2017-18 Open

Manoj Murhekar, Muthusamy Santhosh Kumar, P Kamaraj, Siraj Ahmed Khan, Ramesh Reddy Allam , et al. · 2020

Children born after the introduction of HB vaccination had a lower prevalence of past HBV infection and a higher prevalence of anti-HBs. The findings of our study could be considered as an interim assessment of the impact of the hepatitis …

Prevalence of Torch Infections and Its Associated Poor Outcome in High-Risk Pregnant Women of Central India: Time to Think for Prevention Strategies Open

H. V. Manjunathachar, Kavita N. Singh, Vivek Chouksey, Ravindra Kumar, Ravendra K. Sharma , et al. · 2020

A high prevalence of IgM seropositivity of TORCH infection was noted in the present study with the increased rate of poor foetal outcome warrants the need of proper prenatal counselling, universal immunisation and nutritional supplements d…

Detection of Crimean-Congo hemorrhagic fever and theileriosis in livestock, Madhya Pradesh, Central India Open

Manjunathachar Vasanthachar, Chandrashekar Ganapat Raut, P.G. Tewari, Vivek Chouksey, Pradip Barde , et al. · 2020

Tick borne diseases impinge veterinary and public health, worldwide causing threat to nutritional security, mortality and huge economic losses. Crimean-Congo haemorrhagic fever (CCHF) and theileriosis are the two important tick-borne disea…

Seroprevalence and risk factors of hepatitis B virus infection in tribal population of Himalayan district Lahaul and Spiti, India Open

Ravendra K. Sharma, Mohan K. Shukla, Naveen Minhas, Pradip Barde · 2019

Hepatitis B virus (HBV) infection is an important health issue across the world. With 4% to 7% prevalence of HBV, India is designated as an intermediate endemic country. However, HBV prevalence is significantly high in some pockets of the …

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