Prakash Ghimire
YOU?
Author Swipe
View article: Carbapenemase Producing Multi Drug Resistant Klebsiella pneumoniae from a Referral Hospital in Nepal
Carbapenemase Producing Multi Drug Resistant Klebsiella pneumoniae from a Referral Hospital in Nepal Open
Background: This study aimed to assess the antimicrobial resistance rates of Acinetobacter species and Pseudomonas species isolated from clinical samples in an Antimicrobial Resistance (AMR) surveillance site in Gandaki Province, Nepal.Met…
View article: Effect of nutrient sources on growth and yield performance of mung bean (Vigna radiata L.) in western Terai, Nepal
Effect of nutrient sources on growth and yield performance of mung bean (Vigna radiata L.) in western Terai, Nepal Open
Mung bean ( Vigna radiata L.) is a multipurpose pulse crop, mostly cultivated as a catch crop in fallow land during the spring season between wheat and rice crops. An experiment entitled “Effect of nutrient sources on growth and yield perf…
View article: Stakeholder analysis for ‘One Health’ approach to tackle antimicrobial resistance
Stakeholder analysis for ‘One Health’ approach to tackle antimicrobial resistance Open
Antimicrobial resistance (AMR) and interventions to mitigate it are multisectoral, exhibiting super-wicked features that require intersectoral collaboration and synergy. Although AMR and mitigation strategies are pressing issues, their sol…
View article: Multidrug resistant Escherichia coli isolated at National Public Health Laboratory, Nepal
Multidrug resistant Escherichia coli isolated at National Public Health Laboratory, Nepal Open
Background: Antimicrobial resistance in Escherichia coli is mostly associated with ß-lactamases and carbapenemases enzyme production resulting in treatment challenges. This study was conducted with the aim to detect and characterize antimi…
View article: English Language Teaching in the Age of Artificial Intelligence: Tools, Techniques, and Methodologies
English Language Teaching in the Age of Artificial Intelligence: Tools, Techniques, and Methodologies Open
This article discusses the perspective of generative artificial intelligence (GenAI) to transform English language teaching (ELT) practices. The article briefly remarks the current trends in ELT, including traditional grammar-translation t…
View article: Detection of plasmid-mediated mcr-1 gene in multidrug-resistant Escherichia coli from clinical specimens at a tertiary hospital in Nepal
Detection of plasmid-mediated mcr-1 gene in multidrug-resistant Escherichia coli from clinical specimens at a tertiary hospital in Nepal Open
Background: The emergence of antibiotic resistance, particularly plasmid-mediated colistin resistance, poses a critical threat to global public health, given colistin’s role as a last-resort antibiotic for treating multidrug-resistant (MDR…
View article: The Genotypes/Subtypes and Antiviral Drug Resistance of the Hepatitis C Virus from Patients in a Tertiary Care Hospital in Nepal
The Genotypes/Subtypes and Antiviral Drug Resistance of the Hepatitis C Virus from Patients in a Tertiary Care Hospital in Nepal Open
While direct-acting antivirals (DAAs) are available for the treatment of chronic Hepatitis C virus (HCV) patients in Nepal, knowledge of the circulating genotypes/subtypes and drug target gene mutations of HCV is currently unavailable. Her…
View article: Management of Root-Knot Nematodes with Chemical and Nonchemical Pesticides of Tomato under Protected Cultivation
Management of Root-Knot Nematodes with Chemical and Nonchemical Pesticides of Tomato under Protected Cultivation Open
Protected (plastic house) cultivation offers numerous advantages for vegetable production in Nepal. Continuous cropping cycles within soil-based closed structures have led to a rise in soil-borne pathogens, notably in the mid-hills of Nepa…
View article: A Cross-Sectional Survey of Aedes Aegypti and Aedes Albopictus Immature In the Discarded Tires
A Cross-Sectional Survey of Aedes Aegypti and Aedes Albopictus Immature In the Discarded Tires Open
Vector surveillances are done periodically, to know the prevalent mosquito in a locality, to predict the outbreak of mosquito-borne diseases, to derive effective vector control strategies, etc. Surveillance of different containers would he…
View article: Trends of Hepatitis Virus Infections in a Tertiary Care Hospital in Nepal, 2012-2023
Trends of Hepatitis Virus Infections in a Tertiary Care Hospital in Nepal, 2012-2023 Open
Objectives: To monitor the trends of incidence of different hepatitis virus infections during 2012–2023 in a tertiary care hospital in Nepal. Methods: A descriptive study was conducted using demographic and serological data from 2012 to 20…
View article: Screening of Phytochemicals and Antibacterial Property of Medicinal and Aromatic Plants of Nepal
Screening of Phytochemicals and Antibacterial Property of Medicinal and Aromatic Plants of Nepal Open
Medicinal and aromatic plants (MAPs) are gaining much attention as alternative therapy due to constant failure of chemotherapeutic agents. So, this study was conducted to screen the presence of different phytochemicals in MAPs and assess t…
View article: Comparison of Beta-lactamase Resistance Gene Detection in MDR Escherichia coli Isolates in Nepal
Comparison of Beta-lactamase Resistance Gene Detection in MDR Escherichia coli Isolates in Nepal Open
Objectives: To compare ESBL and carbapenemase gene detection using phenotypic (double disc diffusion and VITEK-2AES), and genotypic (PCR) methods in the E. coli isolates in Nepal. Methods: 132 multidrug resistant E. coli isolates with phen…
View article: Malaria elimination challenges in countries approaching the last mile: a discussion among regional stakeholders
Malaria elimination challenges in countries approaching the last mile: a discussion among regional stakeholders Open
In countries approaching malaria elimination, resourcing community-based health workers could play a critical role in enhancing malaria surveillance, early case detection and treatment, including interventions targeting migrant populations…
View article: Systematic review and individual patient data meta-analysis on glucose- 6 – phosphate dehydrogenase activities measured by a semi-quantitative handheld Biosensor
Systematic review and individual patient data meta-analysis on glucose- 6 – phosphate dehydrogenase activities measured by a semi-quantitative handheld Biosensor Open
Measurement of glucose-6-phosphate dehydrogenase (G6PD) activity guides hypnozoitocidal treatment of P. vivax malaria. The G6PD Standard (SDBiosensor, Republic of Korea) here referred to as “Biosensor” is a quantitative point-of-care diagn…
View article: Epidemiological Characteristics of Hepatitis C Patients Attending a Tertiary Care Hospital
Epidemiological Characteristics of Hepatitis C Patients Attending a Tertiary Care Hospital Open
Background: Hepatitis C infection is a major public health concern in Nepal. Epidemiological information on hepatitis C virus along with the status of co-infection with hepatitis B virus and human immunodeficiency virus is essential to con…
View article: Retraction notice to “Productivity and profitability of black rice as affected by transplanting methods and crop geometry” [Heliyon volume 10/14 2024 e34741]
Retraction notice to “Productivity and profitability of black rice as affected by transplanting methods and crop geometry” [Heliyon volume 10/14 2024 e34741] Open
View article: Limitations of Normal CSF Cell Counts in Excluding Bacterial Meningitis: A Multicentric Hospital Based Study in Kathmandu, Nepal
Limitations of Normal CSF Cell Counts in Excluding Bacterial Meningitis: A Multicentric Hospital Based Study in Kathmandu, Nepal Open
An increase in cerebrospinal fluid (CSF) cell count is an indicator of the diagnosis of bacterial meningitis. However, studies have reported that few bacterial meningitis cases showed no abnormalities in initial CSF analysis. Therefore, th…
View article: A Study on Synthesis and Characterization of Bio-Plastic Obtained from Potato
A Study on Synthesis and Characterization of Bio-Plastic Obtained from Potato Open
The synthesis of bioplastic is a growing interest among researchers in today’s world. Starch extracted from potatoes was utilized to synthesize bioplastic. From raw potatoes starch was extracted after it was peeled, diced, crushed, blended…
View article: Drug-related problems among type 2 diabetic patients in Sunwal Municipality of Western Nepal
Drug-related problems among type 2 diabetic patients in Sunwal Municipality of Western Nepal Open
Background Several diseases co-exist with diabetes such as hypertension, and dyslipidemia, leading to cases of non-adherence, several drug interactions, and an increased risk of adverse drug reactions among patients, which are often termed…
View article: Study on Omission Plot Technique in Popcorn
Study on Omission Plot Technique in Popcorn Open
There are various limiting factors in production of popcorn in Nepal among one of them is lack of limited information on nutrient management particularly the macronutrient nitrogen, phosphorous and potassium. Therefore, a field experiment …
View article: Gene Xpert based detection of drug resistant tuberculosis among retreatment patients visiting National Tuberculosis Centre, Nepal
Gene Xpert based detection of drug resistant tuberculosis among retreatment patients visiting National Tuberculosis Centre, Nepal Open
Introduction: Tuberculosis is still one of the major public health problems in Nepal and multi drug resistant and extensively drug resistant tuberculosis (MDR /XDRTB) additionally has become serious issue. Prompt diagnosis and effective tr…
View article: Effect of Nutrient Sources on Productivity of Spring Maize (Zea Mays L.) at Khairahani, Chitwan, Nepal
Effect of Nutrient Sources on Productivity of Spring Maize (Zea Mays L.) at Khairahani, Chitwan, Nepal Open
Maize is second most important crop of Nepal grown mostly for food, feed and fodder. While many biotic and abiotic factors may lead to yield gaps in maize, soil fertility degradation and poor nutrient management are major factors in low pr…
View article: RETRACTED: Productivity and profitability of black rice as affected by transplanting methods and crop geometry
RETRACTED: Productivity and profitability of black rice as affected by transplanting methods and crop geometry Open
Black rice is a highly nutritious cereal that has been introduced to Nepal recently. Due to its late introduction, only a few agronomic research have been conducted so far. Hence, farmers are not aware about the appropriate transplanting m…
View article: Influence of seed priming in the germination and yield performances of common buckwheat
Influence of seed priming in the germination and yield performances of common buckwheat Open
The study, conducted from November 2019 to March 2020 at the Institute of Agriculture and Animal Science in Rupandehi, Nepal, aimed to evaluate the effects of seed priming techniques on common buckwheat. The experiment comprised eleven tre…
View article: Extended Spectrum Beta Lactamase Escherichia Coli in Bagmati River, Kathmandu Valley
Extended Spectrum Beta Lactamase Escherichia Coli in Bagmati River, Kathmandu Valley Open
Background: Antimicrobial resistance organisms in the peripheral communities of an environment can be predicted by the presence of extended-spectrum beta-lactamase Escherichia coli in that environment. The close connectivity between humans…
View article: Efficacy of Native Bacillus thuringiensis against Mosquito Vector
Efficacy of Native Bacillus thuringiensis against Mosquito Vector Open
Background: Larval source management is an effective measure to control mosquito-borne diseases. Bacillus thuringiensis produces specific insecticidal crystal proteins toxic to mosquito larvae. In many parts of the South East Asian region,…
View article: Metallo-β-lactamase-producing Pseudomonas aeruginosa Isolates from Two Tertiary Care Centres in a District of Nepal: A Descriptive Cross-sectional Study
Metallo-β-lactamase-producing Pseudomonas aeruginosa Isolates from Two Tertiary Care Centres in a District of Nepal: A Descriptive Cross-sectional Study Open
Introduction: Pseudomonas aeruginosa isolates producing metallo-β-lactamase have caused nosocomial outbreaks, severe infections, and ineffective carbapenem therapy worldwide since 1991. Due to their prevalence, hospital infection control t…
View article: Source Tracing of <i>Leishmania donovani</i> in Emerging Foci of Visceral Leishmaniasis, Western Nepal
Source Tracing of <i>Leishmania donovani</i> in Emerging Foci of Visceral Leishmaniasis, Western Nepal Open
We sequenced Leishmania donovani genomes in blood samples collected in emerging foci of visceral leishmaniasis in western Nepal. We detected lineages very different from the preelimination main parasite population, including a new lineage …
View article: Field assessment of the operating procedures of a semi-quantitative G6PD Biosensor to improve repeatability of routine testing
Field assessment of the operating procedures of a semi-quantitative G6PD Biosensor to improve repeatability of routine testing Open
In remote communities, diagnosis of G6PD deficiency is challenging. We assessed the impact of modified test procedures and delayed testing for the point-of-care diagnostic STANDARD G6PD (SDBiosensor, RoK), and evaluated recommended cut-off…
View article: Phylogeny of a Mosquitocidal Bacillus thuringiensis var israelensis
Phylogeny of a Mosquitocidal Bacillus thuringiensis var israelensis Open
Objectives: The study aims to compare the 16srRNA sequence of Bacillus thuringiensis var israelensis available in the National Center for Biotechnology Information, database, the sequence length, the relatedness, identity, and ancestral pr…