Explanipedia

Baseline White Matter Is Associated With Physical Fitness Change in Preclinical Alzheimer’s Disease Open

Vijay Venkatraman, Christopher Steward, Kay L. Cox, Kathryn A. Ellis, Pramit M. Phal , et al. · 2020

White matter (WM) microstructure is a sensitive marker to distinguish individuals at risk of Alzheimer's disease. The association of objective physical fitness (PF) measures and WM microstructure has not been explored and mixed results rep…

A Randomized Controlled Trial of Adherence to a 24-Month Home-Based Physical Activity Program and the Health Benefits for Older Adults at Risk of Alzheimer’s Disease: The AIBL Active-Study Open

Kay L. Cox, Elizabeth Cyarto, Kathryn A. Ellis, David Ames, Patricia Desmond , et al. · 2018

Background: Previous studies have demonstrated that physical activity (PA) interventions can improve physical and cognitive outcomes in older adults, but most have been relatively short in duration (<1 year) with a few having specifically …

Comparison between site and central radiological assessments for patients with recurrent glioblastoma on a clinical trial Open

Kathryn Field, Greg Fitt, Mark Rosenthal, John Simes, Anna K. Nowak , et al. · 2017

Aim Assessment of magnetic resonance imaging (MRI) in glioblastoma can be challenging. For patients with recurrent glioblastoma managed on the CABARET trial, we compared disease status assessed at hospitals and subsequent blinded central e…

The role of early magnetic resonance imaging in predicting survival on bevacizumab for recurrent glioblastoma: Results from a prospective clinical trial (CABARET) Open

Kathryn Field, Pramit M. Phal, Greg Fitt, Christine Goh, Anna K. Nowak , et al. · 2017

BACKGROUND Bevacizumab has been associated with prolonged progression‐free survival for patients with recurrent glioblastoma; however, not all derive a benefit. An early indicator of efficacy or futility may allow early discontinuation for…

Continuing or ceasing bevacizumab beyond progression in recurrent glioblastoma: an exploratory randomized phase II trial Open

Elizabeth Hovey, Kathryn Field, Mark Rosenthal, Elizabeth H. Barnes, Lawrence Cher , et al. · 2017

Background In patients with recurrent glioblastoma, the benefit of bevacizumab beyond progression remains uncertain. We prospectively evaluated continuing or ceasing bevacizumab in patients who progressed while on bevacizumab. Methods CABA…

Assessment of Optic Pathway Structure and Function in Patients With Compression of the Optic Chiasm: A Correlation With Optical Coherence Tomography Open

Pramit M. Phal, Christopher Steward, Andrew D. Nichols, Chris Kokkinos, Patricia Desmond , et al. · 2016

Damage to the retinal nerve fiber layer is associated with downstream structural and functional degradation of the optic pathway. This may be related to trans-synaptic degeneration and the fact that these factors are important potential im…

Imaging characteristics of nodal metastases in paraganglioma, ameloblastoma and olfactory neuroblastoma: case reports and literature review Open

Smita Deb, Tim A. Iseli, Timothy Wong, Pramit M. Phal · 2016

Paraganglioma, ameloblastoma and olfactory neuroblastoma are uncommon primary head and neck tumours. When nodal metastases from these tumours occur, they may present later than and with different imaging characteristics compared with squam…

Concomitant extraspinal hyperostosis and osteoporosis in a patient with congenital ichthyosis Open

Niloufar Torkamani, Pramit M. Phal, Ravi Savarirayan, Peter Simm, George Varigos , et al. · 2016

Ichthyosiform dermatosis is a term referred to a group of disorders that have as their basis a disorder of keratinization (1). These conditions which are present at birth result in a generalized dry, scaly skin without any inflammation. Th…

Alterations in dorsal and ventral posterior cingulate connectivity in APOE<i>ε</i>4 carriers at risk of Alzheimer's disease Open

Rebecca Kerestes, Pramit M. Phal, Chris Steward, Bradford A. Moffat, Simon Salinas , et al. · 2015

Background Recent evidence suggests that exercise plays a role in cognition and that the posterior cingulate cortex (PCC) can be divided into dorsal and ventral subregions based on distinct connectivity patterns. Aims To examine the effect…

A Pictorial Review of Brachial Plexus MRI Open

Shu Su, Craig Hacking, Pramit M. Phal · 2015

Poster: 2015 ASM / R-0010 / A Pictorial Review of Brachial Plexus MRI by: S. Su , C. Hacking, P. M. Phal; Melbourne/AU

Semi‐automated hippocampal segmentation in people with cognitive impairment using an age appropriate template for registration Open

B. Merkel, Christopher Steward, Lucy Vivash, Charles B. Malpas, Pramit M. Phal , et al. · 2015

Background To evaluate a new semi‐automated segmentation method for calculating hippocampal volumes and to compare results with standard software tools in a cohort of people with subjective memory complaints (SMC) and mild cognitive impair…

Randomized phase 2 study of carboplatin and bevacizumab in recurrent glioblastoma Open

Kathryn Field, John Simes, Anna K. Nowak, Lawrence Cher, Helen Wheeler , et al. · 2015

ACTRN12610000915055.

Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer Open

Matthew Hong, Geoff Macintyre, David C. Wedge, Peter Van Loo, Keval Patel , et al. · 2015

Probabilistic MRI Tractography of the Optic Radiation Using Constrained Spherical Deconvolution: A Feasibility Study Open

Jeremy C. Lim, Pramit M. Phal, Patricia Desmond, Andrew D. Nichols, Chris Kokkinos , et al. · 2015

Accurate tractography of the optic radiation can be accomplished using diffusion MRI data collected within a clinically practical timeframe. CSD based tractography was faster, more accurate and had better correlation with known anatomical …

Extensive leptomeningeal metastases Open

Dayu Gai, Pramit M. Phal · 2015

Spinal astrocytoma Open

Pramit M. Phal · 2015

Spinal lymphoma Open

Pramit M. Phal · 2015

Vertebral body metastasis Open

Magdalena Chmiel-Nowak, Pramit M. Phal · 2015

Aggressive spinal haemangioma Open

Pramit M. Phal · 2015

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