Prasanna Vadhana Ashok Kumaar
YOU?
Author Swipe
View article: Amyloid-β-driven Alzheimer’s disease reshapes the colonic immune system in mice
Amyloid-β-driven Alzheimer’s disease reshapes the colonic immune system in mice Open
View article: Multiplexed Targeted Spatial Mass Spectrometry Imaging Assays to monitor lipids and NAD+ metabolites in CD38 knockout mice exhibiting improved metabolism
Multiplexed Targeted Spatial Mass Spectrometry Imaging Assays to monitor lipids and NAD+ metabolites in CD38 knockout mice exhibiting improved metabolism Open
View article: Multiplexed Targeted Spatial Mass Spectrometry Imaging Assays to monitor lipids and NAD<sup>+</sup>metabolites in CD38 knockout mice exhibiting improved metabolism
Multiplexed Targeted Spatial Mass Spectrometry Imaging Assays to monitor lipids and NAD<sup>+</sup>metabolites in CD38 knockout mice exhibiting improved metabolism Open
Mass spectrometry imaging (MSI) is a rapidly advancing technology that provides mapping of the spatial molecular landscape of tissues for a variety of analytes. Matrix- assisted laser desorption/ionization (MALDI)-MSI is commonly employed,…
View article: ACUTE NAD+ SUPPLEMENTATION MODULATES SYSTEMIC INFLAMMATION IN A LPS-INDUCED DELIRIUM MOUSE MODEL
ACUTE NAD+ SUPPLEMENTATION MODULATES SYSTEMIC INFLAMMATION IN A LPS-INDUCED DELIRIUM MOUSE MODEL Open
Delirium is a serious neuropsychiatric condition that lacks an effective treatment intervention. A confusional state often brought on by acute illness, delirium is associated with acute inflammation and metabolic dysfunction. NAD+ is a met…
View article: CD38 regulates ovarian function and fecundity via NAD+ metabolism
CD38 regulates ovarian function and fecundity via NAD+ metabolism Open
View article: CD38 regulates ovarian function and fecundity via NAD<sup>+</sup>metabolism
CD38 regulates ovarian function and fecundity via NAD<sup>+</sup>metabolism Open
Summary Mammalian female reproductive lifespan is typically significantly shorter than life expectancy and is associated with a decrease in ovarian NAD+ levels. However, the mechanisms underlying this loss of ovarian NAD+ are unclear. Here…
View article: Nicotinamide Mononucleotide Administration Prevents Doxorubicin-Induced Cardiotoxicity and Loss in Physical Activity in Mice
Nicotinamide Mononucleotide Administration Prevents Doxorubicin-Induced Cardiotoxicity and Loss in Physical Activity in Mice Open
Doxorubicin (Doxo) is a widely used antineoplastic drug with limited clinical application due to its deleterious dose-related side effects. We investigated whether nicotinamide mononucleotide (NMN) could protect against Doxo-induced cardio…