Explanipedia

Microbial Diversity and Infection Burden in Central Nervous System (CNS) Shunt and Drain Devices: A Prospective Observational Study Open

Sheetal Agarwal, Prashant Gupta, Vimala Venkatesh, Chhitij Srivastava · 2025

Our study highlights that DAIs are more prevalent with EVDs and are predominantly caused by Gram-negative organisms, with K. pneumoniae being the most frequently isolated. The susceptibility patterns underscore the need for …

Multidrug-Resistant Candida in Bloodstream Infections: A Growing Concern in Indian Healthcare Open

Shailendra Yadav, D Himanshu, Prashant Gupta, Anuradha Nischal, Virendra Atam , et al. · 2025

ENSURING DIAGNOSTIC EXCELLENCE: REVIEW ON QA PRINCIPLES IN CONVENTIONAL AND DIGITAL RADIOLOGY Open

Ms. Anjali Singh Raghav, Mr. Vishal Gangwar, Mr. Rahul Gangwar, Prashant Gupta · 2025

Ensuring diagnostic excellence in radiology heavily relies on the implementation of robust Quality Assurance (QA) programs. Both conventional and digital radiology systems demand high standards of operational efficiency to guarantee accura…

Advancing Fungal Diagnostic and Research Stewardship in India: A Prospective Strategic 10-Step Plan for Addressing a National Public Health Challenge Open

Madhuchhanda Das, Venencia Albert, Saurabh Sharma, Gagandeep Singh, Vinaykumar Hallur , et al. · 2025

Invasive fungal infections (IFIs) are silent killers, frequently undiagnosed and untreated. India faces significant challenges with limited diagnostic facilities, scarce data on fungal infection, and rising antifungal resistance. The COVID…

Characterization of Burkholderia Species from Various Clinical Specimens and their Antimicrobial Susceptibility Patterns Open

Nishtha Singh, Sheetal Verma, Amber Azim, Vimala Venkatesh, Raj Kumar Kalyan , et al. · 2025

A case report of disseminated histoplasmosis not responding to primary treatment by itraconazole. Open

Prashant Gupta, Kalpana Kuntal, Nishant Gupta, Anand K. Srivastava · 2025

This case highlights the importance of timely recognition and adjustment of treatment in non-severe histoplasmosis, particularly for patients who do not respond adequately to itraconazole therapy.

Genital Tract Infections and Their Correlation with Sociodemographic Features among Infertile Women at a Tertiary Care Center Open

Agarwal Ak, Prashant Gupta, Renu Kumari, Vimala Venkatesh, Diksha Shukla , et al. · 2024

Correlation of lipid profile APO A1 and APO B100 in chronic periodontitis patients leading to coronary artery disease Open

Shilpi Gupta, Nand Lal, Wahid Ali, Akshyaya Pradhan, Ajay Verma , et al. · 2024

Background: Increased attention has been focused on the association of periodontal disease with cardio-metabolic syndrome. Although the associations are multi-factorial, very few studies have explored the role of lipoprotein Apo A1 and Apo…

An Autonomous Implantable Device for the Prevention of Death from Opioid Overdose Open

Joanna L. Ciatti, Abraham Vázquez‐Guardado, Victoria E. Brings, Jihun Park, Brian C. Ruyle , et al. · 2024

Opioid overdose accounts for nearly 75,000 deaths per year in the United States, representing a leading cause of mortality amongst the prime working age population (25-54 years). At overdose levels, opioid-induced respiratory depression be…

To evaluate the relationship of obstructive sleep apnea with chronic periodontitis and its association with coronary artery disease by assessing serum tumor necrosis factor-α Open

Shilpi Gupta, Nand Lal, Wahid Ali, Akshyaya Pradhan, Ajay Verma , et al. · 2024

The periodontal tissue initiates an immune-inflammatory response against bacteria and their products at the site of periodontal infection, and systemic attack by these pathogens triggers an acute phase response that contributes to the syst…

Long COVID and Perimenopause Open

Savita Somalwar, Prabhat Agrawal, Prashant Gupta, Ruchika Garg · 2024

Coronavirus disease-2019 (COVID-19) has created a huge impact globally.It created great havoc and claimed many lives.It left a trail on those who survived.Long COVID also known as post-acute sequelae of SARS-CoV-2 infection (PASC) affects …

Pan-Indian Clinical Registry of Invasive Fungal Infections Among Patients in the Intensive Care Unit: Protocol for a Multicentric Prospective Study Open

Anup Kumar Ojha, Venencia Albert, Saurabh Sharma, Vinaykumar Hallur, Gagandeep Singh , et al. · 2024

Background Fungal infections are now a great public health threat, especially in those with underlying risk factors such as neutropenia, diabetes, high-dose steroid treatment, cancer chemotherapy, prolonged intensive care unit stay, and so…

The socio-demographic profile and clinical correlation of Chlamydia trachomatis among infertile women at a tertiary care center in North India Open

Diksha Shukla, Raj Kumar Kalyan, Prashant Gupta, Vimala Venkatesh, Agarwal Ak · 2024

Background: The frequency of Chlamydia trachomatis infection in infertile Indian women and potential risk factors associated with the infection is not well understood. To improve the primordial prevention C. trachomatis infection in develo…

The Development of a Clinical Registry Digital Database on Invasive Fungal Infections in India: Advancing Epidemiological Understanding and Patient Care Open

Harleen Kaur, Kh. Jitenkumar Singh, Saurabh Sharma, Madhuchhanda Das, Venencia Albert , et al. · 2024

A well-structured digital database is essential for any national priority project as it can provide real-time data analysis and facilitate quick decision making. In recent times, particularly after the COVID-19 pandemic, invasive fungal in…

Evaluation of the efficacy of novel topical antifungal agents against dermatophytes in North India: A prospective study. Open

Tanya Sachan, Prashant Gupta, Swastika Suvirya, Parul Verma, Raj Kumar Kalyan , et al. · 2024

The results from the present study on the in vitro performance of newer topical antifungals suggested that they hold significant promise as prospective candidates for advancing the development of new antifungal treatments for dermat…

Periodontal health status in patients with lung cancer: Case-control study. Open

Pooja Singh, Umesh Pratap Verma, Ajay Kumar Verma, Prashant Gupta, Anjani Kumar Pathak , et al. · 2024

The study findings demonstrated significantly higher clinical and biochemical markers in patients with both lung cancer and chronic periodontitis, in comparison to individuals with chronic periodontitis alone and healthy participants. Thes…

A Comparison Between Potassium Hydroxide (KOH) Microscopy and Culture for the Detection of Post-COVID-19 Rhino-Orbital-Cerebral Mucormycosis Open

Saqib Hasan, Prashant Gupta, Diksha Shukla, Gopa Banerjee · 2023

Talazoparib plus enzalutamide for metastatic castration-resistant prostate cancer: TALAPRO-2 trial Open

Prashant Gupta · 2023

Nasopharyngeal carriage of Streptococcus pneumoniae serotypes among sick and healthy children in northern India: A case-control study Open

Neha Verma, Prashant Gupta, Anuj Kumar Pandey, Shally Awasthi · 2023

Association of Interleukin-1 Receptor Antagonist (IL-1RA) Gene Polymorphism with Community-Acquired Pneumonia in North Indian Children: A Case–Control Study Open

Neha Verma, Shally Awasthi, Anuj Kumar Pandey, Prashant Gupta · 2023

Background Community-acquired pneumonia (CAP) is the leading cause of death in children < 5 years of age. The primary objective of the study was to assess the association of IL-1RA gene polymorphism in children aged 2 to 59 months with CAP…

Association of Virulence Markers With Resistance to Oral Antibiotics in Escherichia coli Isolates Causing Uncomplicated Community-Acquired Cystitis Open

Shruti Radera, Jyotsna Agarwal, Sugandha Srivastava, Prashant Gupta, Amita Pandey · 2023

The results of the present study clearly show the association of VFs with some of the commonly used oral antibiotics emphasizing the need for further molecular studies and surveillance programs to monitor drug-resistant UPEC so as to form …

Nasopharyngeal Carriage of Streptococcus pneumoniae Serotypes Among Healthy Children in Northern India Open

Prashant Gupta, Shally Awasthi, Umesh Gupta, Nishu Verma, Tuhina Rastogi , et al. · 2022

Mucocutaneous manifestations of COVID-19-associated mucormycosis: A retrospective cross-sectional study Open

Sonal Sachan, Swastika Suvirya, Krishna Kumar Yadav, Prashant Gupta, Abir Saraswat , et al. · 2022

Background Cutaneous mucormycosis has shown a significant upsurge during the COVID-19 pandemic. Due to the rapid progression and high mortality of cutaneous mucormycosis in this context, it is important to identify it early. However, very …

A case control investigation of COVID-19 associated mucormycosis in India Open

Tanu Anand, Aparna Mukherjee, Aanchal Satija, Poonam Sharma Velamuri, Kh. Jitenkumar Singh , et al. · 2022

T‐cell dysfunction as a potential contributing factor in <span>post‐COVID</span>‐19 mucormycosis Open

Himanshu Dandu, Manish Kumar, Hardeep Singh Malhotra, Naveen Kumar, Neeraj Kumar , et al. · 2022

Background The second wave of COVID‐19 in India was followed by large number of mucormycosis cases. Indiscriminate use of immunosuppressive drugs, underlying diseases such as diabetes, cancers, or autoimmune diseases was thought to be the …

Molecular Characterization of Extended Spectrum β-Lactamase Producing Escherichia coli and Klebsiella pneumoniae Isolates and Their Antibiotic Resistance Profile in Health Care-Associated Urinary Tract Infections in North India Open

Sheetal Verma, Raj Kumar Kalyan, Prashant Gupta, Mohd Danish Khan, Vimala Venkatesh · 2022

Background Healthcare-associated urinary tract infections (HAUTIs) caused by gram-negative pathogens have emerged as a global concern. So far, little is known about the epidemiology of extended-spectrum β lactamase (ESBL)-producing Escheri…

Determinants of stroke in patients with rhino cerebral mucormycosis seen during the second wave of COVID-19 pandemic: A prospective cohort study Open

Shweta Pandey, Hardeep Singh Malhotra, Ravindra Kumar Garg, Kamini Sharma, Imran Rizvi , et al. · 2022

An overview of mycetoma and its diagnostic dilemma: Time to move on to advanced techniques Open

Uneza Husain, Parul Verma, Swastika Suvirya, Ketan Priyadarshi, Prashant Gupta · 2022

The neglected tropical disease mycetoma can become extremely devastating, and can be caused both by fungi and bacteria; these are popularly known as eumycetoma and actinomycetoma respectively. The classical triad of the disease is subcutan…

P047 Comparative evaluation of disc diffusion and E-test with broth micro-dilution in susceptibility testing of amphotericin B, posaconazole, isuvuconazole, itraconazole against <i>Rhizopus</i> isolates of post COVID mucormycosis Open

Prashant Gupta, Mohd Saqib Hasan · 2022

Poster session 1, September 21, 2022, 12:30 PM - 1:30 PM Objectives To investigate and compare susceptibility pattern of Rhizopus isolates in post-COVID mucormycosis by disc diffusion (DD), E-test, and broth micro-dilution for amphotericin…

Health-care-associated bloodstream and urinary tract infections in a network of hospitals in India: a multicentre, hospital-based, prospective surveillance study Open

Purva Mathur, Paul Malpiedi, Kāmini Walia, Padmini Srikantiah, Sunil Gupta , et al. · 2022

For the Hindi translation of the abstract see Supplementary Materials section.

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